scholarly journals Results of autogenous vein grafts in repair of major arterial injuries to the upper and lower extremities with reference to wall shear stress

2011 ◽  
Vol 6 (02) ◽  
pp. 99-103
Author(s):  
Li Zhao ◽  
Yao-tian Huang ◽  
Jun Li ◽  
Min Huang
Author(s):  
Michelle Consolini ◽  
Tiziano Passerini ◽  
Marina Piccinelli ◽  
Brandon Fornwalt ◽  
Nick G. Willett ◽  
...  

Abdominal aortic aneurysms (AAAs) develop in the infrarenal aorta of humans and in the suprarenal aorta of apoE−/− mice infused with angiotensin II (AngII). Oscillatory wall shear stress in the infrarenal human abdominal aorta is driven by the flow to the gastric arteries, the lumbar curvature and the capacitance of the lower extremities [1]. Two of these factors, the lumbar curvature and the capacitance of the lower extremities, are significantly different in mice than in humans. Therefore, we hypothesized that the differences in localization of AAAs between species is explained by differences in the pattern of wall shear stress via the shear-regulated modulation of inflammatory pathways involving AngII.


2011 ◽  
Vol 11 (05) ◽  
pp. 1059-1070 ◽  
Author(s):  
Q. JI ◽  
Y. Q. MEI ◽  
X. S. WANG ◽  
D. W. WUSHA

This study aimed to evaluate short-term changes of wall shear stress and circumferential stress in a self-designed double-layer vein graft in a porcine vein graft model. In this study, left and right hind femoral arteries of 40 white pigs were randomly divided into an experimental group (double-layer vein graft) and a control group (single-layer vein graft). At one hour and then at one, two and four weeks after venous bypass grafting, sets of ten animals underwent Doppler-ultrasonic and electromagnetic flowmeter examinations to calculate wall shear stress in middle sections of the vein grafts. Then, the vein grafts were excised and subjected to mechanical tests to assess the circumferential stress. As a result, the double-layer vein grafts showed an increase in wall shear stress by 43.5% compared with the control group at one hour after venous bypass grafting. With time wall shear stress gradually increased, the intimal circumferential stress gradually decreased in the two groups. Intimal circumferential stress in the experimental group was significantly lower than that in the control group at each observational time-point. Hence, the double-layer support of the vein graft may have contributed towards a rise in wall shear stress and reduction in circumferential stress in the true vein graft over the four-week period after venous bypass grafting, and thus conferring some protection to the true vein graft.


Author(s):  
Brett Freidkes ◽  
David A. Mills ◽  
Casey Keane ◽  
Lawrence S. Ukeiley ◽  
Mark Sheplak

2020 ◽  
Vol 59 (SK) ◽  
pp. SKKE16 ◽  
Author(s):  
Ryo Nagaoka ◽  
Kazuma Ishikawa ◽  
Michiya Mozumi ◽  
Magnus Cinthio ◽  
Hideyuki Hasegawa

Water ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 1587
Author(s):  
Dolat Khan ◽  
Ata ur Rahman ◽  
Gohar Ali ◽  
Poom Kumam ◽  
Attapol Kaewkhao ◽  
...  

Due to the importance of wall shear stress effect and dust fluid in daily life fluid problems. This paper aims to discover the influence of wall shear stress on dust fluids of fluctuating flow. The flow is considered between two parallel plates that are non-conducting. Due to the transformation of heat, the fluid flow is generated. We consider every dust particle having spherical uniformly disperse in the base fluid. The perturb solution is obtained by applying the Poincare-Lighthill perturbation technique (PLPT). The fluid velocity and shear stress are discussed for the different parameters like Grashof number, magnetic parameter, radiation parameter, and dusty fluid parameter. Graphical results for fluid and dust particles are plotted through Mathcad-15. The behavior of base fluid and dusty fluid is matching for different embedded parameters.


2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Fan He ◽  
Lu Hua ◽  
Tingting Guo

Abstract Background The effects of arterial wall compliance on blood flow have been revealed using fluid-structure interaction in last decades. However, microcirculation is not considered in previous researches. In fact, microcirculation plays a key role in regulating blood flow. Therefore, it is very necessary to involve microcirculation in arterial hemodynamics. Objective The main purpose of the present study is to investigate how wall compliance affects the flow characteristics and to establish the comparisons of these flow variables with rigid wall when microcirculation is considered. Methods We present numerical modeling in arterial hemodynamics incorporating fluid-structure interaction and microcirculation. A novel outlet boundary condition is employed to prescribe microcirculation in an idealised model. Results The novel finding in this work is that wall compliance under the consideration of microcirculation leads to the increase of wall shear stress in contrast to rigid wall, contrary to the traditional result that wall compliance makes wall shear stress decrease when a constant or time dependent pressure is specified at an outlet. Conclusions This work provides the valuable study of hemodynamics under physiological and realistic boundary conditions and proves that wall compliance may have a positive impact on wall shear stress based on this model. This methodology in this paper could be used in real model simulations.


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