Analysis of a short tandem repeat locus on chromosome 19 (D19S253)

1996 ◽  
Vol 108 (5) ◽  
pp. 256-258 ◽  
Author(s):  
F. De Stefano ◽  
L. Casarino ◽  
M. G. Costa ◽  
G. Bruni ◽  
A. Mannucci ◽  
...  
Keyword(s):  
Tandem Repeat ◽  
Short Tandem Repeat ◽  
Short Tandem Repeat Locus ◽  
Chromosome 19 ◽  
Tandem Repeat Locus ◽  
Repeat Locus ◽  
Short Tandem

Parentally imprinted allele typing at a short tandem repeat locus in intron 1a of imprinted gene KCNQ1

2006 ◽  
Vol 8 (3) ◽  
pp. 139-143 ◽  
Author(s):  
Hong-De Xu ◽  
Emiko Naito ◽  
Koji Dewa ◽  
Masaaki Fukuda ◽  
Hirokazu Sumi ◽  
...  
Keyword(s):  
Tandem Repeat ◽  
Short Tandem Repeat ◽  
Short Tandem Repeat Locus ◽  
Tandem Repeat Locus ◽  
Imprinted Gene ◽  
Repeat Locus ◽  
Short Tandem

Turkish population data on the short tandem repeat locus TPOX

1998 ◽  
Vol 111 (2) ◽  
pp. 105-106 ◽  
Author(s):  
B. Vural ◽  
M. Poda ◽  
E. Atlioglu ◽  
Ö. Kolusayin ◽  
A. Cenani ◽  
...  
Keyword(s):  
Tandem Repeat ◽  
Short Tandem Repeat ◽  
Population Data ◽  
Turkish Population ◽  
Short Tandem Repeat Locus ◽  
Tandem Repeat Locus ◽  
Repeat Locus ◽  
Short Tandem

A new allele at the short tandem repeat locus HumF13A01

1997 ◽  
Vol 110 (5) ◽  
pp. 284-285 ◽  
Author(s):  
B. Glock ◽  
D. W. M. Schwartz ◽  
E. M. Schwartz-Jungl ◽  
G. H. Thorwartl ◽  
E. M. Dauber ◽  
...  
Keyword(s):  
Tandem Repeat ◽  
Short Tandem Repeat ◽  
Short Tandem Repeat Locus ◽  
Tandem Repeat Locus ◽  
Repeat Locus ◽  
Short Tandem

Band shift analysis of three base-pair repeat alleles in the short tandem repeat locus D12S391

1998 ◽  
Vol 93 (2-3) ◽  
pp. 79-88 ◽  
Author(s):  
C.P Phillips ◽  
D Syndercombe Court ◽  
M.V Lareu ◽  
J Hasskamp ◽  
A Carracedo
Keyword(s):  
Tandem Repeat ◽  
Base Pair ◽  
Short Tandem Repeat ◽  
Short Tandem Repeat Locus ◽  
Band Shift ◽  
Tandem Repeat Locus ◽  
Shift Analysis ◽  
Repeat Locus ◽  
Short Tandem

scholarly journals Analysis of an “off-ladder” allele at the Penta D short tandem repeat locus

2015 ◽  
Vol 14 (4) ◽  
pp. 15096-15101
Author(s):  
Y.L. Yang ◽  
J.G. Wang ◽  
D.X. Wang ◽  
W.Y. Zhang ◽  
X.J. Liu ◽  
...  
Keyword(s):  
Tandem Repeat ◽  
Short Tandem Repeat ◽  
Short Tandem Repeat Locus ◽  
Tandem Repeat Locus ◽  
Repeat Locus ◽  
Short Tandem

scholarly journals TH01, a Tetrameric Short Tandem Repeat Locus in the Tyrosine Hydroxylase Gene: Association with Myocardial Hypertrophy and Death from Myocardial Infarction?

2005 ◽  
Vol 21 (1) ◽  
pp. 9-13 ◽  
Author(s):  
Michael Klintschar ◽  
Uta-Dorothee Immel ◽  
Dankwart Stiller ◽  
Manfred Kleiber
Keyword(s):  
Myocardial Infarction ◽  
Blood Pressure ◽  
Tyrosine Hydroxylase ◽  
Tandem Repeat ◽  
Short Tandem Repeat ◽  
Myocardial Hypertrophy ◽  
Short Tandem Repeat Locus ◽  
Tandem Repeat Locus ◽  
Repeat Locus ◽  
Short Tandem

TH01 is a tetrameric short tandem repeat locus located in intron 01 of the tyrosine hydroxylase gene. The tyrosine hydroxylase catalyzes the hydroxylation of L-tyrosine to L-DOPA and is the rate limiting enzyme in the synthesis of catecholamines like noradrenaline or adrenaline, which are pivotal in the regulation of blood pressure. In a clinical study a strong correlation between alleles *9.3 and *10 and essential hypertension was observed ([2] Hypertension 32: 676–682). To further investigate this association, we typed TH01 in 296 autopsy cases and correlated the genotypes to the heart weight as parameter for myocardial hypertrophy. No significant correlation was observed. Moreover, dividing the studied cases into 2 groups, one including 172 casualties from hypertension-associated diseases (myocardial infarction, left heart failure, aortic aneurysm, spontaneous intracerebral bleeding and cerebral infarction) and one consisting of 124 cases of death unrelated to hypertension, revealed similar allelic frequencies for both groups. Our data thus suggest that TH01 long alleles appear not to lead to a significant increase in the incidence of myocardial hypertrophy or other hypertension associated diseases. This could be explained by a relatively small impact of the TH01 genotype on the blood pressure or by counteraction of another mechanism related to catecholamines and their effect on the human body.

Sign in / Sign up

Export Citation Format

Share Document