Influence of small cardioactive peptide (b) on the efficiency of synaptic transmission and the excitability of command neurons of the defensive behavior of the edible snail

1992 ◽  
Vol 22 (2) ◽  
pp. 148-152
Author(s):  
N. I. Bravarenko
Keyword(s):  
Synaptic Transmission ◽  
Defensive Behavior ◽  
Edible Snail ◽  
Command Neurons

scholarly journals Reciprocal Stimulation of Decay Between Serotonergic Facilitation and Depression of Synaptic Transmission

2008 ◽  
Vol 100 (2) ◽  
pp. 1113-1126 ◽  
Author(s):  
Sun Hee Cho Lee ◽  
Karen Taylor ◽  
Franklin B. Krasne
Keyword(s):  
Protein Kinase ◽  
Synaptic Transmission ◽  
Protein Kinase A ◽  
The Other ◽  
Command Neurons ◽  
Wide Range ◽  
History Of ◽  
Depressive States ◽  
Kinase A ◽  
Stimulation Of

Serotonin can produce multiple, contradictory modulatory effects on strength of synaptic transmission in both vertebrate and invertebrate nerve circuits. In crayfish, serotonin (5-HT) can both facilitate and depress transmission to lateral giant escape command neurons; however, which effect is manifest during application, as well as the sign and duration of effects that may continue long after 5-HT washout, may depend on history of application as well as on concentration. We report that protein kinase A (PKA) signaling is essential to the production of facilitation but depression is mediated by non-cAMP/PKA signaling pathways. However, we unexpectedly found that PKA activity is essential for the decay of depression when serotonin is washed out. This, and evidence from the effects of a variety of serotonin application regimens, suggest that facilitatory and depressive states coexist and compete and that the decay of each is dependent on stimulation by the other. A computational model that incorporates these assumptions can account for and rationalize the varied effects of a wide range of serotonin application regimens.

Effect of Chronic Administration of Chlorpromazine on Electrical Parameters of Command Neurons in Edible Snail

2005 ◽  
Vol 139 (3) ◽  
pp. 272-274
Author(s):  
T. Kh. Gainutdinova ◽  
A. V. Meshchaninova ◽  
V. V. Andrianov ◽  
D. I. Silant’eva ◽  
Kh. L. Gainutdinov
Keyword(s):  
Chronic Administration ◽  
Edible Snail ◽  
Command Neurons ◽  
Electrical Parameters
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