Huntington disease: A case study describing the complexities and nuances of predictive testing of monozygotic twins

1995 ◽  
Vol 4 (2) ◽  
pp. 125-137 ◽  
Author(s):  
Audrey Heimler ◽  
Andrea Zanko
Keyword(s):  
Huntington Disease ◽  
Monozygotic Twins ◽  
Predictive Testing

scholarly journals Genetic or Psychogenic? A Case Study of “Folie à Quatre” Including Twins

2015 ◽  
Vol 2015 ◽  
pp. 1-3 ◽  
Author(s):  
Tohru Ohnuma ◽  
Heii Arai
Keyword(s):  
Environmental Factors ◽  
Social Isolation ◽  
Schizophrenia Patient ◽  
Monozygotic Twins ◽  
The Other ◽  
Positive Symptoms ◽  
Short Period ◽  
The Common ◽  
Shared Psychotic Disorder

Shared psychotic disorder, characterized by shared delusion among two or more subjects (termed “Folie à deux,” “trois,” etc.), is often associated with strong religious beliefs or social isolation, factors creating strong psychological sympathy. Recently, we treated a rare familial case of “Folie à quatre” in central Tokyo without such influences. The proband was a schizophrenia patient and younger brother within monozygotic twins. Positive symptoms were “transmitted” to remaining family members, his elder brother, mother, and father father, in a relatively short period of three months. Although the pathophysiology of these positive symptoms (delusions and hallucinations) remains unclear, the transmission pattern suggests the primacy of social and environmental factors (and/or their interaction), while genetics appeared less influential in this “Folie à famille.” Although undiagnosed psychoses in the whole family cannot be excluded, they did not share the other negative schizophrenia symptoms of the proband. A strong familial connection appeared to be the most important factor for the common delusion and hallucination.

scholarly journals Case Study for the Classroom: a Child with Huntington Disease

2021 ◽  
Vol 35 (S1) ◽  
Author(s):  
Laura Lorentzen ◽  
Kristie Reilly ◽  
Connor Baucom ◽  
Elizabeth Manheim
Keyword(s):  
Huntington Disease

Reactions to predictive testing in Huntington disease: Case reports of coping with a new genetic status

1997 ◽  
Vol 73 (3) ◽  
pp. 356-365 ◽  
Author(s):  
Tarja-Brita Robins Wahlin ◽  
Anders Lundin ◽  
Lars Bäckman ◽  
Elisabeth Almqvist ◽  
Aina Haegermark ◽  
...  
Keyword(s):  
Huntington Disease ◽  
Case Reports ◽  
Predictive Testing ◽  
Disease Case ◽  
Genetic Status

scholarly journals Predictive testing for Huntington disease.

1992 ◽  
Vol 18 (1) ◽  
pp. 47-48
Author(s):  
M Huggins ◽  
M R Hayden
Keyword(s):  
Huntington Disease ◽  
Predictive Testing

scholarly journals Different phenotypic expression in monozygotic twins with Huntington disease

2003 ◽  
Vol 124A (1) ◽  
pp. 89-91 ◽  
Author(s):  
M.H. Anca ◽  
E. Gazit ◽  
R. Loewenthal ◽  
O. Ostrovsky ◽  
M. Frydman ◽  
...  
Keyword(s):  
Huntington Disease ◽  
Phenotypic Expression ◽  
Monozygotic Twins

Selective loss of oxytocin and vasopressin in the hypothalamus in early Huntington disease: a case study

2015 ◽  
Vol 41 (6) ◽  
pp. 843-848 ◽  
Author(s):  
Sanaz Gabery ◽  
Glenda Halliday ◽  
Deniz Kirik ◽  
Elisabet Englund ◽  
Åsa Petersén
Keyword(s):  
Huntington Disease ◽  
Selective Loss

Motor Development of Autistic Monozygotic Twins: A Case Study

1977 ◽  
Vol 45 (1) ◽  
pp. 179-186 ◽  
Author(s):  
Dolores Geddes
Keyword(s):  
Motor Skills ◽  
Motor Development ◽  
Spatial Orientation ◽  
Monozygotic Twins ◽  
Superior Performance ◽  
Language Communication ◽  
Walking Balance ◽  
Balance Board

A pair of autistic monozygotic twins were assessed on relevant portions of the Geddes Psychomotor Inventory. Over-all motor development of the 3-yr., 6-mo. old twins was similar and considered a partial consequence of the same genotype and comparable environmental experiences from birth. The twins exhibited poor or unsuccessful performance on tasks requiring abilities in language, communication, and appropriate relationships to objects; superior performance on specific fine manual motor skills, walking balance board, and climbing; at-age performance on tasks which were considered measures of patterned gross movement, balance, postural maintenance, and spatial orientation; and few typical autistic motor characteristics.

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