CO2 reactivity of cerebral vasospasm after aneurysmal subarachnoid haemorrhage

1989 ◽  
Vol 98 (3-4) ◽  
pp. 167-175 ◽  
Author(s):  
W. Hassler ◽  
F. Chioffi
Keyword(s):  
Subarachnoid Haemorrhage ◽  
Cerebral Vasospasm ◽  
Aneurysmal Subarachnoid Haemorrhage ◽  
Co2 Reactivity

scholarly journals Literature Review of Aneurysmal Subarachnoid Hemorrhage from Incidence to Treatment Options

2020 ◽  
Vol 18 (1) ◽  
pp. 70-78
Author(s):  
Ieva Buce-Satoba ◽  
Daina Rozkalne ◽  
Jevgenijs Stepanovs ◽  
Biruta Mamaja ◽  
Gaida Krumina ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cerebral Ischemia ◽  
Literature Review ◽  
Glasgow Coma Scale ◽  
Subarachnoid Haemorrhage ◽  
Cerebral Vasospasm ◽  
Treatment Options ◽  
Delayed Cerebral Ischemia ◽  
Late Complications ◽  
Aneurysmal Subarachnoid Haemorrhage

SummaryIntroductionAneurysmal subarachnoid haemorrhage (SAH) is associated with high mortality and morbidity. Rebleeding, cerebral vasospasm (VS) with delayed cerebral ischemia (DCI) are major complications after SAH associated with poor neurological outcome.Aim of the studyTo summarize the existing research data on the SAH from incidence, risk factors and clinical presentation to diagnostic, monitoring and treatment options after SAH.Materials and MethodsLiterature review was carried out to identify factors associated with SAH using specific keywords (aneurysmal subarachnoid haemorrhage, rebleeding, cerebral vasospasm, delayed cerebral ischemia) in the PUBMED database. In the time period from 2000 to 2019, 34 full articles were reviewed.ResultsAccording to the literature, the key risk factors for cerebral aneurysms and the SAH are hypertension, smoking, chronic alcohol abuse, family history of intracranial aneurysms in first-degree relatives and female sex. The key risk factor for early complication - rebleeding after SAH - is hypertension. The factors responsible for late complications - cerebral VS and DCI after SAH - are initially lower Glasgow coma scale and higher grades of Fisher scale, where grade IV and III predict cerebral VS in 31–37%. Furthermore, hyperglycaemic state, hyponatremia, hypotension and cerebral hypoperfusion, increased level of Troponin correlate with the incidence of cerebral VS and DCI. Although the golden standard to detect cerebral VS is digital subtraction angiography, CT angiography has become a routine examination. Transcranial doppler sonography is recommended and regional cerebral oximetry also seems to be promising. To avoid rebleeding for wide-necked, gigantic aneurysms or when SAH is combined with intraparenchymal hematoma, surgical clipping is preferred. For posterior circulation aneurisms, poor grade SAH and patients with age >70 years superior is endovascular treatment. To avoid late complications, the pharmacological method is used with Nimodipine.ConclusionsSAH is still associated with poor clinical outcome due to the development of early and late complications. The highest risk patients are those with low Glasgow coma scale and high grades of Fisher scale. Timely performed obliteration methods of the ruptured aneurysm are crucial and Nimodipine is the main agent to prevent cerebral VS and DCI.

Symptomatic cerebral vasospasm manifested 18 days after aneurysmal subarachnoid haemorrhage

1993 ◽  
Vol 15 (3) ◽  
pp. 209-211 ◽  
Author(s):  
Takakazu Kawamata ◽  
Nobuhiko Aoki ◽  
Tatsuo Sakai ◽  
Koji Arai
Keyword(s):  
Subarachnoid Haemorrhage ◽  
Cerebral Vasospasm ◽  
Aneurysmal Subarachnoid Haemorrhage

Treatment of cerebral vasospasm following aneurysmal subarachnoid haemorrhage: a systematic review and meta-analysis

2016 ◽  
Vol 27 (8) ◽  
pp. 3333-3342 ◽  
Author(s):  
Grégoire Boulouis ◽  
Marc Antoine Labeyrie ◽  
Jean Raymond ◽  
Christine Rodriguez-Régent ◽  
Anne Claire Lukaszewicz ◽  
...  
Keyword(s):  
Systematic Review ◽  
Subarachnoid Haemorrhage ◽  
Cerebral Vasospasm ◽  
Meta Analysis ◽  
Aneurysmal Subarachnoid Haemorrhage

scholarly journals Intra-arterial nimodipine for the treatment of vasospasm due to aneurysmal subarachnoid hemorrhage

2016 ◽  
Vol 30 (4) ◽  
pp. 461-466
Author(s):  
A. Chiriac ◽  
Georgiana Ion ◽  
N. Dobrin ◽  
Z. Faiyad ◽  
I. Poeată
Keyword(s):  
Subarachnoid Hemorrhage ◽  
Subarachnoid Haemorrhage ◽  
Cerebral Vasospasm ◽  
Aneurysmal Subarachnoid Hemorrhage ◽  
Aneurysmal Subarachnoid Haemorrhage

Abstract The cerebral vasospasm is still considered the most devastating complication for the patients with aneurysmal subarachnoid haemorrhage. The aim of this study was to evaluate the efficiency of intra-arterial nimodipine administration in cerebral vasospasm diminutions and outcome of the patients.

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