Effects of oxytocin on ionic currents underlying rhythmic activity and contraction in uterine smooth muscle

1976 ◽  
Vol 363 (2) ◽  
pp. 113-118 ◽  
Author(s):  
Jean Mironneau
PLoS ONE ◽  
2011 ◽  
Vol 6 (4) ◽  
pp. e18685 ◽  
Author(s):  
Wing-Chiu Tong ◽  
Cecilia Y. Choi ◽  
Sanjay Karche ◽  
Arun V. Holden ◽  
Henggui Zhang ◽  
...  

1975 ◽  
Vol 246 (1) ◽  
pp. 1-36 ◽  
Author(s):  
C Y Kao ◽  
J R McCullough

1969 ◽  
Vol 54 (2) ◽  
pp. 145-165 ◽  
Author(s):  
Nels C. Anderson

These studies have developed and tested an experimental approach to the study of membrane ionic conductance mechanisms in strips of uterine smooth muscle. The experimental and theoretical basis for applying the double sucrose-gap technique is described along with the limitations of this system. Nonpropagating membrane action potentials were produced in response to depolarizing current pulses under current-clamp conditions. The stepwise change of membrane potential under voltage-clamp conditions resulted in a family of ionic currents with voltage- and time-dependent characteristics. In sodium-free solution the peak transient current decreased and its equilibrium potential shifted along the voltage axis toward a more negative internal potential. These studies indicate a sodium-dependent, regenerative excitation mechanism.


2021 ◽  
pp. 106689692199779
Author(s):  
Murat Celik

Leiomyoma is a benign mesenchymal tumor that develops from smooth muscle cells. It can present in various histological variants. Leiomyoma with bizarre nuclei is an infrequent variant of uterine smooth muscle neoplasm. It is characterized by focally or diffusely distributed bizarre cells on the background of a typical leiomyoma. These bizarre cells are large, multinucleated, or multilobulated and have an eosinophilic cytoplasm. Even though leiomyomas with bizarre nuclei display benign clinical behavior, their differential diagnosis from leiomyosarcoma can sometimes be difficult. Leiomyoma has been described most commonly in the uterus. There is no case of leiomyoma originating from paratubal cysts described in the literature. In this article, we present a rare case of leiomyoma with bizarre nuclei originating from a paratubal cyst.


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