Enhanced development of conditioned reaction during stimulation of amygdaloid complex in rats

1986 ◽  
Vol 16 (6) ◽  
pp. 497-498
Author(s):  
N. V. Vol'f ◽  
S. B. Tsvetovskii ◽  
R. Yu. Il'yuchenok
Keyword(s):  
Amygdaloid Complex ◽  
Conditioned Reaction ◽  
Stimulation Of

Plasma 17-hydroxycorticosteroid levels during electrical stimulation of the amygdaloid complex in conscious monkeys

1958 ◽  
Vol 196 (1) ◽  
pp. 44-48 ◽  
Author(s):  
John W. Mason
Keyword(s):  
Electrical Stimulation ◽  
Large Dose ◽  
Rhesus Monkeys ◽  
Hypothalamic Stimulation ◽  
Amygdaloid Complex ◽  
Implanted Electrodes ◽  
Stimulation Of

Substantial plasma 17-OH-CS elevations invariably occurred during electrical stimulation of the amygdaloid complex in unanesthetized rhesus monkeys through chronically implanted electrodes. No evidence of localization of this effect within anatomical subdivisions of the amygdaloid complex was observed. Stimulation of the amygdala elicited plasma 17-OH-CS elevations (20 µg %/hr.) equal to those occurring with hypothalamic stimulation or injection of a large dose of ACTH (16 mg/kg), while no elevations were observed during putamen stimulation or under normal conditions.

Effects of septal lesions on behavior elicited by stimulation of the amygdaloid complex

1976 ◽  
Vol 17 (1) ◽  
pp. 1-16 ◽  
Author(s):  
Israel Lieblich ◽  
Jacob Yitzhaky ◽  
Edna Cohen
Keyword(s):  
Amygdaloid Complex ◽  
Septal Lesions ◽  
Stimulation Of

On the Instrumental Conditioned Reaction Evoked by Electrical Stimulation of the Hypothalamus

Science ◽  
1959 ◽  
Vol 130 (3371) ◽  
pp. 336-337 ◽  
Author(s):  
W. WYRWICKA ◽  
C. DOBRZECKA ◽  
R. TARNECKI
Keyword(s):  
Electrical Stimulation ◽  
Conditioned Reaction ◽  
Stimulation Of

EFFECTS OF AMYGDALOID LESIONS ON REGIONAL BRAIN RNA BASE RATIOS

1969 ◽  
Vol 45 (2) ◽  
pp. 207-214 ◽  
Author(s):  
B. E. ELEFTHERIOU ◽  
R. L. CHURCH ◽  
A. J. ZOLOVICK ◽  
R. L. NORMAN ◽  
M. L. PATTISON
Keyword(s):  
Actinomycin D ◽  
Normal Animal ◽  
Adenosine Monophosphate ◽  
Amygdaloid Complex ◽  
Guanosine Monophosphate ◽  
Neural Function ◽  
Regional Brain ◽  
Bilateral Lesions ◽  
Uridine Monophosphate ◽  
Stimulation Of

SUMMARY Bilateral lesions produced by electrocoagulation in the basolateral and medial amygdaloid nuclei, subtotal amygdalectomy as well as implants of actinomycin D and cholesterol were all found to have profound effects on brain ribonucleic acid (RNA) base percentages and ratios. The most consistent effect was that on the pituitary and was produced by all treatments. Generally, the hypothalamus and frontal cortex showed varying effects due to the treatments, but the cerebellum uniformly showed no responses to the various treatments. Lesions placed in the medial amygdaloid complex and subtotal amygdalectomy had the greatest effect in changing the RNA base ratio. The bases adenosine monophosphate (AMP), cytidine monophosphate (CMP), guanosine monophosphate (GMP), and uridine monophosphate (UMP) were found to be the most affected. The newly synthesized RNA was found to be rich in UMP and deficient in AMP and CMP when compared to normal animal brain tissue. The assumption is made that lesions in the amygdala bring about an activation or stimulation of a genomic nature to produce specific RNA for a particular neural function.

scholarly journals Learning-induced plasticity in the barrel cortex is disrupted by inhibition of layer 4 somatostatin-containing interneurons

2020 ◽  
Author(s):  
G Dobrzanski ◽  
A Lukomska ◽  
R Zakrzewska ◽  
A Posluszny ◽  
D Kanigowski ◽  
...  
Keyword(s):  
Cerebral Cortex ◽  
Conditioned Stimulus ◽  
Barrel Cortex ◽  
Specific Cell ◽  
Conditioned Reaction ◽  
Functional Representation ◽  
Layer 4 ◽  
Plastic Changes ◽  
Plastic Change ◽  
Stimulation Of

ABSTRACTLearning-related plasticity in the cerebral cortex is linked to the action of disinhibitory circuits of interneurons. Pavlovian conditioning, in which stimulation of the vibrissae is used as conditioned stimulus, induces plastic enlargement of the cortical functional representation of vibrissae activated during conditioning, visualized with [14C]-2-deoxyglucose (2DG). Using layer-specific, cell-selective DREADD transductions, we examined the involvement of somatostatin- (SOM-INs) and vasoactive intestinal peptide (VIP-INs)-containing interneurons in the development of learning-related plastic changes. We injected DREADD-expressing vectors into layer IV (L4) barrels or layer II/III (L2/3) areas corresponding to activated vibrissae. The activity of interneurons was modulated during training, and 2DG maps were obtained 24 h later. In mice with L4 but not L2/3 SOM-INs suppressed during conditioning, the plastic change of whisker representation and the conditioned reaction were absent. No effect of inhibiting VIP-INs was found. We report that the activity of L4 SOM-INs is indispensable for learning-induced plastic change.

Sign in / Sign up

Export Citation Format

Share Document