Assignment of human gene encoding thymidylate synthase to chromosome 18 using interspecific cell hybrids between thymidylate synthase-Negative mouse mutant cells and human diploid fibroblasts

1985 ◽  
Vol 11 (3) ◽  
pp. 277-283 ◽  
Author(s):  
Tada-aki Hori ◽  
Dai Ayusawa ◽  
Kimiko Shimizu ◽  
Hideki Koyama ◽  
Takeshi Seno
Keyword(s):  
Thymidylate Synthase ◽  
Human Gene ◽  
Mouse Mutant ◽  
Chromosome 18 ◽  
Gene Encoding ◽  
Diploid Fibroblasts ◽  
Human Diploid Fibroblasts ◽  
Cell Hybrids ◽  
Interspecific Cell Hybrids ◽  
Mutant Cells

scholarly journals Multiple human beta interferon genes.

1982 ◽  
Vol 156 (3) ◽  
pp. 744-755 ◽  
Author(s):  
A D Sagar ◽  
P B Sehgal ◽  
D L Slate ◽  
F H Ruddle
Keyword(s):  
Somatic Cell ◽  
Human Chromosomes ◽  
Somatic Cell Hybrids ◽  
Diploid Fibroblasts ◽  
Mrna Species ◽  
Human Diploid Fibroblasts ◽  
Beta Interferon ◽  
Cell Hybrids ◽  
Marked Cell ◽  
Mouse Somatic Cell

Analysis of human beta interferon (IFN) mRNA preparations obtained from poly(I) . poly (C)-induced human diploid fibroblasts (FS-4) and from several similarly induced human-mouse somatic cell hybrids by electrophoresis through agarose-CH3HgOH tube gels led to the detection of at least five translationally active human IFN-beta mRNA species. The results obtained are consistent with the existence of IFN-beta genes on different human chromosomes. Marked cell-dependent variability in the expression of these IFN mRNA species was observed.

Cell-cycle-directed regulation of thymidylate synthase messenger RNA in human diploid fibroblasts stimulated to proliferate

1986 ◽  
Vol 190 (4) ◽  
pp. 559-567 ◽  
Author(s):  
Dai Ayusawa ◽  
Kimiko Shimizu ◽  
Hideki Koyama ◽  
Sumiko Kaneda ◽  
Keiichi Takeishi ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Thymidylate Synthase ◽  
Messenger Rna ◽  
Diploid Fibroblasts ◽  
Human Diploid Fibroblasts
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