Alterations of local cerebral blood flow, phorbol 12,13-dibutyrate binding activity, and histological damage during acute focal ischaemia in rat brain

1996 ◽  
Vol 138 (9) ◽  
pp. 1118-1125
Author(s):  
N. Inoue ◽  
Y. L. Yamamoto ◽  
T. Nagao ◽  
S. Goto ◽  
S. Nagahiro ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Rat Brain ◽  
Binding Activity ◽  
Local Cerebral Blood Flow ◽  
Histological Damage ◽  
Focal Ischaemia

Local cerebral blood flow in the rat brain during hypercapnia and hypoxia

1983 ◽  
Vol 118 (4) ◽  
pp. 439-440 ◽  
Author(s):  
MAJ-LIS SMITH ◽  
ERIK KÅGSTRÖM ◽  
BO K. SIESJÖ
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Rat Brain ◽  
Local Cerebral Blood Flow

scholarly journals Influence of γ-Hydroxybutyrate on the Relationship between Local Cerebral Glucose Utilization and Local Cerebral Blood Flow in the Rat Brain

1985 ◽  
Vol 5 (1) ◽  
pp. 58-64 ◽  
Author(s):  
W. Kuschinsky ◽  
S. Suda ◽  
L. Sokoloff
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Rat Brain ◽  
Glucose Utilization ◽  
Local Cerebral Blood Flow ◽  
Local Cerebral Glucose Utilization ◽  
Cerebral Glucose Utilization ◽  
Minor Degree ◽  
A Minor ◽  
The Relationship

The relationship between local cerebral glucose utilization (LCGU) and local CBF (LCBF) was examined during the action of γ-hydroxybutyrate (GHB) (900 mg/kg i.v.) in conscious rats. GHB induced discrepant effects on blood flow and metabolism. LCGU was markedly depressed in all structures examined, whereas LCBF was differently affected in that no related changes were observed. Global glucose utilization was markedly depressed (- 51%), whereas global blood flow was not significantly altered. The marked dissociation between the changes in global glucose utilization and global blood flow induced by GHB is reflected only to a minor degree in the local values inasmuch as the correlation between LCGU and LCBF was only slightly weakened and its heterogeneity was increased.

scholarly journals The Velocities of Red Cell and Plasma Flows through Parenchymal Microvessels of Rat Brain are Decreased by Pentobarbital

1993 ◽  
Vol 13 (3) ◽  
pp. 487-497 ◽  
Author(s):  
Ling Wei ◽  
Tadahiro Otsuka ◽  
Virgil Acuff ◽  
Daniel Bereczki ◽  
Karen Pettigrew ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Rat Brain ◽  
High Dose ◽  
Local Cerebral Blood Flow ◽  
Brain Areas ◽  
Transit Times ◽  
Flow Through ◽  
Distribution Spaces ◽  
Local Metabolism

Local cerebral blood flow is lowered in many brain areas of the rat by high-dose pentobarbital (50 mg/kg). In the present study, the mechanism of this flow change was examined by measuring the distribution of radiolabeled red blood cells (RBCs) and albumin (RISA) in small parenchymal microvessels and calculating the microvascular distribution spaces and mean transit times of RBCs, RISA, and blood. In most brain areas, pentobarbital slightly decreased the RISA space, modestly increased the RBC space, and did not alter the blood space. The mean transit times of RBCs, RISA, and blood through the perfused microvessels were considerably greater in treated rats than in controls. These findings indicate that the mechanism by which high-dose pentobarbital diminishes local cerebral blood flow in rat brain is, in the main, a lowered linear velocity of plasma and RBC flow through small parenchymal microvessels and not decreased percentage of perfused capillaries (capillary retirement). This response is probably driven mainly by lowered local metabolism and may well entail a slight increase in the number of small microvessels that are perfused by RBCs.

scholarly journals Local Cerebral Blood Flow during Biofeedback Training

2018 ◽  
Vol 08 (03) ◽  
Author(s):  
Yasuyuki Matsuura ◽  
Toru Tanimura ◽  
Daisuke Iida ◽  
Hiroki Takada
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Biofeedback Training ◽  
Local Cerebral Blood Flow
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