Different profiles for the institutional ethics committee in the Netherlands

HEC Forum ◽  
1994 ◽  
Vol 6 (3) ◽  
pp. 139-156 ◽  
Author(s):  
Herman H. van der Kloot Meijburg
Keyword(s):  
The Netherlands ◽  
Ethics Committee ◽  
Institutional Ethics

Necrotizing Fasciitis Occurred in the Lymphedematous leg

2021 ◽  
pp. 153473462110230
Author(s):  
Hisako Hara ◽  
Makoto Mihara ◽  
Takeshi Todokoro
Keyword(s):  
Case Report ◽  
Necrotizing Fasciitis ◽  
Lower Limb ◽  
Gynecologic Cancer ◽  
Vital Signs ◽  
Ethics Committee ◽  
Secondary Lymphedema ◽  
Delayed Treatment ◽  
Institutional Ethics ◽  
Life Threatening

Lymphedema is a chronic edema that sometimes occurs after treatment of gynecologic cancer, and cellulitis often occurs concomitantly with lymphedema. On the other hand, necrotizing fasciitis (NF) is a relatively rare, but life-threatening disease. The symptoms in cellulitis and NF are very similar. In this case report, we describe a case in which the diagnosis of NF in a lymphedematous limb was difficult. A 70-year-old woman had secondary lymphedema in bilateral legs and consulted our department. On the first day of lymphedema therapy, the patient complained of vomiting, diarrhea, and fever (37.7 °C) without local fever in the legs. She was diagnosed with acute gastroenteritis. On the next day, swelling and pain in her left leg occurred and her blood pressure was 59/44 mmHg. She was diagnosed with cellulitis accompanied by lower limb lymphedema and septic shock. On the second day, blisters appeared on the left leg, and computed tomography showed NF. We performed debridement under general anesthesia and her vital signs improved postoperatively. Streptococcus agalactiae (B) was detected in blood culture, and we administered bixillin and clindamycin. Postoperatively, necrosis in the skin and fat around the left ankle gradually spread, and it took 5 months to complete epithelialization. The diagnosis was more difficult than usual NF because patients with lymphedema often experience cellulitis. Clinicians should always think of NF to avoid mortality due to delayed treatment. This case report was approved by the institutional ethics committee.

scholarly journals Institutional Ethics Committee Regulations and Current Updates in India

2017 ◽  
Vol 18 (8) ◽  
pp. 738-741
Author(s):  
Amit V Mahuli ◽  
Simpy A Mahuli
Keyword(s):  
Ethics Committees ◽  
Ethics Committee ◽  
Trial Registry ◽  
Clinical Trial Registry ◽  
Multiple Factors ◽  
Research Guidelines ◽  
Institutional Ethics ◽  
Controller General ◽  
Human Participants ◽  
Indian Scenario

ABSTRACT Aim The aim of the review is to provide current updates on regulations for ethics committees and researchers in India. Background Ethical dilemmas in research since time immemorial have been a major concern for researchers worldwide. The question “what makes clinical research ethical” is significant and difficult to answer as multiple factors are involved. Review results The research involving human participants in clinical trials should follow the required rules, regulations, and guidelines in one's own country. It is a dynamic process, and updates have to be learned by researcher and committee members. The review highlights the ethical regulation from the Drug Controller General of India, Clinical Trial Registry of India, and Indian Council of Medical Research guidelines. Conclusion In this article, the updates on Indian scenario of the Ethical Committee and guidelines are compiled. Clinical significance The review comes handy for clinical researchers and ethics committee members in academic institutions to check on the current updates and keep abreast with the knowledge on regulations of ethics in India. How to cite this article Mahuli AV, Mahuli SA, Patil S, Bhandi S. Institutional Ethics Committee Regulations and Current Updates in India. J Contemp Dent Pract 2017;18(8):738-741.

scholarly journals A clinical study of effects of pregnancy on diseases like painful crisis, seizure disorders, hepatopathy, acute anemia and its outcome

