Are the disparate pharmacological profiles of competitive and un-competitive NMDA antagonists due to different baseline activities of distinct glutamatergic pathways? (Hypothesis)

1993 ◽  
Vol 94 (1) ◽  
pp. 1-10 ◽  
Author(s):  
M. L. Carlsson
Keyword(s):  
Nmda Antagonists ◽  
Glutamatergic Pathways ◽  
Competitive Nmda Antagonists ◽  
Pharmacological Profiles

ChemInform Abstract: Design, Synthesis, SAR, and Biological Evaluation of Highly Potent Benzimidazole-Spaced Phosphono-α-amino Acid Competitive NMDA Antagonists of the AP-6 Type.

ChemInform ◽  
2010 ◽  
Vol 32 (35) ◽  
pp. no-no
Author(s):  
Reinhardt B. Baudy ◽  
Horace Fletcher III ◽  
John P. Yardley ◽  
Margaret M. Zaleska ◽  
Donna R. Bramlett ◽  
...  
Keyword(s):  
Amino Acid ◽  
Biological Evaluation ◽  
Nmda Antagonists ◽  
Design Synthesis ◽  
Competitive Nmda Antagonists

Potent quinoxaline-spaced phosphono .alpha.-amino acids of the AP-6 type as competitive NMDA antagonists: synthesis and biological evaluation

1993 ◽  
Vol 36 (3) ◽  
pp. 331-342 ◽  
Author(s):  
Reinhardt B. Baudy ◽  
Lynne P. Greenblatt ◽  
Ivo L. Jirkovsky ◽  
Mary Conklin ◽  
Ralph J. Russo ◽  
...  
Keyword(s):  
Amino Acids ◽  
Biological Evaluation ◽  
Nmda Antagonists ◽  
Synthesis And Biological Evaluation ◽  
Competitive Nmda Antagonists

Non-competitive NMDA antagonists, FR115427 and MK801, enhance neuronal survival in primary culture

1995 ◽  
Vol 185 (2) ◽  
pp. 107-110 ◽  
Author(s):  
Yoshiko Ueda ◽  
Kiyotaka Katsuta ◽  
Hajime Nakanishi ◽  
Keizo Yoshida
Keyword(s):  
Primary Culture ◽  
Neuronal Survival ◽  
Nmda Antagonists ◽  
Competitive Nmda Antagonists

Involvement of the GluN2C subunit in the behavioral syndrome induced by non-competitive NMDA antagonists

2018 ◽  
Vol 28 ◽  
pp. S37 ◽  
Author(s):  
M. Tarrés-Gatius ◽  
C. Scorza ◽  
L. Miquel-Rio ◽  
X. López-Hill ◽  
N. Santana ◽  
...  
Keyword(s):  
Behavioral Syndrome ◽  
Nmda Antagonists ◽  
Competitive Nmda Antagonists
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