Nuclear motion corrections to the binding energy in hydrogen

1967 ◽  
Vol 202 (1) ◽  
pp. 425-435 ◽  
Author(s):  
H. Grotch ◽  
D. R. Yennie
Keyword(s):  
Binding Energy ◽  
Nuclear Motion ◽  
Motion Corrections

Ab initiocalculation of nuclear motion corrections to the geometries of water, methanol and silanol

1991 ◽  
Vol 73 (2) ◽  
pp. 335-348 ◽  
Author(s):  
Jörg-Rüdiger Hill ◽  
Joachim Sauer ◽  
Reinhart Ahlrichs
Keyword(s):  
Nuclear Motion ◽  
Motion Corrections

Controlled modulation of the binding energy of impurity states in a quantum-well system

1996 ◽  
Vol 166 (4) ◽  
pp. 447-448 ◽  
Author(s):  
Vladimir I. Belyavskii ◽  
Yurii V. Kopaev ◽  
N.V. Kornyakov
Keyword(s):  
Binding Energy ◽  
Quantum Well ◽  
Impurity States

Excitonic quasimolecules containing of two quantum dots

2016 ◽  
pp. 4024-4028 ◽  
Author(s):  
Sergey I. Pokutnyi ◽  
Wlodzimierz Salejda
Keyword(s):  
Quantum Dots ◽  
Binding Energy ◽  
Exchange Interaction ◽  
Coulomb Interaction ◽  
Silicate Glass ◽  
Glass Matrix ◽  
Silicate Glass Matrix

The possibility of occurrence of the excitonic  quasimolecule formed of spatially separated electrons and holes in a nanosystem that consists  of  CuO quantum dots synthesized in a silicate glass matrix. It is shown that the major contribution to the excitonic quasimolecule binding energy is made by the energy of the exchange interaction of electrons with holes and this contribution is much more substantial than the contribution of the energy of Coulomb interaction between the electrons and holes.

Destabilizing the Structural Integrity of SARS-CoV2 Receptor Proteins by Curcumin Along with Hydroxychloroquine: An Insilco Approach for a Combination Therapy

2020 ◽  
Author(s):  
Akhileshwar Srivastava ◽  
Divya Singh
Keyword(s):  
Binding Energy ◽  
Combination Therapy ◽  
Receptor Binding ◽  
Structural Integrity ◽  
Binding Domain ◽  
Receptor Binding Domain ◽  
Receptor Proteins ◽  
Main Protease ◽  
The Stability ◽  
Therapeutic Activities

Presently, an emerging disease (COVID-19) has been spreading across the world due to coronavirus (SARS-CoV2). For treatment of SARS-CoV2 infection, currently hydroxychloroquine has been suggested by researchers, but it has not been found enough effective against this virus. The present study based on in silico approaches was designed to enhance the therapeutic activities of hydroxychloroquine by using curcumin as an adjunct drug against SARS-CoV2 receptor proteins: main-protease and S1 receptor binding domain (RBD). The webserver (ANCHOR) showed the higher protein stability for both receptors with disordered score (<0.5). The molecular docking analysis revealed that the binding energy (-24.58 kcal/mol) of hydroxychloroquine was higher than curcumin (-20.47 kcal/mol) for receptor main-protease, whereas binding energy of curcumin (<a>-38.84</a> kcal/mol) had greater than hydroxychloroquine<a> (-35.87</a> kcal/mol) in case of S1 receptor binding domain. Therefore, this study suggested that the curcumin could be used as combination therapy along with hydroxychloroquine for disrupting the stability of SARS-CoV2 receptor proteins

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