2019 ◽  
Vol 8 (5) ◽  
pp. 1860
Author(s):  
V. Sitalakshmi ◽  
Narmada . ◽  
Kavitha .
Keyword(s):  
Blood Cells ◽  
Andhra Pradesh ◽  
Ethics Committee ◽  
Lower Amount ◽  
Careful Monitoring ◽  
Medical College ◽  
Seizure Disorders ◽  
Institutional Ethics ◽  
Healthy Pregnancy ◽  
In Pregnancy

Background: The ability of the blood cells to carry oxygen is especially important in pregnancy. Anemia may result in lower amount of oxygen going to the fetus and slowed fetal growth. Because it affects so many organs and body systems, women with the disease are more likely to have complications in pregnancy. The main objective was to study the effects of pregnancy on disease and its outcomes.Methods: It is a hospital based prospective study. The study was conducted at Narayana Medical College Nellore, Andhra Pradesh. The patients admitted in Obstetrics and Gynecology Department were included in the study. The study included total of 45 patients. Detailed history included age, socioeconomic status, address, education and occupation of the patient’s Permission from Institutional Ethics Committee was obtained.Results: Maximum patients were gravida 2-3, and minimum were gravida 4 or more. Maximum numbers of patients were in group 20-25. The patients with preterm birth that is delivery before 37 weeks of pregnancy were 15. Low birth weights were 20 and of still birth and new born death was 4.Conclusions: The present study was carried out in 45 cases and appropriate prenatal care and careful monitoring throughout pregnancy, can have healthy pregnancy with significant improvement in pregnancy outcome.

Impact of recent regulatory notifications on an institutional ethics committee

2016 ◽  
Author(s):  
Shruti S Bhide ◽  
Sharmila V Jalgaonkar ◽  
Janhavi V Katkar ◽  
Yashashri C Shetty ◽  
Raakhi K Tripathi ◽  
...  
Keyword(s):  
Ethics Committee ◽  
Institutional Ethics

scholarly journals Analysis of medication errors in medicine ward of medical college teaching hospital, Mandya

2019 ◽  
Vol 8 (12) ◽  
pp. 2741
Author(s):  
Supriya K. H. ◽  
Shashikumar N. S. ◽  
Prakash G. M. ◽  
Rajeshwari N.
Keyword(s):  
Medication Error ◽  
Medication Errors ◽  
Healthcare Professionals ◽  
Medication Use ◽  
College Teaching ◽  
Ethics Committee ◽  
Medical College ◽  
Parenteral Route ◽  
Institutional Ethics ◽  
Hospitalised Patients

Background: Medication errors are one of the most common types of medical error that is seen in hospitalised patients. Since medication error is one of the growing concerns of healthcare issue and have implications on patient safety, the purpose of this study was to identify medication error and in turn would help to create awareness among healthcare professionals and provide safety to the patients.Methods: Study was initiated after obtaining approval from the Institutional Ethics Committee. The study was done for a period of 1 year between June 2016 and May 2017. Clinical data and data regarding the medication that was prescribed, transcribed, dispensed, administered was collected and was analysed for various types of medication errors during the different stages of medication use process.Results: A total of 351 subjects were recruited in the study for assessing medication error. About 2,283 drugs were prescribed among 351 patients. Maximum number of drugs was administered through parenteral route (50.3%). Medication error was most common during the prescribing stage (51.4%) followed by transcribing stage (39.1%), administration stage (6.9%), and dispensing stage (2.6%). On an average 6 drugs were prescribed per patient. Total of about 5411 errors have occurred out of which 98.8% of errors were preventable, 1.2% of errors were non-preventable. Cardiovascular system (21.9%) and endocrine and renal system (21.9%) was commonly affected due to the medication errors.Conclusions: Medication errors are one of the commonest problems of the healthcare system should be identified and documented and their causes should be studied in order to develop systems that minimize the recurrence.

