Unmarried mothers as a high-risk group for adverse pregnancy outcomes

1990 ◽  
Vol 15 (1) ◽  
pp. 35-44 ◽  
Author(s):  
Feroz Ahmed
Keyword(s):  
High Risk ◽  
Pregnancy Outcomes ◽  
Risk Group ◽  
High Risk Group ◽  
Adverse Pregnancy Outcomes ◽  
Unmarried Mothers ◽  
Adverse Pregnancy

scholarly journals Cohort profile: targeted antenatal screening for haemoglobinopathies in Basel

BMJ Open ◽  
2020 ◽  
Vol 10 (7) ◽  
pp. e035735
Author(s):  
Gabriela Amstad Bencaiova ◽  
Franziska Geissler ◽  
Irene Hoesli
Keyword(s):  
High Risk ◽  
Pregnant Women ◽  
Risk Group ◽  
Iron Status ◽  
First Trimester ◽  
High Risk Group ◽  
University Hospital ◽  
Pregnancy Cohort ◽  
Haemoglobin Variant ◽  
Adverse Pregnancy

PurposeThe pregnancy cohort was established to examine the prevalence and variety of haemoglobinopathies in a high-risk group of pregnant women.ParticipantsThe pregnancy cohort is located in the Department of Obstetrics and Antenatal Care, University Hospital of Basel. The pregnant women were recruited in the first trimester between June 2015 and May 2019. Family origin questionnaires were used to screen pregnant women for the risk of a haemoglobin variant. Based on the questionnaire, pregnant women were divided into two groups: women with a high risk and women with a low risk of a haemoglobin variant. In women with a high risk, red blood cell indices, iron status and chromatography were conducted.Findings to date1785 pregnant women were recruited. Out of the 1785 women, 929 were identified as a part of the high-risk group. Due to the missing data of 74 pregnant women with a high risk, the final analysis was conducted in the remaining 855 women. The prevalence of haemoglobinopathies in the high-risk group was 14.5% (124/855).Future plansThis cohort will be used to: (1) implement the screening in prenatal care in Basel; (2) recommend the screening among pregnant women with a high risk of a haemoglobin variant in Switzerland; (3) improve prenatal and neonatal care in patients with a haemoglobin variant; (4) examine adverse pregnancy outcomes in women with a haemoglobin variant and (5) reduce maternal and neonatal morbidity and mortality in the future.Trial registration numberClinicalTrials.gov Registry (NCT04029142).

scholarly journals Perceptions and Practice of Preconception Care by Healthcare Workers and High-Risk Women in South Africa: A Qualitative Study

Healthcare ◽  
2021 ◽  
Vol 9 (11) ◽  
pp. 1552
Author(s):  
Winifred Chinyere Ukoha ◽  
Ntombifikile Gloria Mtshali
Keyword(s):  
South Africa ◽  
High Risk ◽  
Qualitative Study ◽  
Pregnancy Outcomes ◽  
Healthcare Workers ◽  
Preconception Care ◽  
Adverse Pregnancy Outcomes ◽  
High Risk Women ◽  
Reproductive Life ◽  
Adverse Pregnancy

Preconception care is biomedical, behavioural, and social health interventions provided to women and couples before conception. This service is sometimes prioritised for women at high risk for adverse pregnancy outcomes. Evidence revealed that only very few women in Africa with severe chronic conditions receive or seek preconception care advice and assessment for future pregnancy. Thus, this study aimed to explore the perceptions and practice of preconception care by healthcare workers and high-risk women in Kwa-Zulu-Natal, South Africa. This exploratory, descriptive qualitative study utilised individual in-depth interviews to collect data from 24 women at high risk of adverse pregnancy outcomes and five healthcare workers. Thematic analysis was conducted using Nvivo version 12. Five main themes that emerged from the study include participants’ views, patients’ access to information, practices, and perceived benefits of preconception care. The healthcare workers were well acquainted with the preconception care concept, but the women had inconsistent acquaintance. Both groups acknowledge the role preconception care can play in the reduction of maternal and child mortality. A recommendation is made for the healthcare workers to use the ‘One key’ reproductive life plan question as an entry point for the provision of preconception care.

