Molecular changes during the activation of coagulation factor V by snake venom proteases

1983 ◽  
Vol 2 (3) ◽  
pp. 171-185
Author(s):  
Razia Rawala ◽  
Stefan Niewiarowski ◽  
Robert W. Colman
Keyword(s):  
Snake Venom ◽  
Coagulation Factor ◽  
Factor V ◽  
Molecular Changes ◽  
Coagulation Factor V

Coagulation Factor V Leiden Mutation Was Detected in the Patients with Activated Protein C Resistance in Thailand

1998 ◽  
Vol 80 (08) ◽  
pp. 344-345 ◽  
Author(s):  
Pasra Arnutti ◽  
Motofumi Hiyoshi ◽  
Wichai Prayoonwiwat ◽  
Oytip Nathalang ◽  
Chamaiporn Suwanasophon ◽  
...  
Keyword(s):  
Protein C ◽  
Activated Protein C ◽  
Factor V Leiden ◽  
Coagulation Factor ◽  
Factor V ◽  
Activated Protein C Resistance ◽  
Factor V Leiden Mutation ◽  
Coagulation Factor V

Phenotyping and Genotyping of Coagulation Factor V Leiden

1996 ◽  
Vol 75 (02) ◽  
pp. 267-269 ◽  
Author(s):  
H Engel ◽  
L Zwang ◽  
H H D M van Vliet ◽  
J J Michiles ◽  
J Stibbe ◽  
...  
Keyword(s):  
Factor V Leiden ◽  
Coagulation Factor ◽  
Diagnostic Value ◽  
Resistance Test ◽  
Amplification Refractory Mutation System ◽  
Factor V ◽  
Chain Reactions ◽  
Apc Resistance ◽  
Specificity And Sensitivity ◽  
Coagulation Factor V

SummaryThe currently used activated Protein C resistance test demonstrated to be of limited diagnostic value for the detection of the mutant Factor V Leiden. Moreover, this assay is not useful for patients under anticoagulant therapy. A modification of the APC resistance test, applying Factor V deficient plasma is described which demonstrates a specificity and sensitivity of 1.0. The superiority of the modified APC resistance test over the existing APC resistance test was verified by genotyping.For that purpose, the Amplification Refractory Mutation System (ARMS) was applied to the detection of the G to A mutation at position 1691 in the gene encoding coagulation Factor V. The mutation at that position could be easily detected by using each of two allele-specific oligonucleotide primers concomitantly with one common primer in two separate polymerase chain reactions, thereby amplifying a fragment of 186 base-pairs of the Factor V gene.

Coagulation Factor V: An Old Star Shines Again

1997 ◽  
Vol 78 (01) ◽  
pp. 427-433 ◽  
Author(s):  
Jan Rosing ◽  
Guido Tans
Keyword(s):  
Coagulation Factor ◽  
Factor V ◽  
Coagulation Factor V

scholarly journals Association of coagulation factor V with the platelet cytoskeleton.

1982 ◽  
Vol 257 (8) ◽  
pp. 4557-4563
Author(s):  
G P Tuszynski ◽  
P N Walsh ◽  
J R Piperno ◽  
A Koshy
Keyword(s):  
Coagulation Factor ◽  
Factor V ◽  
Coagulation Factor V

scholarly journals Thrombin-catalyzed activation of human coagulation factor V.

1982 ◽  
Vol 257 (11) ◽  
pp. 6556-6564 ◽  
Author(s):  
K Suzuki ◽  
B Dahlbäck ◽  
J Stenflo
Keyword(s):  
Coagulation Factor ◽  
Factor V ◽  
Coagulation Factor V

scholarly journals Factor V Kuwait: A Novel Mutation in the Coagulation Factor V Gene Discovered in Kuwait

2006 ◽  
Vol 15 (2) ◽  
pp. 102-105
Author(s):  
Mehrez M. Jadaon ◽  
Ali A. Dashti ◽  
Hend L. Lewis
Keyword(s):  
Novel Mutation ◽  
Coagulation Factor ◽  
Factor V ◽  
Coagulation Factor V ◽  
Factor V Gene ◽  
V Gene

Mutation in the Gene Coding for Coagulation Factor V and the Risk of Myocardial Infarction, Stroke, and Venous Thrombosis in Apparently Healthy Men

1995 ◽  
Vol 332 (14) ◽  
pp. 912-917 ◽  
Author(s):  
Paul M. Ridker ◽  
Charles H. Hennekens ◽  
Klaus Lindpaintner ◽  
Meir J. Stampfer ◽  
Paul R. Eisenberg ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Venous Thrombosis ◽  
Coagulation Factor ◽  
Factor V ◽  
Healthy Men ◽  
Gene Coding ◽  
Coagulation Factor V ◽  
Apparently Healthy
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