Effects of cAMP on calcium currents in mollusk neurons differing in the sensitivity of their calcium conductance to serotonin action

1991 ◽  
Vol 22 (5) ◽  
pp. 441-447
Author(s):  
P. G. Kostyuk ◽  
E. A. Luk'yanets ◽  
P. A. Doroshenko
Keyword(s):  
Calcium Currents ◽  
Calcium Conductance ◽  
Mollusk Neurons

High Frequency–Induced Upregulation of Human Cardiac Calcium Currents

Circulation ◽  
1996 ◽  
Vol 93 (1) ◽  
pp. 120-128 ◽  
Author(s):  
Christophe Piot ◽  
Stéphanie Lemaire ◽  
Bernard Albat ◽  
Jacques Seguin ◽  
Joël Nargeot ◽  
...  
Keyword(s):  
High Frequency ◽  
Calcium Currents

scholarly journals Vitamin D3 analogs stimulate calcium currents in rat osteosarcoma cells.

1994 ◽  
Vol 269 (39) ◽  
pp. 23889-23893
Author(s):  
S. Yukihiro ◽  
G.H. Posner ◽  
S.E. Guggino
Keyword(s):  
Vitamin D3 ◽  
Calcium Currents ◽  
Osteosarcoma Cells

Enhancement of whole cell calcium currents following transient MCAO

2000 ◽  
Vol 884 (1-2) ◽  
pp. 129-138 ◽  
Author(s):  
Claus Bruehl ◽  
Tobias Neumann-Haefelin ◽  
O.W. Witte
Keyword(s):  
Calcium Currents ◽  
Whole Cell ◽  
Cell Calcium

Potassium and calcium currents activated by foetal calf serum in Balb-c 3T3 fibroblasts

1992 ◽  
Vol 1112 (2) ◽  
pp. 241-245 ◽  
Author(s):  
Davide Lovisolo ◽  
Luca Munaron ◽  
Francesco M. Baccino ◽  
Gabriella Bonelli
Keyword(s):  
Calf Serum ◽  
Calcium Currents ◽  
Foetal Calf Serum ◽  
3T3 Fibroblasts

Melatonin inhibits high voltage activated calcium currents in cultured rat dorsal root ganglion neurones

2001 ◽  
Vol 313 (1-2) ◽  
pp. 73-77 ◽  
Author(s):  
Ahmet Ayar ◽  
Duncan J. Martin ◽  
Mete Ozcan ◽  
Haluk Kelestimur
Keyword(s):  
Dorsal Root Ganglion ◽  
High Voltage ◽  
Dorsal Root ◽  
Calcium Currents

Calcium conductance of acetylcholine-induced endplate channels

Nature ◽  
1979 ◽  
Vol 279 (5714) ◽  
pp. 638-639 ◽  
Author(s):  
P. D. BREGESTOVSKI ◽  
R. MILEDI ◽  
I. PARKER
Keyword(s):  
Calcium Conductance

scholarly journals Sodium and calcium currents in dispersed mammalian septal neurons.

1991 ◽  
Vol 97 (2) ◽  
pp. 303-320 ◽  
Author(s):  
A Castellano ◽  
J López-Barneo
Keyword(s):  
Time Constant ◽  
Time Course ◽  
Calcium Currents ◽  
Closing Time ◽  
Patch Clamp Technique ◽  
Average Value ◽  
Time To Peak ◽  
Time Courses ◽  
Fast Activation ◽  
Septal Neurons

Voltage-gated Na+ and Ca2+ conductances of freshly dissociated septal neurons were studied in the whole-cell configuration of the patch-clamp technique. All cells exhibited a large Na+ current with characteristic fast activation and inactivation time courses. Half-time to peak current at -20 mV was 0.44 +/- 0.18 ms and maximal activation of Na+ conductance occurred at 0 mV or more positive membrane potentials. The average value was 91 +/- 32 nS (approximately 11 mS cm-2). At all membrane voltages inactivation was well fitted by a single exponential that had a time constant of 0.44 +/- 0.09 ms at 0 mV. Recovery from inactivation was complete in approximately 900 ms at -80 mV but in only 50 ms at -120 mV. The decay of Na+ tail currents had a single time constant that at -80 mV was faster than 100 microseconds. Depolarization of septal neurons also elicited a Ca2+ current that peaked in approximately 6-8 ms. Maximal peak Ca2+ current was obtained at 20 mV, and with 10 mM external Ca2+ the amplitude was 0.35 +/- 0.22 nA. During a maintained depolarization this current partially inactivated in the course of 200-300 ms. The Ca2+ current was due to the activity of two types of conductances with different deactivation kinetics. At -80 mV the closing time constants of slow (SD) and fast (FD) deactivating channels were, respectively, 1.99 +/- 0.2 and 0.11 +/- 0.03 ms (25 degrees C). The two kinds of channels also differed in their activation voltage, inactivation time course, slope of the conductance-voltage curve, and resistance to intracellular dialysis. The proportion of SD and FD channels varied from cell to cell, which may explain the differential electrophysiological responses of intracellularly recorded septal neurons.

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