Role of surgical treatment for recurrent hepatocellular carcinoma after hepatic resection

1993 ◽  
Vol 17 (6) ◽  
pp. 792-795 ◽  
Author(s):  
Yasuaki Nakajima ◽  
Takashi Ohmura ◽  
Jun Kimura ◽  
Tsuyoshi Shimamura ◽  
Kazuhito Misawa ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Surgical Treatment ◽  
Hepatic Resection ◽  
Recurrent Hepatocellular Carcinoma

scholarly journals Studies on multidisciplinary therapy for recurrent hepatocellular carcinoma after hepatic resection.

1989 ◽  
Vol 22 (3) ◽  
pp. 779-783 ◽  
Author(s):  
Atsuhiko MAKI ◽  
Takashi TAKAYASU ◽  
Keiichiro MORI ◽  
Yasuyuki SHIMAHARA ◽  
Yoshio YAMAOKA ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Hepatic Resection ◽  
Multidisciplinary Therapy ◽  
Recurrent Hepatocellular Carcinoma

Defining Optimal Surgical Treatment for Recurrent Hepatocellular Carcinoma: A Propensity Score Matched Analysis

2018 ◽  
Vol 24 (8) ◽  
pp. 1062-1069 ◽  
Author(s):  
Ka Wing Ma ◽  
Kenneth Siu Ho Chok ◽  
Wong Hoi She ◽  
Albert Chi Yan Chan ◽  
Tan To Cheung ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Surgical Treatment ◽  
Propensity Score ◽  
Recurrent Hepatocellular Carcinoma

scholarly journals Radiofrequency ablation versus hepatic resection for recurrent hepatocellular carcinoma: an updated meta-analysis

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Daopeng Yang ◽  
Bowen Zhuang ◽  
Yan Wang ◽  
Xiaoyan Xie ◽  
Xiaohua Xie
Keyword(s):  
Hepatocellular Carcinoma ◽  
Radiofrequency Ablation ◽  
Hepatic Resection ◽  
Fixed Effects ◽  
Meta Analysis ◽  
Cochrane Library ◽  
Recurrent Hepatocellular Carcinoma ◽  
Major Complications ◽  
Alternative Treatment Option ◽  
Significant Difference

Abstract Background The clinical benefits of treatment with radiofrequency ablation (RFA) and repeat hepatic resection (RHR) for recurrent hepatocellular carcinoma (RHCC) remain controversial. This meta-analysis aims to evaluate the outcomes and major complications of RFA versus RHR in patients with early-stage RHCC. Methods PubMed, Embase, Web of Science and the Cochrane Library were systematically searched for comparative studies on the evaluation of RHR versus RFA for RHCC. The primary outcome was overall survival (OS), and the secondary outcomes were progression-free survival (PFS) and major complications. Meta-analysis was performed using a random-effects model or fixed-effects model, and heterogeneity was tested by the Cochran Q statistic. Results Ten studies with 1612 patients (RHR = 654, RFA = 958) were included in the meta-analysis. The meta-analysis showed that RHR had superior OS (HR 0.77, 95% CI =0.65–0.92, P = 0.004) and PFS (HR 0.81, 95% CI =0.67–0.98, P = 0.027) compared to RFA, whereas major complications may be less frequent in the RFA group (OR 0.15, 95% CI = 0.06–0.39, P < 0.001). In the subgroup analysis of patients with single RHCC ≤3 cm, OS (HR 1.03, 95% CI =0.69–1.52, P = 0.897) and PFS (HR 0.99, 95% CI = 0.71–1.37, P = 0.929) showed no significant differences in the comparison of RHR and RFA. In single RHCC> 3 cm and ≤ 5 cm, RFA showed an increased mortality in terms of OS (HR 0.57, 95% CI = 0.37–0.89, P = 0.014). Conclusion RHR offers a longer OS and PFS than RFA for patients with RHCC, but no statistically significant difference was observed for single RHCC ≤3 cm. The advantages of fewer major complications may render RFA an alternative treatment option for selected patients.

Hepatic Resection for “BCLC Stage A” Hepatocellular Carcinoma. The Prognostic Role of Alpha-Fetoprotein

2011 ◽  
Vol 19 (2) ◽  
pp. 426-434 ◽  
Author(s):  
Roberto Santambrogio ◽  
Enrico Opocher ◽  
Mara Costa ◽  
Matteo Barabino ◽  
Massimo Zuin ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Hepatic Resection ◽  
Alpha Fetoprotein ◽  
Prognostic Role

Aggressive surgical treatment for recurrent hepatocellular carcinoma

2003 ◽  
Vol 124 (4) ◽  
pp. A98
Author(s):  
Akira Kobayashi ◽  
Shinichi Miyagawa ◽  
Akimasa Matsushita ◽  
Takenari Nakata ◽  
Kazuhiko Nomura ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Surgical Treatment ◽  
Recurrent Hepatocellular Carcinoma
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