Pentylenetetrazol: Effect on carbaryl-induced changes of serotonin metabolism in pons-medulla of rat brain

1986 ◽  
Vol 6 (8) ◽  
pp. 767-774 ◽  
Author(s):  
Subir K. Ray ◽  
Mrinal K. Poddar
Keyword(s):  
Rat Brain ◽  
Serotonin Metabolism ◽  
Pons Medulla ◽  
Induced Changes

Effect of pentylenetetrazol on the carbaryl-induced changes of serotonin metabolism in rat-brain hypothalamus

1984 ◽  
Vol 4 (5) ◽  
pp. 427-432 ◽  
Author(s):  
S. K. Ray ◽  
M. K. Poddar
Keyword(s):  
Rat Brain ◽  
Adult Male ◽  
Indoleacetic Acid ◽  
Male Rat ◽  
Simultaneous Administration ◽  
Serotonin Metabolism ◽  
Time Intervals ◽  
Hypothalamic Region ◽  
Adult Male Rat ◽  
Induced Changes

Carbaryl (200 mg/kg or 400 mg/kg, p.o.) significantly elevated serotonin (5-HT) (57–109%) and 5-hydroxy-indoleacetic acid (5-HIAA) (60–78%) levels at 1.0 h in the hypothalamic region of adult male rat brain. Further, administration of carbaryl (200 mg/kg, p.o.) for different time intervals (0.5 h, 1.0 h, and 2.0 h) revealed that both 5-HT and 5-HIAA levels elevated maximally at 0.5 h in hypothalamus. These regional 5-HT and 5-HIAA levels were not significantly affected with pentylenetetrazol (PTZ) at any time after its treatment. But simultaneous administration of carbaryl (200 mg/kg, p.o.) and PTZ (60 mg/kg, s.c.) reduced the carbaryl-induced elevation of both 5-HT and 5-HIAA leveis. Measurement of (i) probenecid-induced (200 mg/kg, i.p.) accumulation and (ii) pargyline-induced (75 mg/kg, i.p.) depletion of hypothalamic 5-HIAA level in the absence or presence of carbaryl (200 mg/kg, p.o.) and/or PTZ (60 mg/kg, s.c.) revealed that (a) carbaryl enhanced the synthesis as well as the breakdown of 5-HT, (b) PTZ had no effect on either of these processes of 5-HT, and (c) carbaryl-induced increased catabolism of 5-HT became normal in the presence of PTZ.

Decapitation-induced changes in inositol phosphates in rat brain

1990 ◽  
Vol 167 (3) ◽  
pp. 1294-1301 ◽  
Author(s):  
Teng-Nan Lin ◽  
Grace Y. Sun ◽  
Noel Premkumar ◽  
Ronald A. MacQuarrie ◽  
Steven R. Carter
Keyword(s):  
Rat Brain ◽  
Inositol Phosphates ◽  
Induced Changes

CLOZAPINE INDUCED CHANGES OF ZIF/268 mRNA IN THE RAT BRAIN.

1992 ◽  
Vol 15 ◽  
pp. 454B
Author(s):  
T Chishima ◽  
S. M. Babb ◽  
D. J. Ennulat ◽  
B. M. Cohen
Keyword(s):  
Rat Brain ◽  
Induced Changes

scholarly journals Exercise-Induced Changes in Branched Chain Amino Acid/Aromatic Amino Acid Ratio in the Rat Brain and Plasma

1987 ◽  
Vol 45 (2) ◽  
pp. 243-248
Author(s):  
Koji OKAMURA ◽  
Futoshi MATSUBARA ◽  
Yasuyuki YOSHIOKA ◽  
Noriaki KIKUCHI ◽  
Yuko KIKUCHI ◽  
...  
Keyword(s):  
Amino Acid ◽  
Rat Brain ◽  
Aromatic Amino Acid ◽  
Branched Chain Amino Acid ◽  
Acid Ratio ◽  
Branched Chain ◽  
Exercise Induced ◽  
Induced Changes

Daily variations of serotonin metabolism in the rat brain

1972 ◽  
Vol 43 (2) ◽  
pp. 445-465 ◽  
Author(s):  
Francis Héry ◽  
Evelyne Rouer ◽  
Jacques Glowinski
Keyword(s):  
Rat Brain ◽  
Serotonin Metabolism ◽  
Daily Variations

Dopamine and serotonin metabolism in discrete rat brain nuclei after TRH administration

1992 ◽  
Vol 21 ◽  
pp. D10
Author(s):  
M. Lema ◽  
J. Otero ◽  
A. Lafuente ◽  
G. Cousillas ◽  
J. Marcó
Keyword(s):  
Rat Brain ◽  
Serotonin Metabolism ◽  
Brain Nuclei
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