Quantitative determination of trace amounts of carbonyl compounds. II. Colorimetric analysis for acetaldehyde

1959 ◽  
Vol 47 (2) ◽  
pp. 210-213 ◽  
Author(s):  
Earl W. Malmberg ◽  
Boris Weinstein ◽  
D. L. Fishel ◽  
Ronald A. Krause
Keyword(s):  
Quantitative Determination ◽  
Carbonyl Compounds ◽  
Colorimetric Analysis

Chromatographic Procedure for Determination of Reserpine in Tablets. II. Collaborative Study

1969 ◽  
Vol 52 (1) ◽  
pp. 113-115
Author(s):  
Susan Barkan
Keyword(s):  
Quantitative Determination ◽  
Collaborative Study ◽  
Chromatographic Column ◽  
Colorimetric Analysis ◽  
Acid Base ◽  
Water Layers ◽  
Suitable Amount ◽  
Chromatographic Procedure ◽  
Tablet Formulations

Abstract A method is described for the quantitative determination of reserpine in tablet formulations. A suitable amount of tablet material is triturated with dimethylsulfoxide (DMSO), incorporated onto Celite, and transferred to a chromatographic column containing acid, base, and water layers. The reserpine is eluted with chloroform and quantitated spectrophotometrically. Duplicate results from 16 collaborators averaged 100.7% recovery as determined by UV, 98.8% recovery determined by colorimetric analysis. The method is recommended for adoption as official first action.

Development of test placers for blister colorimetric analysis of phosphate ions

2020 ◽  
pp. 24-29
Author(s):  
Aleksey Zhevnerov ◽  
Ravil Baybyekov ◽  
Sergey Belopuhov ◽  
Andrey Bochkarev
Keyword(s):  
Quantitative Determination ◽  
Phosphate Concentration ◽  
Colorimetric Determination ◽  
Colorimetric Analysis ◽  
Ion Concentrations ◽  
Phosphate Ion ◽  
Phosphate Ions ◽  
Preliminary Preparation ◽  
Colorimetric Reaction

Variants of the compositions of a series of placers for visually blister colorimetric determination of phosphate ion concentrations in a blister cell (tablet for tablets) containing a mixture of reagents are proposed. The placers allow quantitative determination of the phosphate concentration in various objects without preliminary preparation of reagent solutions. The application of reagents to the surface of silica gel makes it possible to isolate all reagents until a chemical reaction occurs. The composition and conditions of deposition of crystalline substances – reagents capable of providing a sufficiently high acidity with the addition of a few drops of a solution and an optimal reducing agent for blister conditions were optimized. The visual colorimetric reaction is carried out under conditions when the volume of the added solution is 0.1–0.2 ml.

scholarly journals Modern methods for regulation nicotine containing products

2019 ◽  
Vol 81 (2) ◽  
pp. 196-201
Author(s):  
E. V. Gnuchih ◽  
M. V. Shkiduk ◽  
A. G. Mirgorodskaya ◽  
N. N. Matyuhina ◽  
T. A. Don
Keyword(s):  
Quality Control ◽  
Quantitative Determination ◽  
Carbonyl Compounds ◽  
High Performance ◽  
Comprehensive Evaluation ◽  
Heating System ◽  
Modern Methods ◽  
Innovative Products ◽  
Electrospray Source

Issues of assessing the content of carbonyl compounds in the aerosol of innovative nicotine-containing products: nicotine delivery systems of various designs (LUXLITE, VON ERL My, iKuu i200) and electric tobacco heating system iQOS, by high-performance liquid chromatography/mass spectrometry. At the international level (CORESTA, ISO/TC 126), a lot of work is being done to create methods for quality control of nicotine-containing products. Requirements for nicotine-containing products are not regulated within the EAEU. The monitoring of world studies to determine the content of toxic and conditionally toxic components of aerosol NSP, carried out using the method of machine Smoking. Vniitti IS developing a methodology for comprehensive evaluation of innovative nicotine-containing products on the basis of modern methods of product quality control. Of particular interest is the determination of the content of carbonyl compounds in the aerosol generated by SDN and ESNT, which started in the laboratory of tobacco production technology within the Eurasian Economic Union. The results of machine Smoking according to the canadian intensive method, ISO method, VNIITTI method, standard and experimental CORESTA methods are analyzed. Developed testing methodology and collection of aerosol-nicotine produce using a laboratory five-CERULEAN Smoking machines SM 405. The technique of quantitative determination of carbonyl compounds using high-performance liquid chromatomass spectrometry LCMS/MS by detection at an electrospray source in the negative polarity mode on analytical equipment was validated: chromatograph Thermo Scientific Dionex UltiMate 3000 and mass spectrometer TSQ Quantiva. Validation of methods for collecting and determining the content of carbonyl compounds (formaldehyde, acetaldehyde and acrolein) in the aerosol of nicotine-containing products of various types allowed to obtain reliable data to establish the potential of innovative products to reduce the risk compared with traditional cigarettes. Experimental data on the quantitative determination of carbonyl compounds in the NSP aerosol were obtained. Further research will focus on the development of evidence-based safety requirements for innovative types of nicotine-containing products.

Quantitative determination of longitudinal and transverse cross-relaxation rates

1999 ◽  
Vol 96 (9/10) ◽  
pp. 1608-1615
Author(s):  
T. E. Malliavin ◽  
H. Desvaux ◽  
M. A. Delsuc
Keyword(s):  
Quantitative Determination ◽  
Cross Relaxation ◽  
Relaxation Rates
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