‘Free’ postsynaptic-like densities in normal adult brain: their occurrence, distribution, structure and association with subsurface cisterns

1982 ◽  
Vol 11 (5) ◽  
pp. 693-706 ◽  
Author(s):  
J. Špaček
Keyword(s):  
Adult Brain ◽  
Normal Adult ◽  
Subsurface Cisterns ◽  
Distribution Structure

1H MR Spectroscopic Patterns of Normal Adult Brain

1996 ◽  
Vol 35 (4) ◽  
pp. 435 ◽  
Author(s):  
In Chan Song ◽  
Kee Hyun Chang ◽  
Kwan Hong Min ◽  
Dong Sung Kim ◽  
Moon Hee Han ◽  
...  
Keyword(s):  
Adult Brain ◽  
Normal Adult

Drosophila Pax-6/eyeless is essential for normal adult brain structure and function

2001 ◽  
Vol 46 (2) ◽  
pp. 73-88 ◽  
Author(s):  
P. Callaerts ◽  
S. Leng ◽  
J. Clements ◽  
C. Benassayag ◽  
D. Cribbs ◽  
...  
Keyword(s):  
Brain Structure ◽  
Structure And Function ◽  
Adult Brain ◽  
Normal Adult ◽  
Brain Structure And Function ◽  
And Function

scholarly journals MTR variations in normal adult brain structures using balanced steady-state free precession

2010 ◽  
Vol 53 (3) ◽  
pp. 159-167 ◽  
Author(s):  
Meritxell Garcia ◽  
Monika Gloor ◽  
Oliver Bieri ◽  
Stephan G. Wetzel ◽  
Ernst-Wilhelm Radue ◽  
...  
Keyword(s):  
Steady State ◽  
Steady State Free Precession ◽  
Brain Structures ◽  
Adult Brain ◽  
Normal Adult ◽  
Free Precession

Landmark-Based Morphometrics of the Normal Adult Brain Using MRI

NeuroImage ◽  
2001 ◽  
Vol 13 (5) ◽  
pp. 801-813 ◽  
Author(s):  
S.L. Free ◽  
P. O'Higgins ◽  
D.D. Maudgil ◽  
I.L. Dryden ◽  
L. Lemieux ◽  
...  
Keyword(s):  
Adult Brain ◽  
Normal Adult

scholarly journals Is There Evidence for Myelin Modeling by Astrocytes in the Normal Adult Brain?

2017 ◽  
Vol 11 ◽  
Author(s):  
Alfredo Varela-Echevarría ◽  
Víctor Vargas-Barroso ◽  
Carlos Lozano-Flores ◽  
Jorge Larriva-Sahd
Keyword(s):  
Adult Brain ◽  
Normal Adult

Free amino acids and related substances in human glial tumours and in fetal brain: comparison with normal adult brain

1976 ◽  
Vol 117 (1) ◽  
pp. 105-113 ◽  
Author(s):  
Jeanne-Marie Lefauconnier ◽  
Christiane Portemer ◽  
Fernande Chatagner
Keyword(s):  
Amino Acids ◽  
Free Amino Acids ◽  
Free Amino ◽  
Fetal Brain ◽  
Adult Brain ◽  
Normal Adult ◽  
Related Substances

scholarly journals Involvement of Notch1 Signaling in Neurogenesis in the Subventricular Zone of Normal and Ischemic Rat Brain in Vivo

2009 ◽  
Vol 29 (10) ◽  
pp. 1644-1654 ◽  
Author(s):  
XiaoMei Wang ◽  
XiaoOu Mao ◽  
Lin Xie ◽  
David A Greenberg ◽  
Kunlin Jin
Keyword(s):  
Cell Proliferation ◽  
Signaling Pathway ◽  
Subventricular Zone ◽  
Focal Cerebral Ischemia ◽  
Adult Brain ◽  
Normal Adult ◽  
Proliferating Cells ◽  
Notch1 Signaling ◽  
Notch1 Signaling Pathway

The Notch1 signaling pathway is regarded as one of the main regulators of neural stem cell behavior during development, but its role in the adult brain is less well understood. We found that Notch1 was mainly expressed in doublecortin (DCX)-positive cells corresponding to newborn neurons, whereas the Notch1 ligand, Jagged1, was predominantly expressed in glial fibrillary acidic protein (GFAP)-positive astrocytic cells in the subventricular zone (SVZ) of the normal adult brain. These findings were confirmed by conditional depletion of DCX-positive cells in transgenic mice carrying herpes simplex virus thymidine kinase (HSV-TK) under the control of the DCX promoter. In addition, the activated form of Notch1 (Notch intracellular domain, NICD) and its downstream transcriptional targets, Hes1 and sonic hedgehog (Shh), were also expressed in SVZ cells. Increased activation of Notch1 signaling increased SVZ cell proliferation, whereas inhibiting Notch1 signaling resulted in a reduction of proliferating cells in the SVZ. Levels of NICD, Hes1, and Shh were increased in the SVZ at 4 and 24 h after focal cerebral ischemia. Finally, ischemia-induced cell proliferation in the SVZ was blocked by inhibition of the Notch1 signaling pathway, suggesting that Notch1 signaling may have a key role in normal adult and ischemia-induced neurogenesis.

Sign in / Sign up

Export Citation Format

Share Document