Adverse Pregnancy Outcomes In High Risk Sickle Cell Women

Blood ◽  
2013 ◽  
Vol 122 (21) ◽  
pp. 2218-2218
Author(s):  
Pankhoori Saraf ◽  
Sari H Jacoby ◽  
Shailja Shah ◽  
Habib Nazir ◽  
Martin Gimovsky ◽  
...  
Keyword(s):  
High Risk ◽  
Sickle Cell ◽  
Pregnancy Outcomes ◽  
Placenta Previa ◽  
Mode Of Delivery ◽  
Adverse Pregnancy Outcomes ◽  
Acute Chest Syndrome ◽  
Childbearing Age ◽  
Fetal Outcomes ◽  
Adverse Pregnancy

Abstract Background Life expectancy in patients with sickle cell disease (SCD) has increased with the institution of newborn screening, antibiotics and Hydroxyurea (HU). Prior studies have reported maternal mortality rate to be 2.2 times that of normal pregnancies. With improved high risk obstetrical services and hematological care, more women with SCD are choosing to carry a pregnancy (P). In order to see if outcomes have improved, we performed a review of women with SCD who had recent P at our hospital with a focus on maternal and fetal outcomes. Methods Patients (pts) were identified by a chart review of all women of childbearing age followed at both the Comprehensive Sickle Cell Center and the high risk obstetrics clinic. Data included: genotypes of SCD, fetal complications, P outcomes, transfusions (T), hospital admissions, previous HU use. Results 71 pregnancies were identified in 53 women from 2008 to 2013. Pregnancy outcomes See Table 1. Live births rates were equal in both GR I and GR II. The mean gestational age (weeks) in GR I was 35.13 and GR II 38.28 (p=0.0077) with more preterm births in GR I 16/36 (44%) compared to GR II 2/18 (11%). The most common mode of delivery was C-section in both GR I and II. Reasons for C- section were fetal distress 60% (20), repeat C-section 27% (9), other (5% or less) for breech, elective, preeclampsia, placenta previa. There were equal numbers of induced and spontaneous labor in each group. Complications in GR I 8/36 (22%) and GR II 2/18(11%) included PIH, Chorioamniotis, placenta previa, death (cardiac arrest). Fetal outcomes Low birth weight occurred in 20/33(61%) of GR I and 3/18(17%) of GR II (p= 0.0016) births. Other complications (41 % of births) including IUGR, meconium aspiration, oligohydramnios and Apgar scores <7 @ 1 min occurred equally in both GRs. Maternal outcomes: During P mean values for events in GR I and GR II respectively were: transfusions 5.56 units (U) and 1.22 U (p=0.0022), admission for vasoocclusive crisis (VOC) 3.33/pt and 1.44/pt (p=0.0173). Other complications were urinary tract infection (7), pneumonia (4), acute chest syndrome (4), cardiomyopathy (1), renal failure (1), hepatic crisis (2), DVT (1). Six patients were on HU pre- pregnancy (PP). In these patients 13 simple blood T were required PP and 56 during P (p=0.0297). VOC events increased from 13 PP to 35 during P (p=0.1011). 2 patient required exchange T during P. Conclusion Despite improved antenatal care for SCD women, P remains a high risk event for mother and fetus, with lower birth weights and more preterm deliveries in SS/SB 0 thal pts compared to SC/SB+ thal. Prior use of HU PP was not protective. New insights and studies are warranted to understand the pathophysiology of SCD causing adverse pregnancy outcomes and possible effects of HU withdrawal. Disclosures: No relevant conflicts of interest to declare.

scholarly journals Maternal glycemic parameters and adverse pregnancy outcomes among high-risk pregnant women

