Ruptured intracranial aneurysms: The preoperative management and the timing of surgery

1982 ◽  
Vol 63 (1-4) ◽  
pp. 147-151
Author(s):  
C. Cecotto ◽  
P. P. Janes ◽  
F. de Nardi ◽  
C. Mazzoli ◽  
G. Nicolella
Keyword(s):  
Intracranial Aneurysms ◽  
Timing Of Surgery ◽  
Preoperative Management ◽  
Ruptured Intracranial Aneurysms

Preoperative management of patients with ruptured intracranial aneurysms

1972 ◽  
Vol 36 (5) ◽  
pp. 525-530 ◽  
Author(s):  
Joseph Ransohoff ◽  
Albert Goodgold ◽  
M. Vallo Benjamin
Keyword(s):  
Cerebral Vasospasm ◽  
Intracranial Aneurysms ◽  
Preoperative Management ◽  
Early Recovery ◽  
Content Type ◽  
Antifibrinolytic Agent ◽  
Definitive Surgery ◽  
Additional Reduction ◽  
Ruptured Intracranial Aneurysms ◽  
Fine Print

✓ The authors report their experience with the use of an antifibrinolytic agent and hypotensive drugs in the prevention of rebleeding from recently ruptured intracranial aneurysms and conclude that both measures are of suggestive value. With further refinement in these techniques an additional reduction of early rebleeding may be expected. Secondary cerebral vasospasm remains the major obstacle to early recovery and definitive surgery for ruptured intracranial aneurysms.

Significance of vasospasm in the treatment of ruptured intracranial aneurysms

1977 ◽  
Vol 47 (3) ◽  
pp. 412-429 ◽  
Author(s):  
Isamu Saito ◽  
Yasuichi Ueda ◽  
Keiji Sano
Keyword(s):  
Intracranial Aneurysms ◽  
Surgical Intervention ◽  
Blood Clot ◽  
Timing Of Surgery ◽  
Neurological Deficits ◽  
Aneurysm Surgery ◽  
Content Type ◽  
Ruptured Intracranial Aneurysm ◽  
Ruptured Intracranial Aneurysms ◽  
Fine Print

✓ The authors have analyzed a total of 96 consecutive cases in which vasospasm followed subarachnoid hemorrhage (SAH). The SAH was caused by ruptured intracranial aneurysm or developed after aneurysm surgery. Usually at least 4 days elapsed between SAH and the onset of vasospasm. Vasospasm subsided an average of 2 weeks after onset. Of 68 patients with preoperative vasospasm, eight died due to cerebral edema resulting from ischemia, and 49% of the survivors had neurological deficits. Preoperative vasospasm was not aggravated by surgical intervention when operations were carried out more than 7 days after the onset of vasospasm. Postoperative vasospasm was found in 25 of 52 patients who underwent operation within 1 week after SAH (excluding cases in Grade V). Five of these patients died, all of whom underwent surgery between the fourth and seventh day after SAH (the day of SAH was counted as the first day). There were no deaths among 20 patients operated on within the first 3 days after SAH. Postoperative vasospasm was always mild in these cases, when it occurred, probably because blood clot or blood-stained cerebrospinal fluid was removed by operative procedures. In all cases, 4 to 11 days elapsed between the last SAH and the onset of postoperative vasospasm regardless of the timing of surgery.

Use of epsilon aminocaproic acid (EACA) in the preoperative management of ruptured intracranial aneurysms

1976 ◽  
Vol 44 (4) ◽  
pp. 479-484 ◽  
Author(s):  
Ram P. Sengupta ◽  
Sing C. So ◽  
Francisco J. Villarejo-Ortega
Keyword(s):  
Intracranial Aneurysms ◽  
Aminocaproic Acid ◽  
Preoperative Period ◽  
Preoperative Management ◽  
Recurrent Hemorrhage ◽  
Content Type ◽  
Antifibrinolytic Therapy ◽  
Similar Series ◽  
Epsilon Aminocaproic Acid ◽  
Ruptured Intracranial Aneurysms

✓ The authors report their experience with the use of epsilon aminocaproic acid (EACA) in the preoperative management of a series of patients with ruptured intracranial aneurysms. A similar series of patients was taken as control. They found that EACA is of definite value in preventing recurrent hemorrhage in the preoperative period. The significance of antifibrinolytic therapy in ruptured intracranial aneurysms is discussed.

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