Unit responses of the reticular and ventral anterior thalamic nuclei of cats to orbitofrontal cortical stimulation

1975 ◽  
Vol 6 (5) ◽  
pp. 368-375
Author(s):  
M. Ya. Voloshin ◽  
V. F. Prokopenko
Keyword(s):  
Cortical Stimulation ◽  
Thalamic Nuclei ◽  
Anterior Thalamic Nuclei

scholarly journals Hippocampal–diencephalic–cingulate networks for memory and emotion: An anatomical guide

2017 ◽  
Vol 1 ◽  
pp. 239821281772344 ◽  
Author(s):  
Emma J. Bubb ◽  
Lisa Kinnavane ◽  
John P. Aggleton
Keyword(s):  
Prefrontal Cortex ◽  
Medial Temporal Lobe ◽  
Current Knowledge ◽  
Hippocampal Formation ◽  
Retrosplenial Cortex ◽  
Thalamic Nuclei ◽  
Mammillary Bodies ◽  
Individual Site ◽  
Multi Stage ◽  
Anterior Thalamic Nuclei

This review brings together current knowledge from tract tracing studies to update and reconsider those limbic connections initially highlighted by Papez for their presumed role in emotion. These connections link hippocampal and parahippocampal regions with the mammillary bodies, the anterior thalamic nuclei, and the cingulate gyrus, all structures now strongly implicated in memory functions. An additional goal of this review is to describe the routes taken by the various connections within this network. The original descriptions of these limbic connections saw their interconnecting pathways forming a serial circuit that began and finished in the hippocampal formation. It is now clear that with the exception of the mammillary bodies, these various sites are multiply interconnected with each other, including many reciprocal connections. In addition, these same connections are topographically organised, creating further subsystems. This complex pattern of connectivity helps explain the difficulty of interpreting the functional outcome of damage to any individual site within the network. For these same reasons, Papez’s initial concept of a loop beginning and ending in the hippocampal formation needs to be seen as a much more complex system of hippocampal–diencephalic–cingulate connections. The functions of these multiple interactions might be better viewed as principally providing efferent information from the posterior medial temporal lobe. Both a subcortical diencephalic route (via the fornix) and a cortical cingulate route (via retrosplenial cortex) can be distinguished. These routes provide indirect pathways for hippocampal interactions with prefrontal cortex, with the preponderance of both sets of connections arising from the more posterior hippocampal regions. These multi-stage connections complement the direct hippocampal projections to prefrontal cortex, which principally arise from the anterior hippocampus, thereby creating longitudinal functional differences along the anterior–posterior plane of the hippocampus.

Individual Subnuclei of the Rat Anterior Thalamic Nuclei Differently affect Spatial Memory and Passive Avoidance Tasks

Neuroscience ◽  
2020 ◽  
Vol 444 ◽  
pp. 19-32
Author(s):  
Vajihe Safari ◽  
Mohsen Nategh ◽  
Leila Dargahi ◽  
Mohammad Esmail Zibaii ◽  
Fariba Khodagholi ◽  
...  
Keyword(s):  
Spatial Memory ◽  
Passive Avoidance ◽  
Thalamic Nuclei ◽  
Anterior Thalamic Nuclei

Raising the profile of the anterior thalamus

1999 ◽  
Vol 22 (3) ◽  
pp. 447-448 ◽  
Author(s):  
John C. Dalrymple-Alford ◽  
Anna M. Gifkins ◽  
Michael A. Christie
Keyword(s):  
Perirhinal Cortex ◽  
Thalamic Nuclei ◽  
Anterior Thalamus ◽  
Target Article ◽  
Anterior Thalamic Nuclei

Three questions arising from Aggleton & Brown's target article are addressed. (1) Is there any benefit to considering the effects of partial lesions of the anterior thalamic nuclei (AT)? (2) Do the AT have a separate role in the proposed extended hippocampal system? (3) Should perirhinal cortex function be restricted to familiarity judgements?

scholarly journals Fos Imaging Reveals that Lesions of the Anterior Thalamic Nuclei Produce Widespread Limbic Hypoactivity in Rats

2002 ◽  
Vol 22 (12) ◽  
pp. 5230-5238 ◽  
Author(s):  
Trisha A. Jenkins ◽  
Rebecca Dias ◽  
Eman Amin ◽  
Malcolm W. Brown ◽  
John P. Aggleton
Keyword(s):  
Thalamic Nuclei ◽  
Anterior Thalamic Nuclei

scholarly journals Fornical and nonfornical projections from the rat hippocampal formation to the anterior thalamic nuclei

Hippocampus ◽  
2015 ◽  
Vol 25 (9) ◽  
pp. 977-992 ◽  
Author(s):  
Christopher M. Dillingham ◽  
Jonathan T. Erichsen ◽  
Shane M. O'Mara ◽  
John P. Aggleton ◽  
Seralynne D. Vann
Keyword(s):  
Hippocampal Formation ◽  
Thalamic Nuclei ◽  
Anterior Thalamic Nuclei

scholarly journals Organisation of cingulum bundle fibres connecting the anterior thalamic nuclei with the rodent anterior cingulate and retrosplenial cortices

2020 ◽  
Vol 4 ◽  
pp. 239821282095716
Author(s):  
Emma J. Bubb ◽  
Andrew J. D. Nelson ◽  
Thomas C. Cozens ◽  
John P. Aggleton
Keyword(s):  
Internal Capsule ◽  
Anterior Cingulate ◽  
Brain Atlas ◽  
Thalamic Nuclei ◽  
Major Pathway ◽  
Cingulum Bundle ◽  
Reciprocal Connections ◽  
Thalamic Projections ◽  
Anterior Thalamic Nuclei ◽  
Rats And Mice

Despite considerable interest in the properties of the cingulum bundle, descriptions of the composition of this major pathway in the rodent brain have not kept pace with advances in tract tracing. Using complementary approaches in rats and mice, this study examined the dense, reciprocal connections the anterior thalamic nuclei have with the cingulate and retrosplenial cortices, connections thought to be major contributors to the rodent cingulum bundle. The rat data came from a mixture of fluorescent and viral tracers, some injected directly into the bundle. The mouse data were collated from the Allen Mouse Brain Atlas. The projections from the three major anterior thalamic nuclei occupied much of the external medullary stratum of the cingulum bundle, where they were concentrated in its more medial portions. These anterior thalamic projections formed a rostral-reaching basket of efferents prior to joining the cingulum bundle, with anteromedial efferents taking the most rostral routes, often reaching the genu of the corpus callosum, while anterodorsal efferents took the least rostral route. In contrast, the return cortico-anterior thalamic projections frequently crossed directly through the bundle or briefly joined the internal stratum of the cingulum bundle, often entering the internal capsule before reaching the anterior thalamus. These analyses confirm that anterior thalamic connections comprise an important component of the rodent cingulum bundle, while also demonstrating the very different routes used by thalamo-cortical and cortico-thalamic projections. This information reveals how the composition of the cingulum bundle alters along its length.

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