Crystal structures and physical chemical properties of nedocromil zinc heptahydrate and nedocromil magnesium pentahydrate

1996 ◽  
Vol 26 (3) ◽  
pp. 167-178 ◽  
Author(s):  
William H. Ojala ◽  
Rajendra K. Khankari ◽  
David J. W. Grant ◽  
William B. Gleason
Author(s):  
Konstadina Dalacosta ◽  
Evangelia. A. Pavlatou

In chemical engineering, undergraduate students often have to face the highly demanding process of understanding concepts from the microscopic level (e.g., ionic crystals such as zinc sulphide or covalent lattice crystals diamond, graphite, graphene etc.) and then explain with certain physical–chemical properties their macroscopic behaviour. Therefore, the main idea was to construct a specifically designed educational material that focusses on the benefits of viewing visualisations to enhance students’ conceptual understanding of solids and crystal structures augmented by cartoons, and evaluate its usability. The interactive ‘cartoons’ agents were developed from scratch, giving them freedom of movement and realism at the same time. A research was conducted in the School of Chemical Engineering in Greece (National Technical University of Athens), evaluated the usability of the digital material and the contribution of the 3-D visualisations and the cartoons agents in the understanding of such high-cognitive load concepts.Keywords: Cartoons, 3-D visualisations, crystal structures, chemical engineering.


2014 ◽  
Vol 70 (a1) ◽  
pp. C1808-C1808 ◽  
Author(s):  
Kelly Lixandrão ◽  
Fabio Ferreira

Drugs may present polycrystalline polymorphism (property of a substance to crystallize in more than one form or crystal structure). These variations can cause changes in physical-chemical properties and differences between the polymorphs as shape, solubility, density, melting range, among other consequences, leading to formulations that are not effective, although the chemical formula is the same [1]. Drugs such as albendazole (C12H15N3O2S, which is one of the most effective anthelmintics, [2] showing activity against nematodes, trematodes and cestodes, reasons that added to its safety and low cost have made it a drug widely used in human medicine and veterinary), has more than two different crystal structures, and only two of them are known. The X-ray powder diffraction is a powerful technique used in the structural characterization of drugs, and coupled with the Rietveld method [4], the quantification of the active phases, through the knowledge of their crystal structures, becomes possible. In this paper we discuss results on the differences between the polymorphs of albendazole, with data obtained by means of X-ray diffraction, thermal analysis (differential scanning calorimetry and thermogravimetric analysis), Fourier transform infrared spectroscopy and scanning electron microscopy.


2014 ◽  
Vol 7 (9) ◽  
pp. 2900-2924 ◽  
Author(s):  
Li-Dong Zhao ◽  
Jiaqing He ◽  
David Berardan ◽  
Yuanhua Lin ◽  
Jing-Feng Li ◽  
...  

This review summarizes the crystal structures, microstructures, electronic structures, physical/chemical properties, and effective methods to enhance the thermoelectric performance of the BiCuSeO system.


1986 ◽  
Vol 21 (3) ◽  
pp. 344-350 ◽  
Author(s):  
Barry G. Oliver ◽  
Klaus L.E. Kaiser

Abstract The concent rat ions of hexachloroethane (HCE), hexachlorobutadiene (HCBD), pentachlorobenzene (QCB), hexachlorobenzene (HCB) and octachlorostyrene (OCS) in large volume water samples show that the major sources of these chemicals to the St. Clair River are Dow Chemical Company effluents and, to a lesser degree, Sarnia’s Township ditch which drains one of Dow’s waste disposal sites. Tributaries entering the river on both sides of the Canada/United States border contain measurable concentrations of these chemicals indicating low level contamination throughout the area. The degree of water/suspended sediment partitioning of the chemicals (Kp) was studied. Kp values for the individual chemicals changed in a manner consistent with changes in their physical-chemical properties.


2020 ◽  
Vol 20 (11) ◽  
pp. 1340-1351 ◽  
Author(s):  
Ponnurengam M. Sivakumar ◽  
Matin Islami ◽  
Ali Zarrabi ◽  
Arezoo Khosravi ◽  
Shohreh Peimanfard

Background and objective: Graphene-based nanomaterials have received increasing attention due to their unique physical-chemical properties including two-dimensional planar structure, large surface area, chemical and mechanical stability, superconductivity and good biocompatibility. On the other hand, graphene-based nanomaterials have been explored as theranostics agents, the combination of therapeutics and diagnostics. In recent years, grafting hydrophilic polymer moieties have been introduced as an efficient approach to improve the properties of graphene-based nanomaterials and obtain new nanoassemblies for cancer therapy. Methods and results: This review would illustrate biodistribution, cellular uptake and toxicity of polymergraphene nanoassemblies and summarize part of successes achieved in cancer treatment using such nanoassemblies. Conclusion: The observations showed successful targeting functionality of the polymer-GO conjugations and demonstrated a reduction of the side effects of anti-cancer drugs for normal tissues.


2021 ◽  
Vol 11 (10) ◽  
pp. 4417
Author(s):  
Veronica Vendramin ◽  
Gaia Spinato ◽  
Simone Vincenzi

Chitosan is a chitin-derived fiber, extracted from the shellfish shells, a by-product of the fish industry, or from fungi grown in bioreactors. In oenology, it is used for the control of Brettanomyces spp., for the prevention of ferric, copper, and protein casse and for clarification. The International Organisation of Vine and Wine established the exclusive utilization of fungal chitosan to avoid the eventuality of allergic reactions. This work focuses on the differences between two chitosan categories, fungal and animal chitosan, characterizing several samples in terms of chitin content and degree of deacetylation. In addition, different acids were used to dissolve chitosans, and their effect on viscosity and on the efficacy in wine clarification were observed. The results demonstrated that even if fungal and animal chitosans shared similar chemical properties (deacetylation degree and chitin content), they showed different viscosity depending on their molecular weight but also on the acid used to dissolve them. A significant difference was discovered on their fining properties, as animal chitosans showed a faster and greater sedimentation compared to the fungal ones, independently from the acid used for their dissolution. This suggests that physical–chemical differences in the molecular structure occur between the two chitosan categories and that this significantly affects their technologic (oenological) properties.


2020 ◽  
Vol 59 (1) ◽  
pp. 441-454
Author(s):  
Carlos A. Martínez-Pérez

AbstractIn the last years, electrospinning has become a technique of intense research to design and fabricate drug delivery systems (DDS), during this time a vast variety of DDS with mainly electrospun polymers and many different active ingredient(s) have been developed, many intrinsic and extrinsic factor have influence in the final system, there are those that can be attributed to the equipment set up and that to the physical-chemical properties of the used materials in the fabrication of DDS. After all, this intense research has generated a great amount of DDS loaded with one or more drugs. In this manuscript a review with the highlights of different kind of systems for drug delivery systems is presented, it includes the basic concepts of electrospinning, types of equipment set up, polymer/drug systems, limitations and challenges that need to be overcome for clinical applications.


2021 ◽  
Vol 494 ◽  
pp. 119334
Author(s):  
Vinicius Evangelista Silva ◽  
Thiago Assis Rodrigues Nogueira ◽  
Cassio Hamilton Abreu-Junior ◽  
Arun Dilipkumar Jani ◽  
Salatier Buzetti ◽  
...  

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