New prospects in the creation of gas-cooled fast reactors with a short doubling time, using dissociating N2O4

1974 ◽  
Vol 37 (1) ◽  
pp. 687-698 ◽  
Author(s):  
A. K. Krasin ◽  
V. B. Nesterenko
Keyword(s):  
Doubling Time ◽  
Fast Reactors ◽  
The Creation ◽  
Short Doubling Time

Effect of Pin and Subassembly Heterogenity in Sodium Void Worth Calculations

2010 ◽  
Author(s):  
G. Raghu Kumar ◽  
C. P. Reddy ◽  
V. Sathyamoorthy
Keyword(s):  
Monte Carlo Code ◽  
Reactor Accident ◽  
Fast Reactors ◽  
Neutron Spectra ◽  
Energy Scenario ◽  
Higher Power ◽  
Breeding Ratio ◽  
Short Doubling Time ◽  
Undesirable Feature ◽  
Total Sodium

Metal fuelled sodium cooled fast reactors are known to have high breeding ratio and short doubling time. Due to these features they play a very important role in the energy scenario, where higher power growth is required. Large sodium cooled fast reactors have positive sodium void coefficient, which is considered to be undesirable feature even though reactor safety can be established for all design based accidents like loss of flow and transient over power accidents. These types of fast reactors, which have harder neutron spectra are having higher sodium void coefficient compared to ceramic fuelled fast reactors. In many of the safety analysis the total sodium void is calculated and it is used in the safely evaluation. However the sodium in the metal fuelled reactor has got three parts, namely bonding sodium, coolant sodium and the sodium in the inter space of subassembly hexagonal cans. In the reactor accident scenario the behavior of these three components of sodium will be different and will effect the sequence of the accident. The finer details, of the fuel sub assembly, are modeled in to Monte Carlo code and the sodium void coefficient is calculated for each of the component for the fuel zones. This study will be helpful in improving safety of the reactor and also reducing the conservatism in the safely features.

The principal technical problems and prospects for the creation of gas-cooled fast reactors with a power of 1200?1500 MW using a dissociating coolant

1978 ◽  
Vol 44 (2) ◽  
pp. 138-143
Author(s):  
A. K. Krasin ◽  
V. B. Nesterenko ◽  
B. E. Tverkovkin ◽  
V. F. Zelenskii ◽  
V. A. Naumov ◽  
...  
Keyword(s):  
Fast Reactors ◽  
Technical Problems ◽  
The Creation

What should the doubling time of fast reactors be?

1971 ◽  
Vol 31 (3) ◽  
pp. 925-927
Author(s):  
V. V. Orlov
Keyword(s):  
Doubling Time ◽  
Fast Reactors

scholarly journals Omicron strain spreads with the doubling time of 3.2-3.6 days in South Africa province of Gauteng that achieved herd immunity to Delta variant

2021 ◽  
Author(s):  
Frederic Grabowski ◽  
Marek Kochańczyk ◽  
Tomasz Lipniacki
Keyword(s):  
South Africa ◽  
Phylogenetic Analysis ◽  
Linear Regression ◽  
Doubling Time ◽  
Herd Immunity ◽  
The Novel ◽  
Gauteng Province ◽  
The World ◽  
Log Linear ◽  
Short Doubling Time

Omicron, the novel, highly mutated SARS-CoV-2 Variant of Concern (belonging to the Pango lineage B.1.1.529), was first collected on November 8, 2021, in Gauteng province of South Africa. By the end of November 2021 it has spread towards fixation in Gauteng and was detected on all continents. Based on data collected till December 7, 2021, we showed the exponential growth of the Omicron variant over the four-week period in Gauteng (November 8-December 5, 2021) with the doubling time equal 3.38 day [CI 95%: 3.18-3.61 day]. Log-linear regression suggests that the spread began around October 10, 2021, however due to stochasticity in the initial spread this estimate is likely inaccurate. Phylogenetic analysis indicates that the Omicron strain started to diverge in between October 28 and November 5, 2021. This implies that the hidden spread of Omicron before October 10, 2021 (which would suggest slower strain growth) is unlikely. The very short doubling time of Omicron in Gauteng, a province that has reached herd immunity to the Delta variant (implied by the decrease of the weekly number of cases between July and October, 2021, at no significant mobility restrictions), suggests that Omicron will cause abrupt outbreaks of COVID-19 epidemics across the world, and will become the (temporarily) dominant strain.

