Absence of an association between motor coordination and spatial orientation in lurcher mutant mice

1994 ◽  
Vol 24 (6) ◽  
pp. 497-501 ◽  
Author(s):  
Robert Lalonde ◽  
St�phane Thifault
Keyword(s):  
Spatial Orientation ◽  
Motor Coordination ◽  
Mutant Mice

Regional brain variations of cytochrome oxidase activity and motor coordination in Girk2Wv (Weaver) mutant mice

Neuroscience ◽  
2006 ◽  
Vol 142 (2) ◽  
pp. 437-449 ◽  
Author(s):  
C. Strazielle ◽  
V. Deiss ◽  
L. Naudon ◽  
R. Raisman-Vozari ◽  
R. Lalonde
Keyword(s):  
Cytochrome Oxidase ◽  
Oxidase Activity ◽  
Motor Coordination ◽  
Mutant Mice ◽  
Cytochrome Oxidase Activity ◽  
Regional Brain

Effects of midline and lateral cerebellar lesions on motor coordination and spatial orientation

1996 ◽  
Vol 739 (1-2) ◽  
pp. 1-11 ◽  
Author(s):  
C.C Joyal ◽  
C Meyer ◽  
G Jacquart ◽  
P Mahler ◽  
J Caston ◽  
...  
Keyword(s):  
Spatial Orientation ◽  
Motor Coordination ◽  
Cerebellar Lesions

scholarly journals Motor hypertonia and lack of locomotor coordination in mutant mice lacking DSCAM

2016 ◽  
Vol 115 (3) ◽  
pp. 1355-1371 ◽  
Author(s):  
Maxime Lemieux ◽  
Olivier D. Laflamme ◽  
Louise Thiry ◽  
Antoine Boulanger-Piette ◽  
Jérôme Frenette ◽  
...  
Keyword(s):  
Motor Coordination ◽  
Muscle Spindles ◽  
Mutant Mice ◽  
Electromyographic Activity ◽  
Wild Type ◽  
Neural Patterning ◽  
Step Cycle ◽  
Motor Circuits ◽  
Wide Range ◽  
Walking Speeds

Down syndrome cell adherence molecule (DSCAM) contributes to the normal establishment and maintenance of neural circuits. Whereas there is abundant literature regarding the role of DSCAM in the neural patterning of the mammalian retina, less is known about motor circuits. Recently, DSCAM mutation has been shown to impair bilateral motor coordination during respiration, thus causing death at birth. DSCAM mutants that survive through adulthood display a lack of locomotor endurance and coordination in the rotarod test, thus suggesting that the DSCAM mutation impairs motor control. We investigated the motor and locomotor functions of DSCAM2J mutant mice through a combination of anatomical, kinematic, force, and electromyographic recordings. With respect to wild-type mice, DSCAM2J mice displayed a longer swing phase with a limb hyperflexion at the expense of a shorter stance phase during locomotion. Furthermore, electromyographic activity in the flexor and extensor muscles was increased and coactivated over 20% of the step cycle over a wide range of walking speeds. In contrast to wild-type mice, which used lateral walk and trot at walking speed, DSCAM2J mice used preferentially less coordinated gaits, such as out-of-phase walk and pace. The neuromuscular junction and the contractile properties of muscles, as well as their muscle spindles, were normal, and no signs of motor rigidity or spasticity were observed during passive limb movements. Our study demonstrates that the DSCAM mutation induces dystonic hypertonia and a disruption of locomotor gaits.

scholarly journals Impaired motor coordination correlates with persistent multiple climbing fiber innervation in PKCγ mutant mice

Cell ◽  
1995 ◽  
Vol 83 (7) ◽  
pp. 1233-1242 ◽  
Author(s):  
Chong Chen ◽  
Masanobu Kano ◽  
Asa Abeliovich ◽  
Lu Chen ◽  
Shaowen Bao ◽  
...  
Keyword(s):  
Motor Coordination ◽  
Climbing Fiber ◽  
Mutant Mice

scholarly journals The Role of Ludotherapy in the Case of Children with Psychomotor Disorders

GYMNASIUM ◽  
2019 ◽  
Vol XIX (1 (Supplement)) ◽  
pp. 152
Author(s):  
Andreea-Gabriela Lazăr
Keyword(s):  
Physical Education ◽  
Spatial Orientation ◽  
Motor Coordination ◽  
Ocular Motor ◽  
School Year ◽  
Psychomotor Disorders ◽  
Segmental Coordination ◽  
Teaching Learning ◽  
Therapeutic Play

This research aimed to improve some components of psychomotor by using some therapeutic play activities in Physical Education and Sports lessons. The study was conducted at the „Stefan cel Mare” Gymnasium School in Putna, on five children aged between 7 and 10 years old. This experiment took place during a school year. The research is based on the premise that play (playful activities) conceived as therapy is part of the new trend of teaching-learning methods, which aim to transform the role of the teacher and to give new possibilities to the child with certain psychomotor disorders. The results have highlighted that the application of different ludo-therapy activities in physical education and sport lessons to children without mental deficiencies, but which have different psychomotor disorders, has led to the improvement of some components of psychomotor, namely static and dinamic balance, general coordination, segmental coordination, ocular - motor coordination and spatial orientation.

scholarly journals Impairment of motor coordination, Purkinje cell synapse formation, and cerebellar long-term depression in GluRδ2 mutant mice

Cell ◽  
1995 ◽  
Vol 81 (2) ◽  
pp. 245-252 ◽  
Author(s):  
Nobuko Kashiwabuchi ◽  
Kazutaka Ikeda ◽  
Kazuaki Araki ◽  
Tomoo Hirano ◽  
Katsuei Shibuki ◽  
...  
Keyword(s):  
Purkinje Cell ◽  
Motor Coordination ◽  
Synapse Formation ◽  
Mutant Mice ◽  
Long Term Depression ◽  
Cell Synapse

Effects of an ectodermal microceptor preparation on motor coordination in cerebellar mutant mice

1994 ◽  
Vol 49 (4) ◽  
pp. 777-779 ◽  
Author(s):  
Robert Lalonde ◽  
M.I. Botez ◽  
R. Bontemps ◽  
P. Loron
Keyword(s):  
Motor Coordination ◽  
Mutant Mice ◽  
Cerebellar Mutant

Exploration and motor coordination in dystonia musculorum mutant mice

1994 ◽  
Vol 56 (2) ◽  
pp. 277-280 ◽  
Author(s):  
Robert Lalonde ◽  
Christian C. Joyal ◽  
M.I. Botez
Keyword(s):  
Motor Coordination ◽  
Mutant Mice ◽  
Dystonia Musculorum
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