Utility of inpatient 24-hour intraesophageal pH monitoring in diagnosis of gastroesophageal reflux

1988 ◽  
Vol 33 (9) ◽  
pp. 1134-1140 ◽  
Author(s):  
Amadeo Pujol ◽  
Lu�s Grande ◽  
Emilio Ros ◽  
Crist�bal Pera
Keyword(s):  
Gastroesophageal Reflux ◽  
Ph Monitoring ◽  
Intraesophageal Ph Monitoring

Intraesophageal pH Monitoring after Breakfast + Lunch in Gastroesophageal Reflux

1988 ◽  
Vol 10 (4) ◽  
pp. 373-376 ◽  
Author(s):  
L. Grande ◽  
A. Pujol ◽  
E. Ros ◽  
J. C. Garcia-Valdecasas ◽  
J. Fuster ◽  
...  
Keyword(s):  
Gastroesophageal Reflux ◽  
Ph Monitoring ◽  
Intraesophageal Ph Monitoring

Gastroesophageal Reflux Disease and Idiopathic Lung Fibrosis. From Heartburn to Lung Transplant, and Beyond

2021 ◽  
pp. 000313482199868
Author(s):  
Fernando A. M. Herbella ◽  
Marco G. Patti
Keyword(s):  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Reflux Disease ◽  
Lung Fibrosis ◽  
Bronchiolitis Obliterans ◽  
Lung Transplant ◽  
Ph Monitoring ◽  
Objective Evaluation ◽  
Bronchiolitis Obliterans Syndrome ◽  
Laparoscopic Operation

Idiopathic pulmonary fibrosis (IPF) and gastroesophageal reflux disease (GERD) are undoubtedly related. Even though it is not clear yet which one is the primary disease, they certainly interact increasing each other’s severity. Symptoms are unreliable to diagnose GERD in patients with IPF, and objective evaluation with pH monitoring and/or bronchoalveolar lavage analysis is mandatory. Pharmacological treatment with proton pump inhibitors (PPIs) may bring control of IPF in few patients, but PPIs do not control reflux but just change the pH of the gastric refluxate. Surgical therapy based on a fundoplication is safe and effective as it controls any type of reflux, independently from the pH of the gastric refluxate. In patients waiting for lung transplantation (if they can tolerate a laparoscopic operation under general anesthesia), a fundoplication before the operation might block the progression of IPF, while after transplantation it might prevent rejection by preventing the bronchiolitis obliterans syndrome.

Sign in / Sign up

Export Citation Format

Share Document