scholarly journals BCR-ABL1 doubling times more reliably assess the dynamics of CML relapse compared with the BCR-ABL1 fold rise: implications for monitoring and management

Blood ◽  
2012 ◽  
Vol 119 (18) ◽  
pp. 4264-4271 ◽  
Author(s):  
Susan Branford ◽  
David T. Yeung ◽  
Jodi A. Prime ◽  
Soo-Young Choi ◽  
Ju-hee Bang ◽  
...  
Keyword(s):  
Doubling Time ◽  
Blast Crisis ◽  
Chronic Phase ◽  
Molecular Response ◽  
Clinical Context ◽  
Measurement Interval ◽  
Clinical Resistance ◽  
Doubling Times ◽  
Short Doubling Time ◽  
Independent Cohort

Abstract Rising BCR-ABL1 transcripts indicate potential loss of imatinib response in CML. We determined whether the BCR-ABL1 doubling time could distinguish nonadherence from resistance as the cause of lost response. Distinct groups were examined: (1) acquired clinical resistance because of blast crisis and/or BCR-ABL1 mutations; and (2) documented imatinib discontinuation/interruption. Short doubling times occurred with blast crisis (median, 9.0 days; range, 6.1-17.6 days; n = 12 patients), relapse after imatinib discontinuation in complete molecular response (median, 9.0 days; range, 6.9-26.5 days; n = 17), and imatinib interruption during an entire measurement interval (median, 9.4 days; range, 4.2-17.6 days; n = 12; P = .72). Whereas these doubling times were consistently short and indicated rapid leukemic expansion, fold rises were highly variable: 71-, 9.5-, and 10.5-fold, respectively. The fold rise depended on the measurement interval, whereas the doubling time was independent of the interval. Longer doubling times occurred for patients with mutations who maintained chronic phase (CP: median, 48 days; range, 17.3-143 days; n = 29; P < .0001). Predicted short and long doubling times were validated on an independent cohort monitored elsewhere. The doubling time revealed major differences in kinetics according to clinical context. Long doubling times observed with mutations in CP allow time for intervention. A short doubling time for a patient in CP should raise the suspicion of nonadherence.

The role of affect in feelings of obligation

2020 ◽  
Vol 43 ◽  
Author(s):  
Stefen Beeler-Duden ◽  
Meltem Yucel ◽  
Amrisha Vaish
Keyword(s):  
Positive Emotions ◽  
The Creation ◽  
Sense Of Obligation

Abstract Tomasello offers a compelling account of the emergence of humans’ sense of obligation. We suggest that more needs to be said about the role of affect in the creation of obligations. We also argue that positive emotions such as gratitude evolved to encourage individuals to fulfill cooperative obligations without the negative quality that Tomasello proposes is inherent in obligations.

1423: The Impact of Gleason Score on the Predictive Value of PSA Doubling Time

2007 ◽  
Vol 177 (4S) ◽  
pp. 469-470 ◽  
Author(s):  
Stephen A. Boorjian ◽  
Sameer A. Siddiqui ◽  
Brant A. Inman ◽  
Jeffrey M. Slezak ◽  
R. Jeffrey Karnes ◽  
...  
Keyword(s):  
Gleason Score ◽  
Predictive Value ◽  
Doubling Time ◽  
Psa Doubling Time ◽  
The Impact

865: Comparison of Preoperative PSA Velocity or PSA Doubling Time as a Predictor of Outcome after Radical Prostatectomy

2006 ◽  
Vol 175 (4S) ◽  
pp. 279-279
Author(s):  
Stacy Loeb ◽  
Xiaoying Yu ◽  
Kimberly A. Roehl ◽  
Robert B. Nadler ◽  
Theresa Graif ◽  
...  
Keyword(s):  
Radical Prostatectomy ◽  
Doubling Time ◽  
Psa Doubling Time ◽  
Psa Velocity

1385: Stratification of Patient Risk Based on PSA Doubling Time Following Radical Retropubic Prostatectomy

2006 ◽  
Vol 175 (4S) ◽  
pp. 447-447
Author(s):  
Matthew K. Tollefson ◽  
Jeffrey M. Slezak ◽  
Horst Zincke ◽  
Michael L. Blute
Keyword(s):  
Doubling Time ◽  
Radical Retropubic Prostatectomy ◽  
Patient Risk ◽  
Retropubic Prostatectomy ◽  
Psa Doubling Time
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