The effects of norepinephrine on hemodynamics and renal function in severe septic shock states

1993 ◽  
Vol 19 (3) ◽  
pp. 151-154 ◽  
Author(s):  
E. M. Redl-Wenzl ◽  
C. Armbruster ◽  
G. Edelmann ◽  
E. Fischl ◽  
M. Kolacny ◽  
...  
Keyword(s):  
Septic Shock ◽  
Renal Function ◽  
Severe Septic Shock

The effects of vasopressin on hemodynamics and renal function in severe septic shock: a case series

2001 ◽  
Vol 27 (8) ◽  
pp. 1416-1421 ◽  
Author(s):  
Cheryl L. Holmes ◽  
Keith R. Walley ◽  
Dean R. Chittock ◽  
Tara Lehman ◽  
James A. Russell
Keyword(s):  
Septic Shock ◽  
Renal Function ◽  
Case Series ◽  
Severe Septic Shock

scholarly journals Hemoadsorption in a Case of Severe Septic Shock and Necrotizing Fasciitis Caused by Nontraumatic Renal Rupture due to Pyelonephritis with Obstructive Uropathy

2018 ◽  
Vol 2018 ◽  
pp. 1-4 ◽  
Author(s):  
Lampros Kousoulas ◽  
Uwe Wittel ◽  
Stefan Fichtner-Feigl ◽  
Stefan Utzolino
Keyword(s):  
Septic Shock ◽  
Renal Function ◽  
Necrotizing Fasciitis ◽  
Lower Limb ◽  
Rescue Therapy ◽  
Obstructive Uropathy ◽  
Combined Treatment ◽  
Retroperitoneal Abscess ◽  
Renal Rupture ◽  
Severe Septic Shock

Background. Nontraumatic renal rupture due to pyelonephritis with obstructive uropathy is an uncommon but life-threatening situation. Case Presentation. A 25-year-old female presented to the emergency department with acute worsening of abdominal pain that began four weeks earlier. She was found to have peritonitis, leukocytosis, severe lactic acidosis, and a pronounced anemia and imaging was consistent with nontraumatic renal rupture with retroperitoneal abscess, perforation of the colon, and severe necrotizing fasciitis of the right lower limb. She underwent a right nephrectomy, a right hemicolectomy, surgical debridement of the retroperitoneum, and an upper thigh amputation. Due to severe septic shock and rhabdomyolysis with acute renal failure we performed a combined treatment of hemoadsorption using a Cytosorb hemoadsorber and continuous venovenous hemodialysis (CVVHD). Subsequently the patient recovered and was discharged home with no signs of infections and with normal renal function. Conclusion. We present a case of pyelonephritis with nontraumatic renal rupture leading to necrotizing fasciitis with osteomyelitis of the lower limb. The early treatment of the patient with a Cytosorb hemoadsorber led to a rapid hemodynamic and metabolic stabilization and preservation of the renal function, suggesting that hemoadsorption might be a rescue therapy in patients with severe septic shock and traumatic rhabdomyolysis.

scholarly journals Effects of norepinephrine on hemodynamics, vascular elasticity, cardiac pump function, and inflammatory factors in patients with septic shock

2019 ◽  
Vol 17 ◽  
pp. 205873921983839
Author(s):  
Fengzhi Wang ◽  
Mancui Zhang ◽  
Xiujuan Wang ◽  
Xiaopeng Zhong ◽  
Po Ding
Keyword(s):  
Septic Shock ◽  
Blood Vessel ◽  
Inflammatory Factors ◽  
Control Group ◽  
Pump Function ◽  
Heart Pump ◽  
Cardiac Pump Function ◽  
Vascular Elasticity ◽  
Experimental Group ◽  
Severe Septic Shock

