Lung lavage with a saline volume similar to functional residual capacity followed by surfactant administration in newborns with severe meconium aspiration syndrome

1996 ◽  
Vol 22 (12) ◽  
pp. 1412-1413 ◽  
Author(s):  
F. Mosca ◽  
M. Colnaghi ◽  
F. Castoldi
Keyword(s):  
Functional Residual Capacity ◽  
Lung Lavage ◽  
Meconium Aspiration Syndrome ◽  
Meconium Aspiration ◽  
Residual Capacity ◽  
Surfactant Administration

scholarly journals Therapeutic Lung Lavage with Diluted Surfactant in Neonates with Severe Meconium Aspiration Syndrome

2008 ◽  
Vol 71 (2) ◽  
pp. 103-109 ◽  
Author(s):  
Chiao-Wei Lo ◽  
Mei-Jy Jeng ◽  
Feng-Yu Chang ◽  
Ja-Fang Yang ◽  
Yu-Sheng Lee ◽  
...  
Keyword(s):  
Lung Lavage ◽  
Meconium Aspiration Syndrome ◽  
Meconium Aspiration

Therapeutic lung lavage in meconium aspiration syndrome: A preliminary report

2007 ◽  
Vol 43 (7-8) ◽  
pp. 539-545 ◽  
Author(s):  
Peter A Dargaville ◽  
John F Mills ◽  
Beverley Copnell ◽  
Peter M Loughnan ◽  
Peter N McDougall ◽  
...  
Keyword(s):  
Preliminary Report ◽  
Lung Lavage ◽  
Meconium Aspiration Syndrome ◽  
Meconium Aspiration

Fluid recovery during lung lavage in meconium aspiration syndrome

2012 ◽  
Vol 102 (2) ◽  
pp. e90-e93 ◽  
Author(s):  
Peter A Dargaville ◽  
Beverley Copnell ◽  
John F Mills ◽  
Ismail Haron ◽  
Jimmy KF Lee ◽  
...  
Keyword(s):  
Lung Lavage ◽  
Meconium Aspiration Syndrome ◽  
Meconium Aspiration

Surfactant therapy for meconium aspiration syndrome in neonates: a systematic overview of systematic reviews and recent clinical trials

2020 ◽  
Vol 9 (8) ◽  
pp. 527-536
Author(s):  
Mohammed Ahmed Abdelaal ◽  
Dina Abushanab ◽  
Daoud Al-Badriyeh
Keyword(s):  
Clinical Trials ◽  
Systematic Reviews ◽  
Lung Lavage ◽  
Meconium Aspiration Syndrome ◽  
Risk Of Bias ◽  
Surfactant Therapy ◽  
High Quality ◽  
Meconium Aspiration ◽  
Systematic Overview ◽  
Overview Of Systematic Reviews

Aim: To conduct a systematic overview of systematic reviews (SRs) and randomized clinical trials (RCTs) on surfactant therapy in neonatal meconium aspiration syndrome. Methods: We searched EMBASE, PROQUEST and PubMed to summarize the different effects of surfactant lung lavage and bolus surfactant therapies in neonates with meconium aspiration syndrome. Results: With a total of 1377 patients, three SRs and two RCTs were included in analysis. Surfactant effectiveness was concluded by low-quality SRs, with high risk of bias, which was contradicted by high-quality SRs, with low risk of bias. In SRs, the surfactant lung lavage reduced mortality, need for extracorporeal membrane oxygenation and hospitalization, while the bolus surfactant did not. In recent high-quality RCTs, however, the two modalities did not significantly differ. Conclusion: The evidence on surfactant effectiveness and its method of administration is sparse and inconsistent.

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