Hepatotoxicity from paraaminobenzoic acid

Marie Borum; Ephraim Nsien; Hyman Zimmerman

doi:10.1007/bf01296627

Hepatotoxicity from paraaminobenzoic acid

Digestive Diseases and Sciences ◽

10.1007/bf01296627 ◽

1991 ◽

Vol 36 (12) ◽

pp. 1793-1793 ◽

Cited By ~ 4

Author(s):

Marie Borum ◽

Ephraim Nsien ◽

Hyman Zimmerman

Keyword(s):

Paraaminobenzoic Acid

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4957906 Pharmaceutical compositions containing a derivative of paraaminobenzoic acid as an active ingredient

General Pharmacology The Vascular System ◽

10.1016/0306-3623(91)90554-j ◽

1991 ◽

Vol 22 (2) ◽

pp. xii

Keyword(s):

Active Ingredient ◽

Paraaminobenzoic Acid

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CLINICAL EFFECTS OF PARAAMINOBENZOIC ACID IN VITILIGO

Archives of Dermatology ◽

10.1001/archderm.1944.01510080044011 ◽

1944 ◽

Vol 49 (2) ◽

pp. 132 ◽

Cited By ~ 1

Author(s):

L. G. BEINHAUER

Keyword(s):

Clinical Effects ◽

Paraaminobenzoic Acid

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Method of spectrophotometric determination of novocaine in the presence of paraaminobenzoic acid

Pharmaceutical Chemistry Journal ◽

10.1007/bf02344109 ◽

1977 ◽

Vol 11 (4) ◽

pp. 573-575

Author(s):

T. T. Likhota

Keyword(s):

Spectrophotometric Determination ◽

Paraaminobenzoic Acid

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THE EFFECT OF CALCIUM PANTOTHENATE AND PARAAMINOBENZOIC ACID ON GRAY HAIR IN MAN

The American Journal of the Medical Sciences ◽

10.1097/00000441-194409000-00006 ◽

1944 ◽

Vol 208 (3) ◽

pp. 315-320 ◽

Cited By ~ 4

Author(s):

HAROLD BRANDALEONE ◽

ELIZABETH MAIN ◽

J. MURRAY STELLE

Keyword(s):

Calcium Pantothenate ◽

Gray Hair ◽

Paraaminobenzoic Acid

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PARAAMINOBENZOIC ACID AS A SUNSCREEN

Archives of Dermatology ◽

10.1001/archderm.1953.01540120112016 ◽

1953 ◽

Vol 68 (6) ◽

pp. 728 ◽

Cited By ~ 1

Author(s):

ALEXANDER A. FISHER

Keyword(s):

Paraaminobenzoic Acid

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Luminescence properties of rare-earth (Eu3+ and Tb3+) complexes with paraaminobenzoic acid and 1,10-phenanthroline incorporated into a silica matrix by sol-gel method

Materials Research Bulletin ◽

10.1016/s0025-5408(98)00133-0 ◽

1998 ◽

Vol 33 (10) ◽

pp. 1517-1525 ◽

Cited By ~ 70

Author(s):

B Yan ◽

H Zhang ◽

S Wang ◽

J Ni

Keyword(s):

Rare Earth ◽

Sol Gel ◽

Silica Matrix ◽

Luminescence Properties ◽

Gel Method ◽

Sol Gel Method ◽

Paraaminobenzoic Acid

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Cu(II), Mn(II), Ni(II) Complexes of Mixed Amodiaquine and Paraaminobenzoic acid: Synthesis, Characterization, Antimicrobial and Toxicological Activities in Wister rats

Al-Qadisiyah Journal Of Pure Science ◽

10.29350/qjps.2020.25.4.1184 ◽

2020 ◽

Vol 25 (4) ◽

pp. 7-20

Author(s):

Mercy Bamigboye ◽

Ikechukwu P. Ejidike ◽

Abdulbasit A. Aliyu

Keyword(s):

Metal Ion ◽

Acid Synthesis ◽

Antimicrobial Activities ◽

Octahedral Geometry ◽

The Body ◽

Spectroscopic Techniques ◽

Zone Of Inhibition ◽

E Coli ◽

Paraaminobenzoic Acid ◽

Acid Produce

Four novel metal complexes of mixed amodiaquine and paraaminobenzoic acid have been synthesized using a standard method and confirmed by results of some physicochemical and spectroscopic techniques. Antimicrobial activities have been carried out on the complexes against some selected organisms: (antibacterial organisms: K. pneumonia, B. subtilis, E. coli, S. aureus, P. aeruginosa and S. faecalis) and (antifungal organisms: Candida albicans, Aspergillus niger and Penicillium chrysogenum) to determine their effectiveness. The complexes were evaluated for their toxicity level in wister rats. The Amodiaquine and Paraaminobenzoic acid produce complexes in ratio 1:1:1 in coordination with the metal ion. Octahedral geometry has been proposed for all the complexes. The complexes were found to be non-electrolytic in nature. The complexes were observed to be more active than their free ligands as determined by their zone of inhibition (nm). The complexes have been proved to be less toxic to the body.

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