Morphometric analysis of synaptic contacts in the anterior limbic cortex in the endogenous psychoses

1992 ◽  
Vol 22 (1) ◽  
pp. 59-65 ◽  
Author(s):  
�. A. Aganova ◽  
N. A. Uranova
Keyword(s):  
Morphometric Analysis ◽  
Limbic Cortex ◽  
Synaptic Contacts ◽  
Endogenous Psychoses ◽  
Anterior Limbic Cortex

A dopamine-sensitive adenylate cyclase in anterior limbic cortex and mesolimbic region of primate brain

1975 ◽  
Vol 96 (2) ◽  
pp. 395-399 ◽  
Author(s):  
Ram K. Mishra ◽  
C. Demirjian ◽  
R. Katzman ◽  
M.H. Makman
Keyword(s):  
Adenylate Cyclase ◽  
Limbic Cortex ◽  
Primate Brain ◽  
Anterior Limbic Cortex

scholarly journals Ultrastructural demonstration of noradrenergic synapses in the rat central nervous system by dopamine-beta-hydroxylase immunocytochemistry.

1981 ◽  
Vol 29 (2) ◽  
pp. 271-280 ◽  
Author(s):  
J A Olschowka ◽  
M E Molliver ◽  
R Grzanna ◽  
F L Rice ◽  
J T Coyle
Keyword(s):  
Central Nervous System ◽  
Synaptic Vesicles ◽  
Limbic Cortex ◽  
Immunocytochemical Localization ◽  
Synaptic Contacts ◽  
Outer Membranes ◽  
Dopamine Beta Hydroxylase ◽  
Granular Vesicles ◽  
Axodendritic Synapses ◽  
Large Granular Vesicles

Noradrenergic (NA) cell bodies and axonal processes were identified in the electron microscope by the immunocytochemical localization of the norepinephrine-synthesizing enzyme, dopamine-beta-hydroxylase (DBH). DBH immunoreactivity, visualized by the peroxidase-antiperoxidase method, was observed in the somata and proximal processes of locus coeruleus neurons and in the distal axons of several NA terminal fields. DBH immunoreactivity is distributed throughout the cytoplasm of the NA neuron, but demonstrates a selective association with endoplasmic reticulum, Golgi apparatus, mitochondrial outer membranes, large granular vesicles, and small, round synaptic vesicles. DBH-positive axonal profiles, typically interspersed between unlabeled dendrites, form two distinct populations: a) thin, unmyelinated intervaricose segments (ca. 0.28 micron) and b) spherical varicosities (ca. 1.00 micron). No DBH-positive varicosities were observed in contact with intracerebral capillaries. In order to determine whether or not NA axons typically form synaptic contacts, a quantitative analysis of selected areas of the diencephalon, cerebellum, and limbic cortex was carried out. More than half (58%) of all DBH-positive varicosities form axodendritic synapses characterized by specialized junctional appositions. The results suggest that NA neurons typically exert their influence on other neurons through highly restricted synaptic contacts.

scholarly journals Morphometry of the effect of increased experience and training on synaptic density in area CA3 of the rat hippocampus.

1979 ◽  
Vol 27 (11) ◽  
pp. 1548-1550 ◽  
Author(s):  
R A Altschuler
Keyword(s):  
Motor Activity ◽  
Morphometric Analysis ◽  
Enriched Environment ◽  
Rat Hippocampus ◽  
Synaptic Density ◽  
Synaptic Contacts ◽  
Total Length ◽  
And Training ◽  
Area Ca3

A morphometric analysis of the effect of differential experiences on synapses was performed in area CA3 of the rat hippocampus. Two methods of quantitation that used a superimposed lattice grid were employed. In the first method squares overlying synapses were measured as a proportion of the total number of squares scanned; in the second method intersections of lattice lines with synapses were counted as a proportion of the total length of lines. Both measures showed that rats which were housed in an enriched environment and received 10 weeks of training had a significant increase in total area of synaptic contacts compared to both nonenriched controls and a croup with increased motor activity.

Sign in / Sign up

Export Citation Format

Share Document