Analytic estimates of computer design at the structural stage

Many energy saving tasks can be solved thanks to the current advances in LED technology in the production of semiconductor light sources. Modern production of solid-state LEDs guarantees high-precision compliance with the calculated design parameters of illumination devices. This opens up wide opportunities for high-precision control of the lighting parameters of a multicomponent module: light power, a directional pattern and a distribution of illumination. Today, the methodical issues of the preliminary modeling of LED illumination devices with the given parameters are fundamentally solved. There is a shift from manual calculations to computer design and need to develop and select the most effective mathematical modeling methods. The paper presents a consistent approach to the modeling of the distribution of illumination on a horizontal plane from the planar LED module, based on the Lambert type of radiation of a single point source. Simple mathematical expressions, programmed on a personal computer, are obtained. The example of a 25-LED floodlight has shown the ability of dynamic control the lighting characteristics of the module. Connecting patterns of separate LEDs or their groups allow to change the direction pattern of the lamp by the appropriate way of switching diodes with different aperture of radiation. The lighting power can be controlled within the linearity of the ampere-brightness characteristics by changing the current strength through the LED. The static selection of characteristics is controlled by the geometry of the location of discrete sources. The formation of uniform illumination of the plane is graphically illustrated. The electron-dynamic way of controlling the lighting parameters of the LED floodlight is confirmed by the inventor’s certificate.

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3D Printing & Pharmaceutical Manufacturing: Opportunities and Challenges

International Journal of Bioassays ◽

10.21746/ijbio.2016.01.006 ◽

2016 ◽

Vol 5 (01) ◽

pp. 4723 ◽

Cited By ~ 5

Author(s):

Bhusnure O. G.* ◽

Gholve V. S. ◽

Sugave B. K. ◽

Dongre R. C. ◽

Gore S. A. ◽

...

Keyword(s):

Drug Delivery ◽

Tissue Engineering ◽

3D Printing ◽

Computer Aided Design ◽

Patient Specific ◽

Computer Design ◽

3D Scaffolds ◽

Engineering Research ◽

Advantages And Disadvantages ◽

Computer Aided

Many researchers have attempted to use computer-aided design (C.A.D) and computer-aided manufacturing (CAM) to realize a scaffold that provides a three-dimensional (3D) environment for regeneration of tissues and organs. As a result, several 3D printing technologies, including stereolithography, deposition modeling, inkjet-based printing and selective laser sintering have been developed. Because these 3D printing technologies use computers for design and fabrication, and they can fabricate 3D scaffolds as designed; as a consequence, they can be standardized. Growth of target tissues and organs requires the presence of appropriate growth factors, so fabrication of 3Dscaffold systems that release these biomolecules has been explored. A drug delivery system (D.D.S) that administrates a pharmaceutical compound to achieve a therapeutic effect in cells, animals and humans is a key technology that delivers biomolecules without side effects caused by excessive doses. 3D printing technologies and D. D. Ss have been assembled successfully, so new possibilities for improved tissue regeneration have been suggested. If the interaction between cells and scaffold system with biomolecules can be understood and controlled, and if an optimal 3D tissue regenerating environment is realized, 3D printing technologies will become an important aspect of tissue engineering research in the near future. 3D Printing promises to produce complex biomedical devices according to computer design using patient-specific anatomical data. Since its initial use as pre-surgical visualization models and tooling molds, 3D Printing has slowly evolved to create one-of-a-kind devices, implants, scaffolds for tissue engineering, diagnostic platforms, and drug delivery systems. Fuelled by the recent explosion in public interest and access to affordable printers, there is renewed interest to combine stem cells with custom 3D scaffolds for personalized regenerative medicine. Before 3D Printing can be used routinely for the regeneration of complex tissues (e.g. bone, cartilage, muscles, vessels, nerves in the craniomaxillofacial complex), and complex organs with intricate 3D microarchitecture (e.g. liver, lymphoid organs), several technological limitations must be addressed. Until recently, tablet designs had been restricted to the relatively small number of shapes that are easily achievable using traditional manufacturing methods. As 3D printing capabilities develop further, safety and regulatory concerns are addressed and the cost of the technology falls, contract manufacturers and pharmaceutical companies that experiment with these 3D printing innovations are likely to gain a competitive edge. This review compose the basics, types & techniques used, advantages and disadvantages of 3D printing

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