Gas hold-up in external-loop airlift bioreactors

1995 ◽  
Vol 12 (1-2) ◽  
pp. 21-27 ◽  
Author(s):  
Y. Kawase ◽  
M. Tsujimura ◽  
T. Yamaguchi
Keyword(s):  
External Loop ◽  
Airlift Bioreactors

Mass transfer in external-loop airlift bioreactors using static mixers

1990 ◽  
Vol 68 (1) ◽  
pp. 45-50 ◽  
Author(s):  
Yusuf Chisti ◽  
Michael Kasper ◽  
Murray Moo-Young
Keyword(s):  
Mass Transfer ◽  
Static Mixers ◽  
External Loop ◽  
Airlift Bioreactors

Gas hold-up in external-loop airlift bioreactors

1995 ◽  
Vol 12 (1) ◽  
pp. 21
Author(s):  
Y. Kawase ◽  
M. Tsujimura ◽  
T. Yamaguchi
Keyword(s):  
External Loop ◽  
Airlift Bioreactors

Liquid-phase mixing in external-loop airlift bioreactors

1994 ◽  
Vol 61 (1) ◽  
pp. 49-55 ◽  
Author(s):  
Yoshinori Kawase ◽  
Naoki Omori ◽  
Masanari Tsujimura
Keyword(s):  
Liquid Phase ◽  
Phase Mixing ◽  
External Loop ◽  
Airlift Bioreactors

Hydrodynamics in external-loop airlift bioreactors with static mixers

1997 ◽  
Vol 16 (2) ◽  
pp. 93 ◽  
Author(s):  
M. Gavrilescu ◽  
R. V. Roman ◽  
R. Z. Tudose
Keyword(s):  
Static Mixers ◽  
External Loop ◽  
Airlift Bioreactors

scholarly journals AIRLIFT BIOREACTOR FLUID-DYNAMIC CHARACTERIZATIONFOR THE CULTIVATION OF SHEAR STRESS SENSITIVEMICROORGANISMS

2015 ◽  
Vol 5 (2) ◽  
pp. 639-651 ◽  
Author(s):  
Márcio José Rossi ◽  
FX Nascimento ◽  
AJ Giachini ◽  
VL Oliveira ◽  
A Furigo Jr
Keyword(s):  
Shear Stress ◽  
Ectomycorrhizal Fungi ◽  
Oxygen Transfer ◽  
Fluid Dynamic ◽  
Experimental Studies ◽  
Ectomycorrhizal Fungus ◽  
Airlift Bioreactor ◽  
External Loop ◽  
Airlift Bioreactors ◽  
Superficial Gas Velocity

Airlift bioreactors are considered very efficient for aerobic cultivation of microorganisms. In particular, for the cultivation of filamentous fungi, where low shear rates may be required. In this context, the main aim of this study was to design an airlift bioreactor built with an external loop, adequate for biomass production of microbial organisms, including ectomycorrhizal fungi. A 5-L airlift bioreactor was constructed and experimental studies performed under an air-salt solution system (0.15 mol/L NaCl), in order to characterize the reactor´s fluid-dynamic in relation to the superficial gas velocity (Ug) in the range of 0.001 to 0.020 m/s. In order to evaluate the performance of the reactor, a preliminary assay was conducted with the ectomycorrhizal fungus Rhizopogonnigrescens. Better gas separationreflected in better liquid circulation and higher oxygen transfer (0.0197 1/s at 1 vvm) when compared to an operating, 2.3-L prototype airlift. According to this study, volumetric coefficients for oxygen transfer (kLa) up to 0.020 1/s (specific airflow rates of 1.0 vvm) are sufficient to promote the growth of shear stress sensitive microorganisms, such as ectomycorrhizal fungi.

scholarly journals Mixing Characteristics of External Loop Airlift Bioreactor using Electrical Resistance Tomography

2021 ◽  
Author(s):  
Mian Hamood-Ur-Rehman
Keyword(s):  
Electrical Resistance ◽  
Liquid Velocity ◽  
Mixing Time ◽  
Perforated Plate ◽  
Packed Bed ◽  
Gas Holdup ◽  
External Loop ◽  
Gas Distributor ◽  
Airlift Bioreactors ◽  
Superficial Liquid Velocity

In the present work, a novel packed bed external loop pneumatically agitated airlift bioreactor with an internal gas distributor (perforated plate) between two rolls of packing in the riser was designed and built. This novel approach combines advantages of packed bed and external loop airlift bioreactors. The main objective of this research work was to characterize the hydrodynamic performance of this novel reactor through a non-intrusive flow visualization technique called electrical resistance tomography (ERT). The tomography images, which were generated using a linear back projection algorithm, were employed to explore the effects of different design parameters and operating conditions. These include the effect of the two packing in the riser and the internal gas distributor (perforated plate) installed between the two packing. Other parameters investigated include the effect of sparger configuration, gas flow rate, and liquid height in the bioreactor on the different hydrodynamic parameters such as gas holdup, mixing time, and liquid circulation velocity. Results showed that the gas holdup and mixing time increased in the presence of the gas distributor, while the riser superficial liquid velocity was decreased. Furthermore, gas holdup and mixing time increased, superficial liquid velocity decreased when decreasing liquid height in the reactor, and when using packing or gas distributor between two packings in the riser. These results can be used to improve mixing characteristics in external loop airlift bioreactors for wider range of applications.

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