The incidence of rubella virus infections in Switzerland after the introduction of the MMR mass vaccination programme

1995 ◽  
Vol 11 (3) ◽  
pp. 305-310 ◽  
Author(s):  
Lukas Matter ◽  
Frank Bally ◽  
Daniel Germann ◽  
Kurt Schopfer
2021 ◽  
Vol 23 (3) ◽  
pp. 1-2
Author(s):  
Linda Nazarko

Care homes have been first in line when it comes to the COVID-19 vaccination programme, but there is some concern among staff and residents about the vaccine’s efficacy and safety. In her role as clinical lead for a mass vaccination centre in London, Linda Nazarko provides assurance and urges any reluctant care staff to consider resident safety.


1975 ◽  
Vol 21 (3) ◽  
pp. 289-292 ◽  
Author(s):  
Pierre Payment ◽  
Lucille Roy ◽  
Jean-Claude Gilker ◽  
André Chagnon

Vero cells were more suitable then BHK-21 cells for the detection of rubella-specific 1gG antibodies because the nonspecific fluorescence was minimal. However, BHK-21 cells were found more sensitive than Vero cells for the detection of rubella-specific IgM antibodies.


Brain ◽  
1975 ◽  
Vol 98 (4) ◽  
pp. 583-594 ◽  
Author(s):  
J. H. CONNOLLY ◽  
W. M. HUTCHINSON ◽  
INGRID V. ALLEN ◽  
J. A. LYTTLE ◽  
M. W. SWALLOW ◽  
...  

2007 ◽  
Vol 14 (11) ◽  
pp. 1416-1419 ◽  
Author(s):  
Christelle Vauloup-Fellous ◽  
Jessica Ursulet-Diser ◽  
Liliane Grangeot-Keros

ABSTRACT We describe here a rapid and semiautomated method for the determination of rubella virus immunoglobulin G (IgG) avidity with the VIDAS instrument. A total of 153 serum samples from persons with naturally acquired rubella virus infections (n = 98), from vaccinated persons (n = 44), and from patients with autoantibodies (n = 11) were included in this study. The rubella virus-specific IgG avidity assay we developed for the VIDAS instrument was evaluated by comparison with an in-house method. Results obtained with the VIDAS instrument allow considering this method valuable to help confirm or exclude acute primary infection or recent vaccination.


1988 ◽  
Vol 16 (3) ◽  
pp. 129-135 ◽  
Author(s):  
Karin Fahlgren

A review has been done of the available literature on measles, mumps, rubella and vaccines against these diseases. So far, 17 studies on the same virus strains as those in M-M-R II have been published. The rate of seroconversion is practically 100% for rubella, generally more than 90% for measles and between 40 and 100% for mumps. Immediate side effects of vaccinaton are mild in infants and negligible in schoolchildren. However, the follow-up periods are short. In the only 10-year follow-up published, 14 subjects remained at the end of the period, and the vaccine studied differed from M-M-R II. Large, well-documented studies of MMR vaccination in unselected populations are rare. It must be of crucial importance that the immunity situation is followed up continuously for both vaccinated and non-vaccinated individuals when a mass vaccination programme has been introduced as there will be a risk of outbreaks of diseases mostly among young adults.


Vaccine ◽  
1985 ◽  
Vol 3 (2) ◽  
pp. 113-116 ◽  
Author(s):  
Margareta Böttiger ◽  
Brith Christenson ◽  
John Taranger ◽  
Mona Bergman

2021 ◽  
Author(s):  
Shangkun ou ◽  
Yi Mao ◽  
Sijie Lin ◽  
Chengfang Zhu ◽  
Xiaodong Liu ◽  
...  

Abstract This retrospective study aimed to determine the correlation between cytokine levels and virus status in the aqueous humor of 38 patients with Fuchs heterochromic iridocyclitis (FHI) with/without viral presence between May 2017 and January 2020. The levels of cytokines were analyzed in the groups with and without virus-related FHI. Among the patients, 50% had rubella virus, 5.26% had cytomegalovirus, and 2.63% had herpes simplex virus infections. The expression of interleukin-6 (IL-6) and IL-8 was significantly higher and that of basic fibroblast growth factor (bFGF) was significantly lower in the virus-positive group than in the virus-negative group (P = 0.015, P = 0.001, and P = 0.001, respectively). Although there was no significant difference in the mean expression of vascular cell adhesion protein 1 (VCAM-1), IL-10, and vascular endothelial growth factor (VEGF), those of VCAM-1 and IL-10 were higher (M = 1338, M = 1390, respectively; M = 6.225 and 10.600, respectively) and that of VEGF was lower (M = 134.5, M = 38.70, respectively) in the virus-positive group than in the virus-negative group. Similar findings were observed for the expressions of IL-6, IL-8, and bFGF in the rubella-positive and -negative groups. Viral presence was highly related to FHI, especially that of the rubella virus. High levels of inflammatory cytokines and low levels of neovascularization-related factors are involved in rubella-related FHI. These study findings could be helpful in the diagnosis and treatment of FHI.


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