2019 ◽  
Vol 7 (1) ◽  
pp. e000774
Author(s):  
Yanwei Zheng ◽  
Yun Shen ◽  
Susu Jiang ◽  
Xiaojing Ma ◽  
Jiangshan Hu ◽  
...  
Keyword(s):  
High Risk ◽  
Pregnant Women ◽  
Pregnancy Outcomes ◽  
Fasting Glucose ◽  
Characteristic Curve ◽  
Tolerance Test ◽  
Adverse Pregnancy Outcomes ◽  
Oral Glucose ◽  
Logistic Regression Models ◽  
Adverse Pregnancy

ObjectiveWe aimed to investigate the association between maternal glycemic parameters and adverse pregnancy outcomes among high-risk pregnant women.Research design and methodsA total of 1976 high-risk pregnant women were enrolled between 2015 and 2017. All participants received a 75 g oral glucose tolerance test during the 24–30 gestational weeks and complete birth and delivery information was collected. Adverse pregnancy outcomes were defined as premature birth, birth weight >90th percentile, primary cesarean section, and pre-eclampsia. Logistic regression models were used to assess the association between five maternal glycemic parameters during pregnancy (fasting glucose, 1-hour glucose, 2-hour glucose, HbA1c, and serum 1,5-anhydroglucitol (1,5-AG)) and adverse pregnancy outcomes.ResultsOf 1976 participants, 498 were diagnosed with gestational diabetes. The multivariable-adjusted ORs of adverse pregnancy outcomes for each one unit increase (1 mmol/L, 1%, or 1 µg/mL) were 2.32 (95% CI 1.85 to 2.92) for fasting glucose, 1.07 (95% CI 1.01 to 1.15) for 1-hour glucose, 1.03 (95% CI 0.96 to 1.10) for 2-hour glucose, 1.77 (95% CI 1.34 to 2.33) for HbA1c, and 0.96 (95% CI 0.94 to 0.98) for 1,5-AG, respectively. When all five glycemic parameters were simultaneously entered into the multivariable-adjusted model, only fasting glucose was significantly associated with total and individual adverse pregnancy outcomes. Receiver operating characteristic curve showed that fasting glucose plus any one of other four glycemic parameters had significantly enhanced the sensitivity of detecting adverse pregnancy outcomes.ConclusionsFasting glucose at 24–30 gestational weeks was strongly associated with adverse pregnancy outcomes. Fasting glucose combined with one additional glycemic measurement showed non-inferiority indicating that post-load glycemic measurement was not necessary in detecting adverse pregnancy outcomes among high-risk pregnant women.

scholarly journals Young adolescent girls are at high risk for adverse pregnancy outcomes in sub-Saharan Africa: an observational multicountry study

BMJ Open ◽  
2016 ◽  
Vol 6 (6) ◽  
pp. e011783 ◽  
Author(s):  
Ghyslain Mombo-Ngoma ◽  
Jean Rodolphe Mackanga ◽  
Raquel González ◽  
Smaila Ouedraogo ◽  
Mwaka A Kakolwa ◽  
...  
Keyword(s):  
High Risk ◽  
Adolescent Girls ◽  
Pregnancy Outcomes ◽  
Adverse Pregnancy Outcomes ◽  
Young Adolescent ◽  
Sub Saharan Africa ◽  
Sub Saharan ◽  
Adverse Pregnancy ◽  
Young Adolescent Girls

scholarly journals Tissue factor pathway inhibitor for prediction of placenta-mediated adverse pregnancy outcomes in high-risk women: AngioPred study

PLoS ONE ◽  
2017 ◽  
Vol 12 (3) ◽  
pp. e0173596 ◽  
Author(s):  
Aurélie Di Bartolomeo ◽  
Céline Chauleur ◽  
Jean-Christophe Gris ◽  
Céline Chapelle ◽  
Edouard Noblot ◽  
...  
Keyword(s):  
High Risk ◽  
Tissue Factor ◽  
Pregnancy Outcomes ◽  
Tissue Factor Pathway Inhibitor ◽  
Adverse Pregnancy Outcomes ◽  
High Risk Women ◽  
Tissue Factor Pathway ◽  
Adverse Pregnancy
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