Genetic and environmental correlations between brain weight and maze learning in inbred strains of mice and their F1 hybrids

1976 ◽  
Vol 6 (1) ◽  
pp. 31-41 ◽  
Author(s):  
B. Padeh ◽  
M. Soller
1931 ◽  
Vol 14 (4) ◽  
pp. 421-443 ◽  
Author(s):  
Gregory Pincus

Young mice of a selected line of the dilute brown strain of mice exhibit over the range 15–25°C. (body temperature) a relation of frequency of breathing movements to temperature such that when fitted by the Arrhenius equation the data give a value for the constant µ of 24,000± calories or, less frequently, 28,000±. Young mice of an inbred albino strain show over the range 15–20°C. a value of µ = 34,000±, or, less frequently, 14,000±, with a critical temperature at about 20°C. and a value of µ = 14,000± above 20°C. The F1 hybrids of these two strains, and the backcross generations to either parent strain, exhibit only those four values of the temperature characteristic observed in the parent strains and none other. One may therefore speak of the inheritance of the value of the constant µ, but the inheritance shows in this instance no Mendelian behavior. Furthermore there appears to be inherited the occurrence (or absence) of a critical temperature at 20°C. These experiments indicate the "biological reality" of the temperature characteristics.


Genetics ◽  
1973 ◽  
Vol 75 (4) ◽  
pp. 663-670
Author(s):  
V G Dev ◽  
D A Miller ◽  
O J Miller

ABSTRACT The mitotic chromosomes of several inbred strains of mice and a series of F1 hybrids have been analyzed by quinacrine staining and further characterized by the centromeric heterochromatin banding (C-banding). Inbred strains had the same amount of C-banding material on homologous chromosomes but showed variation in the amount on different chromosomes. F1 hybrids showed characteristics of each parent and it appears that the amount of C-banding on each chromosome is a simple inherited polymorphism. In this study 12 different chromosomes could be distinguished by their C-banding, and these can be used as normal chromosome markers.


1964 ◽  
Vol 13 (1) ◽  
pp. 1-7
Author(s):  
Susumu MURAMATSU ◽  
Jun-ichiro HAYAKAWA ◽  
Junzo YAMADA ◽  
Takehiko TSUCHIYA

1998 ◽  
Vol 785 (2) ◽  
pp. 236-244 ◽  
Author(s):  
Lynn A Hyde ◽  
Blair J Hoplight ◽  
Victor H Denenberg

1965 ◽  
Vol 122 (4) ◽  
pp. 759-770 ◽  
Author(s):  
Richard W. Dutton

The early proliferative response previously demonstrated in rabbits has now been shown to follow the mixing of spleen cell suspensions from 2 inbred strains of mice or rats. The size of the response is comparable to that seen in cells from hyperimmune animals exposed to antigen in vitro. Autoradiographs of cells from stimulated cultures showed 1 to 4 per cent of the total population had incorporated thymidine. Modifications in the conditions necessary for the culture of mice and rat spleen cell suspensions and the measurement of thymidine incorporation are described. No responses were observed in isologous mixes. The responses obtained on mixing individual pairs of spleens from different strains showed relatively little variation. Responses were obtained in all of the 21 possible combinations between 7 inbred strains of mice. Responses were obtained when parental cells were mixed with their F1 hybrids. Analysis of these responses showed that, in every case, parental-F1 hybrid responses were less intense than those between the 2 parents. It was shown that there was no inherent defect in the ability of the hybrid cells to respond when mixed with an unrelated strain. The results suggested that the hybrid cells made no response to the parent cells although this was not conclusively established. This has been taken as circumstantial evidence that the response is immunological in nature. The significance of the vigor of the response and the large fraction of the immunologically competent cells that take part is discussed.


1982 ◽  
Vol 7 (2) ◽  
pp. 135-141 ◽  
Author(s):  
Rene Misslin ◽  
Eliane Kempf ◽  
Carmen Schleef ◽  
Serge Gobaille ◽  
Philippe Ropartz ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document