Idiopathic portal hypertension associated with high serum titer of antoantibodies and liver dysfunction

1996 ◽  
Vol 31 (1) ◽  
pp. 123-128 ◽  
Author(s):  
Katsuhito Mori ◽  
Eiyi Ishimura ◽  
Hitoshi Goto ◽  
Shigeichi Shoji ◽  
Shuichi Seki ◽  
...  
Keyword(s):  
Portal Hypertension ◽  
Liver Dysfunction ◽  
Idiopathic Portal Hypertension ◽  
High Serum ◽  
Serum Titer

Predominant T helper 1 cells in patients with idiopathic portal hypertension

2000 ◽  
Vol 15 (11) ◽  
pp. 1312-1317 ◽  
Author(s):  
Katsutoshi Tokushige ◽  
Katsumi Yamauchi ◽  
Tatsuji Komatsu ◽  
Ken Takasaki ◽  
Naoaki Hayashi
Keyword(s):  
Portal Hypertension ◽  
Idiopathic Portal Hypertension ◽  
T Helper ◽  
T Helper 1 ◽  
T Helper 1 Cells

Novel rat model of repetitive portal venous embolization mimicing human non-cirrhotic idiopathic portal hypertension

2016 ◽  
Vol 54 (08) ◽  
Author(s):  
S Klein ◽  
C Hinüber ◽  
K Hittatiya ◽  
R Schierwagen ◽  
FE Uschner ◽  
...  
Keyword(s):  
Portal Hypertension ◽  
Rat Model ◽  
Idiopathic Portal Hypertension

Delayed periportal enhancement: a characteristic finding on contrast ultrasound in idiopathic portal hypertension

2011 ◽  
Vol 6 (2) ◽  
pp. 511-519 ◽  
Author(s):  
Hitoshi Maruyama ◽  
Taro Shimada ◽  
Hiroyuki Ishibashi ◽  
Masanori Takahashi ◽  
Hidehiro Kamesaki ◽  
...  
Keyword(s):  
Portal Hypertension ◽  
Idiopathic Portal Hypertension ◽  
Characteristic Finding ◽  
Contrast Ultrasound

Development of Portal Vein Thrombosis Complicating Idiopathic Portal Hypertension

1985 ◽  
Vol 88 (4) ◽  
pp. 1034-1040 ◽  
Author(s):  
Kunihiko Ohnishi ◽  
Masayuki Saito ◽  
Hidetaka Terabayashi ◽  
Fumio Nomura ◽  
Kunio Okuda
Keyword(s):  
Portal Hypertension ◽  
Portal Vein ◽  
Portal Vein Thrombosis ◽  
Idiopathic Portal Hypertension ◽  
Vein Thrombosis

The Clinical Entity of Idiopathic Portal Hypertension: A Review of 17 Cases

1983 ◽  
Vol 1 (2) ◽  
pp. 107-113 ◽  
Author(s):  
Kotohito Takeshige ◽  
Sadahiro Yamamoto
Keyword(s):  
Portal Hypertension ◽  
Idiopathic Portal Hypertension ◽  
Clinical Entity

scholarly journals A Case of Idiopathic Portal Hypertension. Improvement of Portal Venous Flow to the Liver Following Hassab's Operation.

1998 ◽  
Vol 31 (9) ◽  
pp. 1991-1995
Author(s):  
Hidefumi Baba ◽  
Katsunori Tanaka ◽  
Shigenao Kan ◽  
Fumio Suzuki ◽  
Hitoshi Otaka ◽  
...  
Keyword(s):  
Portal Hypertension ◽  
Idiopathic Portal Hypertension ◽  
Portal Venous Flow ◽  
Venous Flow

scholarly journals Divergences in Macrophage Activation Markers Soluble CD163 and Mannose Receptor in Patients With Non-cirrhotic and Cirrhotic Portal Hypertension

2021 ◽  
Vol 12 ◽  
Author(s):  
Nikolaj Worm Ørntoft ◽  
Michel Blé ◽  
Anna Baiges ◽  
Jose Ferrusquia ◽  
Virginia Hernández-Gea ◽  
...  
Keyword(s):  
Portal Hypertension ◽  
Liver Disease ◽  
Macrophage Activation ◽  
Mannose Receptor ◽  
Idiopathic Portal Hypertension ◽  
Healthy Controls ◽  
Activation Markers ◽  
Vein Thrombosis ◽  
Soluble Cd163 ◽  
Cirrhotic Patients

IntroductionMacrophages are involved in development and progression of chronic liver disease and portal hypertension. The macrophage activation markers soluble (s)CD163 and soluble mannose receptor (sMR), are associated with portal hypertension in patient with liver cirrhosis but never investigated in patients with non-cirrhotic portal hypertension. We hypothesized higher levels in cirrhotic patients with portal hypertension than patients with non-cirrhotic portal hypertension. We investigated sCD163 and sMR levels in patients with portal hypertension due to idiopathic portal hypertension (IPH) and portal vein thrombosis (PVT) in patients with and without cirrhosis.MethodsWe studied plasma sCD163 and sMR levels in patients with IPH (n = 26), non-cirrhotic PVT (n = 20), patients with cirrhosis without PVT (n = 31) and with PVT (n = 17), and healthy controls (n = 15).ResultsMedian sCD163 concentration was 1.51 (95% CI: 1.24–1.83) mg/L in healthy controls, 1.96 (95% CI: 1.49–2.56) in patients with non-cirrhotic PVT and 2.16 (95% CI: 1.75–2.66) in patients with IPH. There was no difference between non-cirrhotic PVT patients and healthy controls, whereas IPH patients had significantly higher levels than controls (P < 0.05). The median sCD163 was significantly higher in the cirrhotic groups compared to the other groups, with a median sCD163 of 6.31 (95% CI: 5.16–7.73) in cirrhotics without PVT and 5.19 (95% CI: 4.18–6.46) with PVT (P < 0.01, all). Similar differences were observed for sMR.ConclusionSoluble CD163 and sMR levels are elevated in patients with IPH and patients with cirrhosis, but normal in patients with non-cirrhotic PVT. This suggests that hepatic macrophage activation is more driven by the underlying liver disease with cirrhosis than portal hypertension.

Sign in / Sign up

Export Citation Format

Share Document