The excitation spectra of tetrahedral complex compounds of manganese(II) bromide with hydrobromides of some derivatives of pyridine and pyperidine

1977 ◽  
Vol 27 (2) ◽  
pp. 224-232 ◽  
Author(s):  
I. Burić ◽  
K. Nikolić ◽  
A. Aleksić
Keyword(s):  
Complex Compounds ◽  
Tetrahedral Complex ◽  
Excitation Spectra ◽  
Derivatives Of

scholarly journals Synthesis, Complex Compounds and Antimicrobial Activity of Some Derivatives of Furo[3,2-C]Pyridine and Their Starting Compounds

2012 ◽  
Vol 11 (1) ◽  
pp. 73-85
Author(s):  
Martin Hrašna ◽  
Eva Ürgeová ◽  
Alžbeta Krutošíková
Keyword(s):  
Antimicrobial Activity ◽  
Boronic Acid ◽  
Erwinia Amylovora ◽  
Phosphorus Oxychloride ◽  
Coupling Reaction ◽  
Complex Compounds ◽  
Suzuki Coupling Reaction ◽  
Propenoic Acid ◽  
Unexpected Product ◽  
Derivatives Of

Synthesis, Complex Compounds and Antimicrobial Activity of Some Derivatives of Furo[3,2-C]Pyridine and Their Starting CompoundsSome [3,2-c]pyridine derivatives were synthesized. 3-(Furan-2-yl)propenoic acid (1a) was prepared from furan-2-carbaldehyde under the Perkin's conditions. Obtained acid was converted to the corresponding azide3, which in turn was cyclized to give furo[3,2-c]pyridin-4(5H)-one (4a). The reaction of pyridone4awith phosphorus oxychloride rendered the chloroderivative7a, which was treated in the condition of Suzuki coupling reaction with boronic acid to give 4-phenylfuro[3,2-c]pyridine (8e) and an unexpected product10. Some title compounds have shown moderate to good antimicrobial activity against tested bacteriaXanthomonas sp., Erwinia amylovora, and filamentous fungiPyrenophora avenae, Fusarium graminearum.

Synthesis of Complex Compounds of Methyl Derivatives of 8-Quinolineselenol with Metals and Their Cytotoxic Activity.

ChemInform ◽  
2006 ◽  
Vol 37 (35) ◽  
Author(s):  
E. Lukevics ◽  
I. Shestakova ◽  
I. Domracheva ◽  
A. Nesterova ◽  
J. Ashaks ◽  
...  
Keyword(s):  
Cytotoxic Activity ◽  
Complex Compounds ◽  
Methyl Derivatives ◽  
Derivatives Of

Effect of complex compounds of methyl derivatives of 5-hydroxyuracil with succinic acid on the antioxidant system and the morpho-functional state of the liver of old rats exposed to carbon tetrachloride

2017 ◽  
pp. 52-56 ◽  
Author(s):  
В.А. Мышкин ◽  
Д.А. Еникеев ◽  
И.Д. Габдрахманова ◽  
Д.В. Срубилин ◽  
А.Р. Гимадиева ◽  
...  
Keyword(s):  
Carbon Tetrachloride ◽  
Succinic Acid ◽  
Functional State ◽  
Antioxidant System ◽  
Free Radical Oxidation ◽  
Complex Compounds ◽  
Corrective Effect ◽  
Old Rats ◽  
Methyl Derivatives ◽  
Derivatives Of