The effects of norepinephrine on hemodynamics, vascular elasticity, cardiac pump function, and inflammatory factors in patients with septic shock remained unknown. In this study, we included 124 cases of severe septic shock patients in our hospital. The patients were randomly divided into control group (treated with dopamine) and experimental group (treated with dopamine plus norepinephrine), while the hemodynamic index (heart rate (HR)), blood vessel elasticity index, heart pump function, and inflammatory factor index were recorded. After 12 h of treatment, both groups showed decreased HR, increased levels of cardiac index (CI), mean arterial pressure (MAP), central venous pressure (CVP), peripheral vascular resistance index (PVRI), and vascular elasticity ( P < 0.05). To date, lower HR, higher levels of CI, MAP, CVP, and PVRI were observed in the experimental group ( P < 0.05). Furthermore, the vascular elastic coefficient, stiffness index, arterial compliance, and the precursors of plasma amino-terminal brain natriuretic peptide were also significantly higher in the experimental group than those in the control group ( P < 0.05). However, inflammatory cell tumor necrosis factor alpha factor test group (TNF alpha), interleukin-1 (IL-1), and interleukin-6 (IL-6) concentrations were significantly lower than the control group ( P < 0.05), compared to experimental group ( P < 0.05). This research indicates that phenylephrine could significantly improve hemodynamics in patients with severe septic shock, by maintaining blood vessel elasticity, improving heart pump function, and reducing the inflammatory factors’ activities, and this method could be used as a line of vascular tension of the medications used in patients with septic shock.

Increasing mean arterial pressure in patients with septic shock: effects on oxygen variables and renal function

2005 ◽  
Vol 22 (Supplement 34) ◽  
pp. 177
Author(s):  
M. Leone ◽  
J. Albanèse ◽  
I. Boyadjev ◽  
F. Antonini ◽  
C. Martin
Keyword(s):  
Septic Shock ◽  
Renal Function ◽  
Mean Arterial Pressure ◽  
Arterial Pressure

scholarly journals Effect of dopamine and metaraminol on the renal function of patients with septic shock

2007 ◽  
Vol 120 (8) ◽  
pp. 680-683 ◽  
Author(s):  
Li-chao HOU ◽  
Shu-zhi LI ◽  
Li-ze XIONG ◽  
Shao-yang CHEN ◽  
Min CHEN ◽  
...  
Keyword(s):  
Septic Shock ◽  
Renal Function

scholarly journals An Innovative Approach for The Integration of Proteomics and Metabolomics Data In Severe Septic Shock Patients Stratified for Mortality

2018 ◽  
Vol 8 (1) ◽  
Author(s):  
Alice Cambiaghi ◽  
Ramón Díaz ◽  
Julia Bauzá Martinez ◽  
Antonia Odena ◽  
Laura Brunelli ◽  
...  
Keyword(s):  
Septic Shock ◽  
Innovative Approach ◽  
Metabolomics Data ◽  
Severe Septic Shock

Successful Treatment With Continuous Enteral Protease Inhibitor in a Patient With Severe Septic Shock

2012 ◽  
Vol 44 (3) ◽  
pp. 817-819 ◽  
Author(s):  
Y.-T. Lee ◽  
J. Wei ◽  
Y.-C. Chuang ◽  
C.-Y. Chang ◽  
I.-C. Chen ◽  
...  
Keyword(s):  
Septic Shock ◽  
Protease Inhibitor ◽  
Successful Treatment ◽  
Severe Septic Shock

Does Vasopressin Infusion Improve the Outcome of Severe Septic-Shock without any Adverse Effects?

2003 ◽  
Vol 98 (3) ◽  
pp. 793-793
Author(s):  
Bhavesh M. Patel ◽  
Dean R. Chittock ◽  
James A. Russell ◽  
Keith R. Walley
Keyword(s):  
Septic Shock ◽  
Adverse Effects ◽  
Vasopressin Infusion ◽  
Severe Septic Shock

654: Disseminated Strongyloidiasis Hyperinfection Syndrome With Severe Septic Shock

2020 ◽  
Vol 49 (1) ◽  
pp. 322-322
Author(s):  
Brandon Lui ◽  
George Nasr ◽  
Antonio Beltran ◽  
Sindalisa Hean ◽  
Twinkle Chandak ◽  
...  
Keyword(s):  
Septic Shock ◽  
Hyperinfection Syndrome ◽  
Disseminated Strongyloidiasis ◽  
Severe Septic Shock

THE EFFECTS OF FENOLDOPAM ON RENAL FUNCTION AND METABOLISM IN AN OVINE MODEL OF SEPTIC SHOCK

Shock ◽  
2016 ◽  
Vol 45 (4) ◽  
pp. 385-392 ◽  
Author(s):  
Emiel Hendrik Post ◽  
Fuhong Su ◽  
Fabio Silvio Taccone ◽  
Koji Hosokawa ◽  
Antoine Herpain ◽  
...  
Keyword(s):  
Septic Shock ◽  
Renal Function ◽  
Ovine Model
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