Synapse ultrastructure of the initial axon segment of the pyramidal neuron

1986 ◽  
Vol 16 (1) ◽  
pp. 1-6 ◽  
Author(s):  
T. A. Bragina
Keyword(s):  
Pyramidal Neuron ◽  
Initial Axon Segment ◽  
Synapse Ultrastructure

scholarly journals 3D Ultrastructure of Synaptic Inputs to Distinct GABAergic Neurons in the Mouse Primary Visual Cortex

2020 ◽  
Author(s):  
Yang-Sun Hwang ◽  
Catherine Maclachlan ◽  
Jérôme Blanc ◽  
Anaëlle Dubois ◽  
Carl C H Petersen ◽  
...  
Keyword(s):  
Visual Cortex ◽  
Primary Visual Cortex ◽  
Pyramidal Neuron ◽  
Cell Types ◽  
Gabaergic Neurons ◽  
Inhibitory Synapses ◽  
Synaptic Inputs ◽  
Neuronal Types ◽  
The Difference ◽  
Ultrastructure Of Synapses

Abstract Synapses are the fundamental elements of the brain’s complicated neural networks. Although the ultrastructure of synapses has been extensively studied, the difference in how synaptic inputs are organized onto distinct neuronal types is not yet fully understood. Here, we examined the cell-type-specific ultrastructure of proximal processes from the soma of parvalbumin-positive (PV+) and somatostatin-positive (SST+) GABAergic neurons in comparison with a pyramidal neuron in the mouse primary visual cortex (V1), using serial block-face scanning electron microscopy. Interestingly, each type of neuron organizes excitatory and inhibitory synapses in a unique way. First, we found that a subset of SST+ neurons are spiny, having spines on both soma and dendrites. Each of those spines has a highly complicated structure that has up to eight synaptic inputs. Next, the PV+ and SST+ neurons receive more robust excitatory inputs to their perisoma than does the pyramidal neuron. Notably, excitatory synapses on GABAergic neurons were often multiple-synapse boutons, making another synapse on distal dendrites. On the other hand, inhibitory synapses near the soma were often single-targeting multiple boutons. Collectively, our data demonstrate that synaptic inputs near the soma are differentially organized across cell types and form a network that balances inhibition and excitation in the V1.

scholarly journals Digital Implementation of the Two-Compartmental Pinsky–Rinzel Pyramidal Neuron Model

2018 ◽  
Vol 12 (1) ◽  
pp. 47-57 ◽  
Author(s):  
Elahe Rahimian ◽  
Soheil Zabihi ◽  
Mahmood Amiri ◽  
Bernabe Linares-Barranco
Keyword(s):  
Pyramidal Neuron ◽  
Neuron Model ◽  
Digital Implementation

scholarly journals Postnatal development of synaptic structure proteins in pyramidal neuron axon initial segments in monkey prefrontal cortex

2009 ◽  
Vol 514 (4) ◽  
pp. 353-367 ◽  
Author(s):  
Dianne A. Cruz ◽  
Emily M. Lovallo ◽  
Steven Stockton ◽  
Matthew Rasband ◽  
David A. Lewis
Keyword(s):  
Prefrontal Cortex ◽  
Postnatal Development ◽  
Pyramidal Neuron ◽  
Synaptic Structure ◽  
Monkey Prefrontal Cortex ◽  
Axon Initial Segments

scholarly journals Local Control of Postinhibitory Rebound Spiking in CA1 Pyramidal Neuron Dendrites

2010 ◽  
Vol 30 (18) ◽  
pp. 6434-6442 ◽  
Author(s):  
G. A. Ascoli ◽  
S. Gasparini ◽  
V. Medinilla ◽  
M. Migliore
Keyword(s):  
Local Control ◽  
Pyramidal Neuron ◽  
Postinhibitory Rebound ◽  
Rebound Spiking ◽  
Ca1 Pyramidal Neuron

Effects of Chronic Donepezil Treatment and Cholinergic Deafferentation on Parietal Pyramidal Neuron Morphology

2009 ◽  
Vol 17 (1) ◽  
pp. 177-191 ◽  
Author(s):  
Paola De Bartolo ◽  
Francesca Gelfo ◽  
Laura Mandolesi ◽  
Francesca Foti ◽  
Debora Cutuli ◽  
...  
Keyword(s):  
Pyramidal Neuron ◽  
Neuron Morphology

228 Inhibitory effect of topiramate on abnormal glutamic transmission in the hippocampal CA3 pyramidal neuron of spontaneously epileptic rats (SER)

1997 ◽  
Vol 28 ◽  
pp. S40
Author(s):  
Ryosuke Hanaya ◽  
Masashi Sasa ◽  
Kumatoshi Ishihara ◽  
Tadao Serikawa ◽  
Koji Iida ◽  
...  
Keyword(s):  
Pyramidal Neuron ◽  
Inhibitory Effect ◽  
Hippocampal Ca3

scholarly journals Inositol-1,4,5-trisphosphate receptor-mediated Ca2+waves in pyramidal neuron dendrites propagate through hot spots and cold spots

2009 ◽  
Vol 587 (7) ◽  
pp. 1439-1459 ◽  
Author(s):  
John S. Fitzpatrick ◽  
Anna M. Hagenston ◽  
Daniel N. Hertle ◽  
Keith E. Gipson ◽  
Lisa Bertetto-D'Angelo ◽  
...  
Keyword(s):  
Pyramidal Neuron ◽  
Hot Spots ◽  
Inositol 1,4,5 Trisphosphate ◽  
Cold Spots ◽  
Trisphosphate Receptor
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