Application of HELP in nonarteritic anterior ischemic optic neuropathy: A prospective, randomized, controlled study

1997 ◽  
Vol 235 (1) ◽  
pp. 14-19 ◽  
Author(s):  
Anton Haas ◽  
Manfred Walzl ◽  
Friedrich Jesenik ◽  
Berengaria Walzl ◽  
Andrea Berghold ◽  
...  
Keyword(s):  
Optic Neuropathy ◽  
Anterior Ischemic Optic Neuropathy ◽  
Randomized Controlled Study ◽  
Controlled Study ◽  
Ischemic Optic Neuropathy ◽  
Randomized Controlled

scholarly journals Evaluation of enhanced external counterpulsation therapy for nonarteritic anterior ischemic optic neuropathy

2020 ◽  
Author(s):  
Lixia Lin ◽  
Wenhui Zhu ◽  
Nan Ma ◽  
Xiaofeng Lin ◽  
Hui Yang
Keyword(s):  
Optic Neuropathy ◽  
Visual Function ◽  
Anterior Ischemic Optic Neuropathy ◽  
Controlled Study ◽  
Control Group ◽  
Ischemic Optic Neuropathy ◽  
External Counterpulsation ◽  
Significant Difference ◽  
And Control ◽  
Enhanced External Counterpulsation

Abstract Background To explore the effects of enhanced external counterpulsation (EECP) and its underlying influencing factors in nonarteritic anterior ischemic optic neuropathy (NAION) patients. Methods Patients at Zhongshan Ophthalmic Center with recent-onset (<8 weeks) NAION were retrospectively recruited. The patients had decided whether or not they would undergo EECP treatment, and the patients who declined were included in the control group. The effectiveness of EECP was evaluated by comparing the visual function and fellow eye involvement in patients with and without EECP treatment. Results In total, 61 patients (76 eyes) were included. Twenty-nine patients (37 eyes) underwent EECP treatment, while 32 patients (39 eyes) were included in the control group. Mean time from NAION onset to EECP initiation was 27.59±16.70 days. In the EECP group, the mean EECP duration was 31.57±18.45 days. EECP was well tolerated by all patients. However, there was no significant difference in visual function between the EECP and control groups, regardless of time to treatment initiation. Furthermore, there was no evidence of the effectiveness of EECP in the subgroup analysis of patients with different systemic health conditions. Among the 42 patients with monocular NAION, the sequential attack rate was comparable between the EECP (27.78%) and control (25.00%) groups. Conclusion This study is the first nonrandomized controlled study to evaluate the effectiveness of EECP in NAION patients. Unfortunately, we failed to demonstrate the effectiveness of EECP in NAION at the 6-month follow-up. Any further application of EECP in NAION patients should be cautious.

scholarly journals Evaluation of enhanced external counterpulsation therapy for nonarteritic anterior ischemic optic neuropathy

2020 ◽  
Author(s):  
Lixia Lin ◽  
Wenhui Zhu ◽  
Nan Ma ◽  
Xiaofeng Lin ◽  
Hui Yang
Keyword(s):  
Optic Neuropathy ◽  
Visual Function ◽  
Anterior Ischemic Optic Neuropathy ◽  
Controlled Study ◽  
Control Group ◽  
Ischemic Optic Neuropathy ◽  
External Counterpulsation ◽  
Significant Difference ◽  
And Control ◽  
Enhanced External Counterpulsation

Abstract Background To explore the effects of enhanced external counterpulsation (EECP) and its underlying influencing factors in nonarteritic anterior ischemic optic neuropathy (NAION) patients. Methods Patients at Zhongshan Ophthalmic Center with recent-onset (<8 weeks) NAION were retrospectively recruited. The patients had decided whether or not they would undergo EECP treatment, and the patients who declined were included in the control group. The effectiveness of EECP was evaluated by comparing the visual function and fellow eye involvement in patients with and without EECP treatment. Results In total, 61 patients (76 eyes) were included. Twenty-nine patients (37 eyes) underwent EECP treatment, while 32 patients (39 eyes) were included in the control group. Mean time from NAION onset to EECP initiation was 27.59±16.70 days. In the EECP group, the mean EECP duration was 31.57±18.45 days. EECP was well tolerated by all patients. However, there was no significant difference in visual function between the EECP and control groups, regardless of time to treatment initiation. Furthermore, there was no evidence of the effectiveness of EECP in the subgroup analysis of patients with different systemic health conditions. Among the 42 patients with monocular NAION, the sequential attack rate was comparable between the EECP (27.78%) and control (25.00%) groups. Conclusion This study is the first nonrandomized controlled study to evaluate the effectiveness of EECP in NAION patients. Unfortunately, we failed to demonstrate the effectiveness of EECP in NAION at the 6-month follow-up. Any further application of EECP in NAION patients should be cautious.

scholarly journals Central Corneal Thickness Measurements in Nonarteritic Anterior Ischemic Optic Neuropathy Patients: A Controlled Study

2014 ◽  
Vol 2014 ◽  
pp. 1-3 ◽  
Author(s):  
Haneen Jabaly-Habib ◽  
Modi Naftali ◽  
George Habib
Keyword(s):  
Optic Neuropathy ◽  
Central Corneal Thickness ◽  
Corneal Thickness ◽  
Anterior Ischemic Optic Neuropathy ◽  
Controlled Study ◽  
Control Group ◽  
Ischemic Optic Neuropathy ◽  
History Of ◽  
Group 2 ◽  
Group 1

Purpose. To measure central corneal thickness (CCT) in patients with history of nonarteritic anterior ischemic optic neuropathy (NAION).Patients and Methods. Patients older than 40 years with a history of NAION (group 1) were prospectively evaluated including full eye examination and central corneal thickness (CCT) pachymetry. Patients with a history of intraocular surgery, corneal disease, glaucoma, and contact lens wear were excluded. Measurements were also performed in a gender and age matched control group (group 2).Results. Thirty-one eyes of 31 NAION patients in group 1 were included and 30 eyes of 30 participants in group 2. There were 15 men in group 1 and 9 in group 2P=0.141, and mean age of the patients was59±10years in group 1 versus61±11years in group 2P=0.708. Mean CCT was539±30microns in group 1 and550±33microns in group 2P=0.155.Conclusion. Patients with NAION have no special characteristic of CCT in contrast to the crowded optic disc known to be a significant anatomic risk factor for NAION. More studies should be carried out to investigate CCT and other structure related elements in NAION patients.

scholarly journals Randomized Controlled Phase 2a Study of RPh201 in Previous Nonarteritic Anterior Ischemic Optic Neuropathy

2019 ◽  
Vol 39 (3) ◽  
pp. 291-298 ◽  
Author(s):  
Eitan Z. Rath ◽  
Zadik Hazan ◽  
Konstantin Adamsky ◽  
Arieh Solomon ◽  
Zvi I. Segal ◽  
...  
Keyword(s):  
Optic Neuropathy ◽  
Anterior Ischemic Optic Neuropathy ◽  
Ischemic Optic Neuropathy ◽  
Randomized Controlled

Foreign language learning in older age does not improve memory or intelligence: Evidence from a randomized controlled study.

2020 ◽  
Vol 35 (2) ◽  
pp. 212-219
Author(s):  
Rasmus Berggren ◽  
Jonna Nilsson ◽  
Yvonne Brehmer ◽  
Florian Schmiedek ◽  
Martin Lövdén
Keyword(s):  
Foreign Language ◽  
Language Learning ◽  
Foreign Language Learning ◽  
Older Age ◽  
Randomized Controlled Study ◽  
Controlled Study ◽  
Randomized Controlled
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