Influence of the genotype on the formation of aggressive and submissive behavior in mice

1988 ◽  
Vol 18 (1) ◽  
pp. 38-43 ◽  
Author(s):  
N. N. Kudryavtseva ◽  
A. P. Sitnikov
2018 ◽  
Author(s):  
Anila Sadaf Mubashir ◽  
Syeda Shahida Batool

2015 ◽  
Vol 5 (1) ◽  
Author(s):  
Elimelech Nesher ◽  
Igor Koman ◽  
Moshe Gross ◽  
Tatiana Tikhonov ◽  
Maryia Bairachnaya ◽  
...  

2007 ◽  
Vol 1 (1) ◽  
pp. 60-72 ◽  
Author(s):  
Gordon Josephson ◽  
Valerie Whiffen

A model of depressive symptoms in gay men is tested that links gender-related personality traits (agency and unmitigated communion) to peer harassment, self-discrepancies in agency, and cold-submissive interpersonal behavior, all of which were reported in previous research to contribute to depression. A sample of 510 gay men was recruited through the Internet. The integrated model was tested using half of the sample and validated with the other half. Significant zero order correlations between the gender-related personality traits and depressive symptoms were mediated by unassured-submissive behavior and self-discrepancies in agency. Recalled peer harassment was linked directly with depressive symptoms and indirectly through unassured-submissive interpersonal behavior.


1970 ◽  
Vol 27 (2) ◽  
pp. 195-198 ◽  
Author(s):  
Carl W. Lawrence ◽  
Jack R. Haynes

Effects of epinephrine and nor-epinephrine on social dominance behavior in 24 male C57BL/6J mice were investigated. The social dominance hierarchy was created by placing pairs of Ss in a linear maze. The only way S could get to the goal box was by pushing the opposing S out. The dominant S pushed the submissive S out of the maze. After the dominance hierarchy was established, each S was placed in the dominance situation under each of the drug conditions, epinephrine and nor-epinephrine. The results showed that all conditions were significantly different from each other, with the greatest amount of dominance behavior being shown under nor-epinephrine and the greatest submissive behavior under epinephrine. It was concluded that epinephrine and nor-epinephrine may have differential effects on social dominance behavior.


2015 ◽  
Vol 17 (3) ◽  
pp. 287-293 ◽  

Social anxiety disorder (SAD) is a highly prevalent and disabling disorder with key behavioral traits of social fearfulness, social avoidance, and submissiveness. Here we argue that hormonal systems play a key role in mediating social anxiety, and so may be important in SAD. Hormonal alterations, often established early in development through the interaction between biological and psychological factors (eg, genetic predisposition x early trauma), predispose to socially fearful, avoidant, and submissive behavior. However, whereas gene variants and histories of trauma persist, hormonal systems can be remodeled over the course of life. Hormones play a key role during the periods of all sensitive developmental windows (ie, prenatal, neonatal, puberty, aging), and are capable of opening up new developmental windows in adulthood. Indeed, the developmental plasticity of our social brain, and thus of social behavior in adulthood, critically depends on steroid hormones such as testosterone and peptide hormones such as oxytocin. These steroid and peptide hormones in interaction with social experiences may have potential for reprogramming the socially anxious brain. Certainly, single administrations of oxytocin and testosterone in humans reduce socially fearful, avoidant, and submissive behavior. Such work may ultimately lead to new approaches to the treatment of SAD.


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