Radical resection and liver grafting as the two main components of surgical strategy in the treatment of proximal bile duct cancer

1988 ◽  
Vol 12 (1) ◽  
pp. 68-77 ◽  
Author(s):  
Rudolf Pichlmayr ◽  
Burckhardt Ringe ◽  
Werner Lauchart ◽  
Wolf O. Bechstein ◽  
Gundolf Gubernatis ◽  
...  
Keyword(s):  
Bile Duct ◽  
Bile Duct Cancer ◽  
Radical Resection ◽  
Surgical Strategy ◽  
Duct Cancer ◽  
Main Components ◽  
Proximal Bile Duct

scholarly journals Experience With Radical Resection in The Management of Proximal Bile Duct Cancer

HPB Surgery ◽  
1989 ◽  
Vol 1 (4) ◽  
pp. 297-307 ◽  
Author(s):  
Jean C. Emond ◽  
James T. Mayes ◽  
Dale A. Rouch ◽  
J. Richard Thistlethwaite ◽  
Christoph E. Broelsch
Keyword(s):  
Bile Duct ◽  
Bile Duct Cancer ◽  
Clinical Symptoms ◽  
Disease Free Survival ◽  
Radical Resection ◽  
University Center ◽  
Aggressive Surgical Approach ◽  
Surgical Cure ◽  
Duct Cancer ◽  
Proximal Bile Duct

Multiple surgical and nonsurgical approaches have been advocated for the treatment of proximal bile duct cancer. However, survival appears longest when a resection can be performed. Fifteen patients treated at a university center were managed with an aggressive surgical approach. Resection of the tumor was performed in 13 of 15 patients (87%). Of the patients undergoing resection, major hepatic resection was performed in 8 (62%), while excision of vessels with reconstruction was performed in 5 (38%). Eleven of the 13 resected patients (85%) were discharged from the hospital. Clinical symptoms of recurrent disease occurred between 3 and 36 months after surgery in 7 patients, 6 of whom have died. Three other patients are alive at 5, 21, and 36 months without clinical evidence of recurrence. There was no correlation between the completeness of resection and the duration of disease-free survival.These results demonstrate that radical resection of high bile duct tumors can be accomplished with an acceptable early mortality rate, thereby extending the benefits of resection to a higher proportion of patients. While resection is clearly effective at controlling local disease and providing palliation of jaundice, surgical cure remains exceptional. Further improvement in the therapy of bile duct cancer must await development of more effective multi-modality approaches.

Proximal Bile Duct Cancer

2006 ◽  
pp. 298-305
Author(s):  
J. Lawrence Munson
Keyword(s):  
Bile Duct ◽  
Bile Duct Cancer ◽  
Duct Cancer ◽  
Proximal Bile Duct

scholarly journals Strategies in proximal bile duct cancer

1983 ◽  
Vol 85 (2) ◽  
pp. 479-480
Author(s):  
R.Scott Jones
Keyword(s):  
Bile Duct ◽  
Bile Duct Cancer ◽  
Duct Cancer ◽  
Proximal Bile Duct

scholarly journals Is Aggressive Surgical Palliation of Proximal Bile Duct Cancer With Involvement of Both Main Hepatic Ducts Worthwhile?

HPB Surgery ◽  
1992 ◽  
Vol 5 (4) ◽  
pp. 235-249 ◽  
Author(s):  
Dietmar K. Wilker ◽  
Jakob R. Izbicki ◽  
Ralf Rohloff ◽  
Wolfram-T. Knoefel ◽  
Hans Mandelkow ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Bile Duct ◽  
Bile Duct Cancer ◽  
Tumor Resection ◽  
Residual Tumor ◽  
Survival Times ◽  
Bilioenteric Anastomosis ◽  
Duct Cancer ◽  
Proximal Bile Duct

The only curative treatment for proximal bile duct cancer with involvement of both main hepatic ducts is liver transplantation. Most patients do not fulfill the requirements for liver transplantation. Our treatment strategy in appropriate cases is palliative tumor resection and reconstruction of the biliary passage by sutureless bilioenteric anastomosis. We have treated 12 patients, 5 in combination with intraluminal and percutaneous radiotherapy. Our results indicate that this strategy leads to effective palliation in some cases provided that only microscopic residual tumor is left in-situ. Our survival times compare favourably with survival after liver transplantation.

scholarly journals Proximal Bile Duct Cancer: High Resectability Rate and 5-Year Survival

1999 ◽  
Vol 230 (2) ◽  
pp. 266 ◽  
Author(s):  
Bernard Launois ◽  
John Terblanche ◽  
Mohamed Lakehal ◽  
Jean Marc Catheline ◽  
Eustathios Bardaxoglou ◽  
...  
Keyword(s):  
Bile Duct ◽  
Bile Duct Cancer ◽  
Resectability Rate ◽  
Duct Cancer ◽  
Proximal Bile Duct

Surgical strategy for the management of hilar bile duct cancer

1997 ◽  
Vol 84 (12) ◽  
pp. 1675-1679 ◽  
Author(s):  
Y. Parc ◽  
P. Frileux ◽  
P. Balladur ◽  
E. Delva ◽  
L. Hannoun ◽  
...  
Keyword(s):  
Bile Duct ◽  
Bile Duct Cancer ◽  
Surgical Strategy ◽  
Hilar Bile Duct Cancer ◽  
Hilar Bile Duct ◽  
Duct Cancer

A Case Report of Proximal Bile Duct Cancer in Which Intraportal Endovascular Ultrasonography was Useful to Formulate the Operative Strategy.

1994 ◽  
Vol 27 (1) ◽  
pp. 125-129
Author(s):  
Tetsuya Kaneko ◽  
Akimasa Nakao ◽  
Soichiroh Inoue ◽  
Akio Harada ◽  
Toshiaki Nonami ◽  
...  
Keyword(s):  
Case Report ◽  
Bile Duct ◽  
Bile Duct Cancer ◽  
Operative Strategy ◽  
Duct Cancer ◽  
Proximal Bile Duct

Surgical management of proximal bile duct cancer: extended right lobe resection increases resectability and radicality

2003 ◽  
Vol 388 (3) ◽  
pp. 194-200 ◽  
Author(s):  
Peter Neuhaus ◽  
Sven Jonas ◽  
Utz Settmacher ◽  
Armin Thelen ◽  
Christoph Benckert ◽  
...  
Keyword(s):  
Bile Duct ◽  
Surgical Management ◽  
Bile Duct Cancer ◽  
Right Lobe ◽  
Duct Cancer ◽  
Proximal Bile Duct

scholarly journals Proximal Bile Duct Cancer

1987 ◽  
Vol 205 (2) ◽  
pp. 111-118 ◽  
Author(s):  
EDWARD C. S. LAI ◽  
RONALD K. TOMPKINS ◽  
JOEL J. ROSLYN ◽  
LINDA L. MANN
Keyword(s):  
Bile Duct ◽  
Bile Duct Cancer ◽  
Duct Cancer ◽  
Proximal Bile Duct
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