scholarly journals IMPACT OF ACNE VULGARIS ON A PERSON’S QUALITY OF LIFE AND IT’S CORRELATION WITH THE CLINICAL SEVERITY PRE AND POST-DRUG THERAPY

2022 ◽  
pp. 13-16
Author(s):  
SWOPNA PHUKAN ◽  
SAHELI DAS
Keyword(s):  
Quality Of Life ◽  
Drug Therapy ◽  
Observational Study ◽  
Acne Vulgaris ◽  
Ethics Committee ◽  
Clinical Severity ◽  
Grading System ◽  
Institutional Ethics

Objective: The aim of the study is to assess the therapeutic efficacy of drugs used in acne vulgaris by measuring the severity of acne using the Global Acne Grading System score (GAGS) and Cardiff Acne Disability Index (CADI) questionnaire score pre and post-drug therapy. Methods: The present study was conducted in the Department of Dermatology after getting approval from the Institutional Ethics Committee (No MC/190/2007/Pt1/MAR-2019/PG/123) dated 10/04/2019. It was an observational study for a period of 1 y. 172 patients were enrolled in the study. Patients were divided into 4 grades depending on their clinical manifestation. The severity of acne vulgaris and the quality of life were measured using the GAGS scale and the CADI questionnaire, respectively at the first visit and at the follow-up visit in all the grades of acne vulgaris. A correlation was done between the GAGS and the CADI score at the follow-up visit in all grades of acne. Results: It was observed that the GAGS score and the CADI score was significantly improved at the F/U visit (p<0.05) as compared to baseline in all the 4 grades of acne. A correlation between GAGS score and QoL using CADI scale was done using Pearson Parametric Correlation Test. In none of the groups, the correlation was significant (p>0.05). Conclusion: We can conclude from our study that following treatment with drugs, the clinical severity of acne decreased and there was also a significant improvement in the quality of life of patients.

scholarly journals ROLE OF GINKGO BILOBA IN TINNITUS BASED ON TINNITUS HANDICAP INVENTORY

2021 ◽  
Vol Volume 9 (upjohns/volume9/Issue2) ◽  
pp. 32-36
Author(s):  
Monica Manhas
Keyword(s):  
Informed Consent ◽  
Ginkgo Biloba ◽  
Ethics Committee ◽  
P Value ◽  
Inclusion Criteria ◽  
Tinnitus Handicap Inventory ◽  
Institutional Ethics ◽  
The Mean ◽  
Pre Treatment

ABSTRACT AIMS AND OBJECTIVES To evaluate whether there is role of Ginkgo biloba in treatment of tinnitus or not, using Tinnitus Handicap Inventory MATERIAL METHODS: The present prospective study, after approval by Institutional Ethics Committee, was conducted in Department of ENT, GMC Jammu from January 2019 to January 2020 on 90 patients with primary complaint of tinnitus. Inclusion criteria- Age: 20 years or above, Duration of tinnitus > 3 months. Informed consent was taken and all patients were asked to complete the THI-Tinnitus Handicap Inventory. All patients were given 50mg of Ginkgo biloba standardized extract LI 1370 (containing 25% flavonoids, 3% ginkgolides and 5% bilobalides). Patients were advised to take three tablets daily for 12 weeks. RESULTS The mean pre-treatment THI score was 43.6 and mean post-treatment THI score (at 12 weeks) was 39.4; the mean change in THI score was 4.2, the result being statistically insignificant (p-value= 0.43). Out of 90 patients, 51 reported unchanged severity of tinnitus, 27 patients reported improvement in severity of tinnitus and 12 patients reported worsening of condition. CONCLUSION According to our study, Ginkgo biloba has no significant therapeutic role in tinnitus. However, the aetiology of tinnitus is multifactorial and Ginkgo biloba could benefit patients with ischemic aetiology. KEYWORDS Ginkgo, biloba, handicap, inventory, tinnitus

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