Acute toxicities of selected heavy metals to the softshell clam,Mya arenaria

1977 ◽  
Vol 17 (2) ◽  
pp. 137-145 ◽  
Author(s):  
Ronald Eisler
2021 ◽  
Vol 28 (2) ◽  
Author(s):  
Paul Geoghegan ◽  
Jamie O'Brien ◽  
Charles W. Walker ◽  
MacKenzie Heagy ◽  
S. Anne Böttger

2020 ◽  
Vol 12 (10) ◽  
pp. 1681-1693
Author(s):  
David C Plachetzki ◽  
M Sabrina Pankey ◽  
Matthew D MacManes ◽  
Michael P Lesser ◽  
Charles W Walker

Abstract Apoptosis is a fundamental feature of multicellular animals and is best understood in mammals, flies, and nematodes, with the invertebrate models being thought to represent a condition of ancestral simplicity. However, the existence of a leukemia-like cancer in the softshell clam Mya arenaria provides an opportunity to re-evaluate the evolution of the genetic machinery of apoptosis. Here, we report the whole-genome sequence for M. arenaria which we leverage with existing data to test evolutionary hypotheses on the origins of apoptosis in animals. We show that the ancestral bilaterian p53 locus, a master regulator of apoptosis, possessed a complex domain structure, in contrast to that of extant ecdysozoan p53s. Further, ecdysozoan taxa, but not chordates or lophotrochozoans like M. arenaria, show a widespread reduction in apoptosis gene copy number. Finally, phylogenetic exploration of apoptosis gene copy number reveals a striking linkage with p53 domain complexity across species. Our results challenge the current understanding of the evolution of apoptosis and highlight the ancestral complexity of the bilaterian apoptotic tool kit and its subsequent dismantlement during the ecdysozoan radiation.


2006 ◽  
Vol 84 (3) ◽  
pp. 459-472 ◽  
Author(s):  
Sophie LeBlanc ◽  
Gilles Miron

We examined the settlement and recruitment of the softshell clam (Mya arenaria L., 1758) in two tidally contrasted regimes in eastern Canada. The Bay of Fundy (strong tides) and the Northumberland Strait (weak tides) were used to describe the distribution of planktonic larvae and early settlers. These distributions were compared with those of juvenile and adult forms observed in the same intertidal habitats. Results showed that the abundances of planktonic stages were the same at all tidal levels except in one site of the Bay of Fundy. Early settlers varied according to a site × intertidal level interaction. Juveniles and adults also varied according to a similar interaction, most being in the upper intertidal level. Simple linear regressions demonstrated that no relationship exists between the number of planktonic larvae and the number of early settlers. The only significant relationship observed was the one between the number of juveniles (1–5 mm size class) and the number of adults in one of the Northumberland Strait sites. Our results show, through the high spatial resolution and wide range of spatial scales covered by the study, that the dominant regional tidal regime does not have an effect on the distribution of the softshell clam. Local hydrodynamic effects appear to drive the intertidal distribution of the softshell clam life-cycle stages.


Toxicology ◽  
1999 ◽  
Vol 142 (2) ◽  
pp. 145-156 ◽  
Author(s):  
P Brousseau ◽  
J Pellerin ◽  
Y Morin ◽  
D Cyr ◽  
B Blakley ◽  
...  

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