Liposomes as drug delivery system in the treatment of infectious diseases potential applications and clinical experience

Infection ◽  
1988 ◽  
Vol 16 (3) ◽  
pp. 141-147 ◽  
Author(s):  
A. Coune
2021 ◽  
Vol 21 ◽  
Author(s):  
Madhukar Garg ◽  
Anju Goyal ◽  
Sapna Kumari

: Cubosomes are highly stable nanostructured liquid crystalline dosage delivery form derived from amphiphilic lipids and polymer-based stabilizers converting it in a form of effective biocompatible carrier for the drug delivery. The delivery form comprised of bicontinuous lipid bilayers arranged in three dimensional honeycombs like structure provided with two internal aqueous channels for incorporation of number of biologically active ingredients. In contrast liposomes they provide large surface area for incorporation of different types of ingredients. Due to the distinct advantages of biocompatibility and thermodynamic stability, cubosomes have remained the first preference as method of choice in the sustained release, controlled release and targeted release dosage forms as new drug delivery system for the better release of the drugs. As lot of advancement in the new form of dosage form has bring the novel avenues in drug delivery mechanisms so it was matter of worth to compile the latest updates on the various aspects of mentioned therapeutic delivery system including its structure, routes of applications along with the potential applications to encapsulate variety drugs to serve health related benefits.


2021 ◽  
Vol 11 (4-S) ◽  
pp. 166-170
Author(s):  
Chanchal Joy ◽  
Smitha K. Nair ◽  
K Krishna Kumar ◽  
B Dineshkumar

Niosomes are considered as novel nano-carrier in the drug delivery systems. These are much more stable than other nano-carriers like liposomes and nanoparticles. It is an example for targeted and control release of medication. The drug is entrapped into lipid core so that it prevents the drug from leaching. Here the drug will be targeted only to the desired cell/tissue and not to the non-targeted cells. By giving this formulation we can thereby reduce the dose of the drug and toxicity. This review article mainly emphasizes on the potential applications of niosomes in targeted drug delivery system. Keywords: niosomes, nanocarriers, targeted drug delivery.


2002 ◽  
Vol 8 (6) ◽  
pp. 455-465 ◽  
Author(s):  
Yoko Shoji ◽  
Jingoro Shimada ◽  
Yutaka Mizushima

2017 ◽  
Vol 9 (3) ◽  
pp. 1 ◽  
Author(s):  
Smita Bonde ◽  
Sukanya Nair

Liposomes are an efficient novel drug delivery system. They are used because of their structure which is stable and due to their ability to accommodate both lipophilic and hydrophilic drug. Various fascinating types of liposomes have been developed in recent past to further enhance their utility. Long-circulating liposomes or stealth liposomes are able to hide from the defence system of the body and circulate for a longer time in the blood. Targeted liposomes namely immuno- liposomes consists of antibodies conjugated on their surface to improve the specificity of the cell. Liposomes have been modified as per the conditions of pH and temperature, specifically designed to improve drug delivery to targeted tumor cells. Liposomes are being used in the treatment of various diseases and there are various liposomal drug formulations available today. Liposomes can be used as carriers for genetic materials such as antisense, DNA, RNA which are useful in the treatment of diseases. Liposomes are also efficient carriers of cytokines which further activate macrophages. This review provides the detailed insight of types and applications of liposomes and the potential challenges in the development of liposomal drug delivery systems.


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