Effect of combined administration of a synthetic low-toxicity lipid A derivative, DT-5461a, and indomethacin in various experimental tumor models of colon 26 carcinoma in mice

Takeshi Jimbo; Toshihiko Akimoto; Akiko Tohgo

doi:10.1007/bf01517230

Effect of combined administration of a synthetic low-toxicity lipid A derivative, DT-5461a, and indomethacin in various experimental tumor models of colon 26 carcinoma in mice

Cancer Immunology Immunotherapy ◽

10.1007/bf01517230 ◽

1995 ◽

Vol 40 (1) ◽

pp. 10-16 ◽

Cited By ~ 7

Author(s):

Takeshi Jimbo ◽

Toshihiko Akimoto ◽

Akiko Tohgo

Keyword(s):

Lipid A ◽

Tumor Models ◽

Experimental Tumor ◽

Colon 26 ◽

Combined Administration ◽

Low Toxicity

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Effect of combined administration of a synthetic low-toxicity lipid A derivative, DT-5461a, and indomethacin in various experimental tumor models of colon 26 carcinoma in mice

Cancer Immunology Immunotherapy ◽

10.1007/s002620050138 ◽

1995 ◽

Vol 40 (1) ◽

pp. 10-16 ◽

Cited By ~ 1

Author(s):

T. Jimbo ◽

Toshihiko Akimoto ◽

Akiko Tohgo

Keyword(s):

Lipid A ◽

Tumor Models ◽

Experimental Tumor ◽

Colon 26 ◽

Combined Administration ◽

Low Toxicity

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Induction of intratumoral tumor necrosis factor by a synthetic lipid A analog, ONO-4007, with less tolerance in repeated administration and its implication in potent antitumor effects with low toxicity

Cancer Immunology Immunotherapy ◽

10.1007/s00262-001-0241-7 ◽

2002 ◽

Vol 50 (12) ◽

pp. 653-662 ◽

Cited By ~ 8

Author(s):

Motonobu Satoh, Kazusa Tsurumaki, Hideaki Ka

Keyword(s):

Tumor Necrosis Factor ◽

Tumor Necrosis ◽

Lipid A ◽

Repeated Administration ◽

Antitumor Effects ◽

Low Toxicity ◽

Necrosis Factor

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Induction of an endogenous tumor necrosis factor in mice by murine recombinant interferon-? combined with a lipid A subunit analog (GLA-60) of low toxicity

Cancer Immunology Immunotherapy ◽

10.1007/bf00199284 ◽

1989 ◽

Vol 29 (2) ◽

Cited By ~ 14

Author(s):

Ikuo Saiki ◽

Hiroaki Maeda ◽

Takuma Sakurai ◽

Jun Murata ◽

Joji Iida ◽

...

Keyword(s):

Tumor Necrosis Factor ◽

Tumor Necrosis ◽

Lipid A ◽

Recombinant Interferon ◽

A Subunit ◽

Low Toxicity ◽

Necrosis Factor

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The combination of nemorubicin with cisplatin and mitomycin C is synergistic in experimental tumor models

European Journal of Cancer ◽

10.1016/s0959-8049(02)80695-5 ◽

2002 ◽

Vol 38 ◽

pp. S20

Keyword(s):

Mitomycin C ◽

Tumor Models ◽

Experimental Tumor

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Significant antitumor effect of a synthetic lipid A analogue, DT-5461, on murine syngeneic tumor models

Cancer Immunology Immunotherapy ◽

10.1007/bf01741143 ◽

1992 ◽

Vol 35 (5) ◽

pp. 307-314 ◽

Cited By ~ 15

Author(s):

Eiji Kumazawa ◽

Akiko Tohgo ◽

Tsunehiko Soga ◽

Tsuneo Kusama ◽

Yasuaki Osada

Keyword(s):

Antitumor Effect ◽

Lipid A ◽

Tumor Models ◽

Syngeneic Tumor

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Antitumor effect of DT-5461a, a synthetic low-toxicity lipid a analog, involves endogenous tumor necrosis factor induction subsequent to macrophage activation

International Journal of Immunopharmacology ◽

10.1016/0192-0561(94)90043-4 ◽

1994 ◽

Vol 16 (11) ◽

pp. 887-893 ◽

Cited By ~ 10

Author(s):

Toshihiko Akimoto ◽

Eiji Kumazawa ◽

Takeshi Jimbo ◽

Noriko Joto ◽

Akiko Tohgo

Keyword(s):

Tumor Necrosis Factor ◽

Tumor Necrosis ◽

Macrophage Activation ◽

Antitumor Effect ◽

Lipid A ◽

Low Toxicity ◽

Tumor Necrosis Factor Induction ◽

Necrosis Factor

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Immunomodulatory effects of soluble CD5 on experimental tumor models

Oncotarget ◽

10.18632/oncotarget.22564 ◽

2017 ◽

Vol 8 (64) ◽

pp. 108156-108169 ◽

Cited By ~ 6

Author(s):

Inês T. Simões ◽

Fernando Aranda ◽

Esther Carreras ◽

Maria Velasco-de Andrés ◽

Sergi Casadó-Llombart ◽

...

Keyword(s):

Immunomodulatory Effects ◽

Tumor Models ◽

Experimental Tumor

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Abstract B46: Small-molecule inhibitors of ecto-nucleotidase CD73 promote activation of human CD8+ T cells and have profound effects on tumor growth and immune parameters in experimental tumor models

10.1158/2326-6074.tumimm16-b46 ◽

2017 ◽

Author(s):

Joanne BL Tan ◽

Ada Chen ◽

Manmohan Leleti ◽

Annette Becker ◽

Erick Lindsey ◽

...

Keyword(s):

T Cells ◽

Tumor Growth ◽

Small Molecule ◽

Cd8 T Cells ◽

Small Molecule Inhibitors ◽

Tumor Models ◽

Experimental Tumor ◽

Immune Parameters

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Low toxicity signaling by monophosphoryl Lipid A

Cytokine ◽

10.1016/j.cyto.2009.07.545 ◽

2009 ◽

Vol 48 (1-2) ◽

pp. 129

Author(s):

Thomas C. Mitchell ◽

Caglar Cekic ◽

Carolyn R. Casella ◽

Chelsea A. Eaves

Keyword(s):

Lipid A ◽

Monophosphoryl Lipid A ◽

Monophosphoryl Lipid ◽

Low Toxicity

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Hypoxia and angiogenesis in experimental tumor models: Therapeutic implications

Experientia Supplementum - Regulation of Angiogenesis ◽

10.1007/978-3-0348-9006-9_14 ◽

1997 ◽

pp. 335-360 ◽

Cited By ~ 4

Author(s):

S. Rockwell ◽

J. P. S. Knisely

Keyword(s):

Tumor Models ◽

Experimental Tumor ◽

Therapeutic Implications

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