3D TOF MRA: role in evaluation of intracranial aneurysms following embolization with platinum coils

1994 ◽  
Vol 2 (3) ◽  
pp. 327-334 ◽  
Author(s):  
D. J. Wilcock ◽  
T. Jaspan ◽  
S. Evans
Keyword(s):  
Intracranial Aneurysms ◽  
Tof Mra ◽  
Platinum Coils

scholarly journals In vitro and in vivo Studies of the Extent of Electrothrombotic Deposition of Blood Elements on the Surface of Electrolytically Detachable Coils

2004 ◽  
Vol 10 (3) ◽  
pp. 189-201 ◽  
Author(s):  
H. Henkes ◽  
S. Brew ◽  
S. Felber ◽  
E. Miloslavski ◽  
G. Mogilevski ◽  
...  
Keyword(s):  
Endovascular Treatment ◽  
Intravenous Administration ◽  
Direct Current ◽  
Intracranial Aneurysms ◽  
Thrombus Formation ◽  
Applied Current ◽  
Detachable Coils ◽  
Platinum Coils

Endovascular treatment of intracranial aneurysms with electrolytically detachable coils is often claimed to be based on electrothrombosis, i.e. intra-aneurysmal thrombus formation through applied direct current. Despite the fact that this concept was described more than a century ago, the significance of electrothrombosis in the endovascular treatment of aneurysms remains debatable. Apart from electrothrombosis, mechanical obliteration of the aneurysmal lumen might be one of the many possible mechanisms to explain why and how detachable coils are effective in preventing aneurysms from (re-)rupture. The purpose of this experimental study was to investigate to what extent direct current comparable to that used for coil detachment would influence the adhesion of cellular and liquid blood components to the surface of electrolytically detachable platinum coils. For the in vitro study, electrolytically detachable platinum coils of various types were exposed to stagnant heparinised blood for a total of 16 h, without or with applied direct current for 30 or 90 s (1 mA, 4–6 V, coil as anode). For the in vivo study, electrolytically detachable platinum coils were exposed to flowing blood for 180 s, without or with applied direct current (2 mA, 4–6 V, coil as either anode or cathode), without anti-coagulation and after intravenous administration of 5000 U Heparin and again after the intravenous administration of 500 mg Aspisol in addition to Heparin. After exposure to blood according to these different experimental protocols, the coils were fixed in formalin solution, gold coated and examined by scanning electron microscopy. Thrombus formation on the surface of all unfibred coils was thin and highly variable both from coil to coil, and on different areas of any given coil. The application of direct current minimally enhanced thrombus formation in stagnant blood in vitro, but not in vivo. The cellular and fibrin adhesions on the coil surfaces without and with applied current did not effectively increase the diameter or volume of unfibred coils. Coils with attached nylon fibres, however, proved to be highly thrombogenic without or with application of current. In fibred coils, surface adhesions without and with applied current were voluminous enough to effectively increase the diameter of the coil, potentially important for the process of endosaccular aneurysm occlusion. Electrothrombosis plays no role in the endovascular treatment of intracranial aneurysms with electrolytically detachable coils. This explains why platinum coils with non-electrolytic detachment mechanisms show a similar efficiency and recurrence rate.

scholarly journals Deep Learning–Based Detection of Intracranial Aneurysms in 3D TOF-MRA

2018 ◽  
Vol 40 (1) ◽  
pp. 25-32 ◽  
Author(s):  
T. Sichtermann ◽  
A. Faron ◽  
R. Sijben ◽  
N. Teichert ◽  
J. Freiherr ◽  
...  
Keyword(s):  
Deep Learning ◽  
Intracranial Aneurysms ◽  
Tof Mra

Single-center Comparison of Bioactive versus Bare Platinum Coils for the Endovascular Treatment of Intracranial Aneurysms

Neurosurgery ◽  
2008 ◽  
Vol 62 (6) ◽  
pp. 1405
Author(s):  
Michelle J. Smith ◽  
Kyle Chapple ◽  
Justin Mascitelli ◽  
Philip E. Stieg ◽  
Howard A. Riina ◽  
...  
Keyword(s):  
Endovascular Treatment ◽  
Intracranial Aneurysms ◽  
Single Center ◽  
Bare Platinum Coils ◽  
Platinum Coils

Selective endovascular treatment of 71 intracranial aneurysms with platinum coils

1993 ◽  
Vol 79 (1) ◽  
pp. 3-10 ◽  
Author(s):  
Alfredo E. Casasco ◽  
Armand Aymard ◽  
Y. Pierre Gobin ◽  
Emmanuel Houdart ◽  
André Rogopoulos ◽  
...  
Keyword(s):  
Intracranial Aneurysms ◽  
Mortality Rates ◽  
Posterior Circulation ◽  
Endovascular Techniques ◽  
Anterior Circulation ◽  
Content Type ◽  
Grade Ii ◽  
Platinum Coils ◽  
Type Of Surgery

✓ Seventy-one intracranial aneurysms were treated by endovascular techniques, with the placement of minicoils inside the aneurysmal sac. Most aneurysms were manifest by hemorrhage (67 cases), and 43 of these were treated within the first 3 days after presentation. At the 1-year follow-up examination, the outcome was scored as good in 84.5% of cases, but the morbidity and mortality rates were 4.2% and 11.3%, respectively. Twenty-nine aneurysms in the anterior circulation and 42 in the posterior circulation were treated. In this series, 23 patients were classified as Hunt and Hess neurological Grade I, 27 as Grade II, 12 as Grade III, nine as Grade IV, and none as Grade V. Thirty-three aneurysms were less than 10 mm in diameter, 28 were 10 to 25 mm, and 10 were larger than 25 mm. The preliminary results from this study appear to justify the emergency treatment of aneurysms by this approach. Aneurysms in the posterior circulation are particularly well suited for this type of surgery.

scholarly journals The Role of 3 Tesla MRA in the Detection of Intracranial Aneurysms

2012 ◽  
Vol 2012 ◽  
pp. 1-9 ◽  
Author(s):  
Eftychia Z. Kapsalaki ◽  
Christos D. Rountas ◽  
Kostas N. Fountas
Keyword(s):  
Magnetic Field ◽  
Intracranial Aneurysms ◽  
Flow Characteristics ◽  
Imaging Method ◽  
Digital Subtraction ◽  
Prompt Treatment ◽  
Tof Mra ◽  
Contrast Enhanced ◽  
Erroneous Interpretation

Intracranial aneurysms constitute a common pathological entity, affecting approximately 1–8% of the general population. Their early detection is essential for their prompt treatment. Digital subtraction angiography is considered the imaging method of choice. However, other noninvasive methodologies such as CTA and MRA have been employed in the investigation of patients with suspected aneurysms. MRA is a noninvasive angiographic modality requiring no radiation exposure. However, its sensitivity and diagnostic accuracy were initially inadequate. Several MRA techniques have been developed for overcoming all these drawbacks and for improving its sensitivity. 3D TOF MRA and contrast-enhanced MRA are the most commonly employed techniques. The introduction of 3 T magnetic field further increased MRA's sensitivity, allowing detection of aneurysms smaller than 3 mm. The development of newer MRA techniques may provide valuable information regarding the flow characteristics of an aneurysm. Meticulous knowledge of MRA's limitations and pitfalls is of paramount importance for avoiding any erroneous interpretation of its findings.

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