Neurosecretory material passing into the hypophysial portal system in the human infundibulum, and its foetal development

1963 ◽  
Vol 25 (3) ◽  
pp. 310-324 ◽  
Author(s):  
U. K. Rinne
Keyword(s):  
Portal System ◽  
Neurosecretory Material ◽  
Foetal Development ◽  
Hypophysial Portal

THE RELATION BETWEEN THE HYPOTHALAMIC NEUROSECRETION AND THE CORTICOTROPHIN RELEASE IN EXPERIMENTAL CONDITIONS

1960 ◽  
Vol XXXIV (I) ◽  
pp. 8-18 ◽  
Author(s):  
E. Kivalo ◽  
U. K. Rinne
Keyword(s):  
Paraventricular Nucleus ◽  
Median Eminence ◽  
Supraoptic Nucleus ◽  
Acute Stress ◽  
Neurosecretory Material ◽  
Experimental Conditions ◽  
Hypothalamic Cells ◽  
The One ◽  
Hypophysial Portal ◽  
Acth Release

ABSTRACT Acute stress, chronic stress plus hydration, cortisone treatment, cortisone treatment plus dehydration were used as methods of investigation and the relation between the neurosecretory activity of the hypothalamic supraoptic nucleus and paraventricular nucleus and the neurosecretory material around the hypophysial portal vessels of the median eminence on the one hand and the corticotrophin release on the other hand, has been studied in the rat. Whereas stress stimulates both the activity of the above mentioned cells of the hypothalamus and the ACTH release, stress plus hydration causes a depression of these hypothalamic cells but nevertheless causes a marked ACTH release. Cortisone inhibits the activity of the cells in the supraoptic nucleus and the paraventricular nucleus as well as the ACTH release whereas cortisone plus dehydration causes stimulation but inhibits the ACTH release. In some stress and cortisone treatment groups the variations of the neurosecretory material around the hypophysial portal vessels and of the ACTH release were found to show a correlation. It is concluded that the activity of the cells of the supraoptic nucleus and the paraventricular nucleus and the ACTH release do not seem to have any definite connection, whereas some observations indicate that the neurosecretory material in the region of the median eminence around the hypophysial portal vessels may have some significance in ACTH release.

scholarly journals Some Observations on the Cytology of the Adenohypophysis of the Non-parous Female Rabbit

1959 ◽  
Vol s3-100 (51) ◽  
pp. 463-482
Author(s):  
M. ALLANSON ◽  
C. L. FOSTER ◽  
G. MENZIES
Keyword(s):  
Proteolytic Enzymes ◽  
Portal System ◽  
Pars Intermedia ◽  
Pars Tuberalis ◽  
Pars Distalis ◽  
Electron Microscopic ◽  
Female Rabbit ◽  
Lipid Inclusions ◽  
Cytological Characteristics ◽  
Hypophysial Portal

Evidence is presented which suggests that in this animal the pars tuberalis may have some function in addition to acting as a bed for the hypophysial portal system, since its cells appear rich in RNA. The granules of the cells of the pars intermedia are shown to be PAS-positive, but this reaction, unlike that of the basiphil cells of the pars distalis proper and the zona tuberalis, is readily prevented by pretreatment of sections with proteolytic enzymes. A study of the basiphil cells of the pars distalis proper and of the zona tuberalis, based on cytological characteristics, size, and shape, provides some evidence for the existence of two, and possibly three, kinds of basiphil cell. The lipid inclusions of the adenohypophysial cells and their relationship to the Golgi elements are described, together with some brief preliminary observations upon the electron microscopic characteristics of acidophil and basiphil cells.

THE HYPOPHYSIAL PORTAL SYSTEM OF VESSELS IN MAN

1954 ◽  
Vol 39 (3) ◽  
pp. 219-230 ◽  
Author(s):  
G. P. Xuereb ◽  
Marjorie M. L. Prichard ◽  
P. M. Daniel
Keyword(s):  
Portal System ◽  
Hypophysial Portal

HYPOTHALAMO-NEUROHYPOPHYSIAL NEUROSECRETION AFTER THE EXTIRPATION OF VARIOUS ENDOCRINE GLANDS

1963 ◽  
Vol 42 (2) ◽  
pp. 293-299 ◽  
Author(s):  
H. Arko ◽  
E. Kivalo ◽  
U. K. Rinne
Keyword(s):  
Median Eminence ◽  
Vascular System ◽  
Pituitary Hormones ◽  
Bilateral Adrenalectomy ◽  
Neurosecretory Material ◽  
Experimental Conditions ◽  
Paraventricular Nuclei ◽  
Aldehyde Fuchsin ◽  
Hypophysial Portal

ABSTRACT The possible role of the hypothalamo-neurohypophysial system in regulating the release of the anterior pituitary hormones was studied in the rabbit and the rat. Thyroidectomy, gonadectomy and uni- and bilateral adrenalectomy were the experimental conditions used. The neurosecretory material (N. S. M.) was demonstrated by the aldehyde-fuchsin (AF) technique. Distinct differences were not seen in the different groups of rabbits on account of the great variation between individuals. In the rats, the thyroidectomy and gonadectomy groups often had slightly more N. S. M. in the median eminence around the portal vessels than the controls. Slight depletion of N. S. M. in the infundibular process was observed in unilaterally adrenalectomized rats. N. S. M. passing into the portal vascular system showed a tendency to increase. In the bilateral adrenalectomy group, N. S. M. was reduced in the supraoptic and paraventricular nuclei, in the hypothalamo-hypophysial tract and in the infundibular process. However, considerably more numerous neurosecretory nerve fibres passing towards the portal vessels than in the controls were found in the median eminence of this group. The conclusion drawn was that N. S. M. entering the hypophysial portal vessels in the median eminence may be of significance in the regulation of corticotrophin release.

Sign in / Sign up

Export Citation Format

Share Document