Цель. Изучение влияния комплексных соединений - 5-гидрокси-1,3,6-триметилурацила с сукцинатом (1) и 5-гидрокси-3,6-диметилурацила с сукцинтом (2) - на процессы перекисного окисления липидов (ПОЛ), антиоксидантную систему (АОС) и морфофункциональное состояние печени старых крыс при токсикозе, вызванном тетрахлорметаном. Методы. Опыты выполнены на 50 белых беспородных крысах-самцах, массой более 400 г. Токсическое поражение печени вызывали введением 50%-ного масляного раствора тетрахлорметана (ТХМ) (2 г/кг, п/к) в течение 4 дней [6]. Одновременно вводили исследуемые препараты - соединения 1, 2 и референтный препарат силимарин (50 мг/кг, в/бр) 3 раза в сутки в течение первых 4 дней и в течение последующих 3 дней 1 раз в сутки. Через 7 дней от начала введений исследовали сыворотку крови и печень. Результаты. Комплексные соединения 1 и 2 ограничивали некрозогенное действие ТХМ частично сохраняли функционально-метаболическую активность за счет благоприятного влияния на ферменты (АсАТ, ЩФ), содержание общего билирубина и холестерина в крови, а также за счет частичной нормализации нарушенного равновесия ПОЛ/АОС. Комплексное соединение 5-гидрокси-1,3,6-триметилурацила с сукцинатом более эффективно, чем соединение 2, уменьшало интенсивность и распространенность дистрофических и некротических процессов у старых крыс и существенно ограничивало выраженность гепатотоксического действия ТХМ. Заключение. Защитное действие 5-гидрокси-1,3,6-триметилурацила с сукцинатом было связано с корригирующим влиянием на глутатионовую и ферментативную системы антиоксидантной защиты. The influence of two new complex compounds of methyl derivatives of 5-hydroxyuracil with succinic acid on the antioxidant system and morpho-functional state of the liver of old rats exposed to carbon tetrachloride has been studied experimentally. The aim was to study the influence of complex compounds - 5-hydroxy -1,3,6 - trimethyluracil succinate (1) and 5-hydroxy-3,6-dimethyluracil succinate (2) - on the processes of free radical oxidation, antioxidant system regulating these processes and morpho-functional state of the liver of old rats exposed to carbon tetrachloride. Results. Complex Compounds 1 and 2 used prophylactically in old rats ( 50 mg/kg three times/day х 4 intraperitoneally, then 50 mg/kg once/ per day x 3 intraperitoneally) have been shown to limit necrosogenic effects of TCR ( 2 g/kg/day><4 subcutaneously), to preserve partially functional - metabolic activity due to favorable effects on enzymes (AST, alkaline phosphatase), total blood bilirubin and cholesterol and also due to partial normalization of POL/AOS imbalance. According to most indicators, Compound 1 turns out to be more effective and comparable to the effect of the silymin hepatoprotector. Conclusion. The cCompound 1 reduced the intensity and prevalence of dystrophic and necrotic processes of cellular reactions of the liver tissues in old rats and limited significantly the severity of TCR hepatotoxicity due to a corrective effect on glutathione and enzymatic antioxidant defense system.

Antimicrobial activity of derivatives of benz-2,1,3-thia-and selenadiazoles and their complex compounds with copper [2+] chloride

1985 ◽  
Vol 19 (11) ◽  
pp. 788-792
Author(s):  
�. A. Bezzubets ◽  
E. K. D'yachenko ◽  
N. G. Tikhomirova ◽  
N. A. Ostapkevich ◽  
E. T. Mordvinova ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Complex Compounds ◽  
Derivatives Of

Metallic Complexes with the Aliphatic Poly-Amines

1926 ◽  
Vol 23 (2) ◽  
pp. 183-186
Author(s):  
F. G. Mann ◽  
William J. Pope
Keyword(s):  
General Chemistry ◽  
Complex Compounds ◽  
Early Years ◽  
Ethylene Diamine ◽  
Salt Formation ◽  
Aliphatic Diamine ◽  
Metallic Salts ◽  
Dark Green ◽  
Derivatives Of ◽  
Coloured Compound

The existence of complex compounds of metallic salts with ammonia was recognised in the early years of last century. Platinum in particular readily unites with ammonia, and the early chemists, when studying the general chemistry of ammonium platino-and platini-chlorides, soon discovered highly crystalline ammonia derivatives of platinum which contained an unusually high proportion of the metal. In the formulation of such compounds difficulties at once arose. Thus Peyrone in 1844 knew three distinct compounds of the composition PtCl2N2H6, a pale lemoncoloured compound known as the second chloride of Reiset, an orange-coloured compound discovered by Peyrone himself, and finally a dark green insoluble substance known as Magnus' green salt, discovered by the latter in 1828. The existence of these three compounds, now known as trans and cis dichloro-diaminoplatinum [Pt(NH3)2Cl2], and as tetramino-platinous platinochloride [Pt(NH3)4]PtCl4 respectively, could not be satisfactorily explained on current theories of salt formation. Similar compounds in which aliphatic and cyclic mono-amines replaced the ammonia groups were discovered later, but it was not until 1889 that Jörgensen introduced the use of the simplest stable aliphatic diamine, viz. ethylene diamine.

Synthesis of complex compounds of methyl derivatives of 8-quinolineselenol with metals and their cytotoxic activity

2006 ◽  
Vol 42 (1) ◽  
pp. 53-59 ◽  
Author(s):  
E. Lukevics ◽  
I. Shestakova ◽  
I. Domracheva ◽  
A. Nesterova ◽  
J. Ashaks ◽  
...  
Keyword(s):  
Cytotoxic Activity ◽  
Complex Compounds ◽  
Methyl Derivatives ◽  
Derivatives Of

Crystal chemical data on inner complex compounds of N-substituted derivatives of salicylalimine

1971 ◽  
Vol 11 (5) ◽  
pp. 819-823 ◽  
Author(s):  
L. M. Shkol'nikova ◽  
E. M. Yumal' ◽  
E. A. Shugam ◽  
V. A. Voblikova
Keyword(s):  
Complex Compounds ◽  
Chemical Data ◽  
Crystal Chemical ◽  
Crystal Chemical Data ◽  
Derivatives Of
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