Nucleotide sequence ofbup, an upstream gene in thebmi-1 proviral insertion locus

1993 ◽  
Vol 17 (1) ◽  
pp. 17-20 ◽  
Author(s):  
Y. Haupt ◽  
G. Barri ◽  
J. M. Adams
Keyword(s):  
Nucleotide Sequence ◽  
Upstream Gene ◽  
Insertion Locus

Structure and evolution of the Adh genes of Drosophila mojavensis.

Genetics ◽  
1988 ◽  
Vol 120 (3) ◽  
pp. 713-723
Author(s):  
P W Atkinson ◽  
L E Mills ◽  
W T Starmer ◽  
D T Sullivan
Keyword(s):  
Nucleotide Sequence ◽  
Sequence Divergence ◽  
Proximal Promoter ◽  
Drosophila Mojavensis ◽  
Upstream Gene ◽  
Ancestral Gene ◽  
Drosophila Mulleri ◽  
Adh Genes ◽  
Adh Gene ◽  
Dual Promoters

Abstract The nucleotide sequence of the Adh region of Drosophila mojavensis has been completed and the region found to contain a pseudogene, Adh-2 and Adh-1 arranged in that order. Comparison of the sequence divergence of these genes to one another and to the Adh region of Drosophila mulleri and other species has allowed the development of a model for the evolution of the duplication of the Adh genes. There have been two major events. An initial duplication of an Adh gene whose dual promoter structure was similar to Drosophila melanogaster, resulted in a species with two Adh genes, one of which may have had only a proximal promoter. A second duplication of this gene generated an Adh region containing three genes. It is proposed that one of these is the ancestral gene having dual promoters, while the other two possess only proximal promoters. Subsequent events have resulted in both a change in the regulation of Adh-2 such that it is expressed as if it had a "distal" type promoter and the mutational inactivation of the most upstream gene resulting in the creation of a pseudogene. The sequence of the D. mojavensis Adh region has also revealed the presence of an element which is composed of juxtaposed inverted imperfectly repeated elements. There is a surprising and not fully explainable strong similarity of the nucleotide sequence of the 5' flanking region of the pseudogene in D. mojavensis and D. mulleri.

Human cytokine gene nucleotide sequence alignments, 1998

1998 ◽  
Vol 25 (2‐3) ◽  
pp. 83-265 ◽  
Author(s):  
J. L. Bidwell ◽  
N. A. P. Wood ◽  
H. R. Morse ◽  
O. O. Olomolaiye ◽  
G. J. Laundy
Keyword(s):  
Nucleotide Sequence ◽  
Cytokine Gene ◽  
Sequence Alignments ◽  
Gene Nucleotide Sequence ◽  
Human Cytokine

Genomic structure and nucleotide sequence of AML1-ETO fusion genes in children with acute myeloid leukemia

2004 ◽  
Vol 216 (03) ◽  
Author(s):  
C Gall ◽  
T Langer ◽  
M Metzler ◽  
S Viehmann ◽  
J Harbott ◽  
...  
Keyword(s):  
Acute Myeloid Leukemia ◽  
Nucleotide Sequence ◽  
Myeloid Leukemia ◽  
Genomic Structure ◽  
Fusion Genes ◽  
Acute Myeloid

Sequencing Analysis and Phylogenetic Tree of HPV Isolated from Breast Cancer Patients at Thi-Qar Province/Iraq

2020 ◽  
pp. 37-40
Keyword(s):  
Nucleotide Sequence ◽  
Phylogenetic Tree ◽  
Evolutionary Relationship ◽  
Nucleotide Sequencing ◽  
Sequencing Analysis ◽  
Breast Cancer Patients ◽  
The North ◽  
Formalin Fixed Paraffin ◽  
Formalin Fixed Paraffin Embedded ◽  
History Of

Genetic variety examination has demonstrated fundamental to the understanding of the epidemiological and developmental history of Papillomavirus (HPV), for the development of accurate diagnostic tests and for efficient vaccine design. The HPV nucleotide diversity has been investigated widely among high-risk HPV types. To make the nucleotide sequence of HPV and do the virus database in Thi-Qar province, and compare sequences of our isolates with previously described isolates from around the world and then draw its phylogenetic tree, this study done. A total of 6 breast formalin-fixed paraffin-embedded (FFPE) of the female patients were included in the study, divided as 4 FFPE malignant tumor and 2 FFPE of benign tumor. The PCR technique was implemented to detect the presence of HPV in breast tissue, and the real-time PCR used to determinant HPV genotypes, then determined a complete nucleotide sequence of HPV of L1 capsid gene, and draw its phylogenetic tree. The nucleotide sequencing finding detects a number of substitution mutation (SNPs) in (L1) gene, which have not been designated before, were identified once in this study population, and revealed that the HPV16 strains have the evolutionary relationship with the South African race, while, the HPV33 and HPV6 showing the evolutionary association with the North American and East Asian race, respectively.

Genetic Identification of Algas on The Basis of The Analysis of 18s rRNA and rbcl of Genes Nucleotide Sequence and Development of Technology of Aquaculture Cultivation

2014 ◽  
Vol 2 (42) ◽  
pp. 291-291
Author(s):  
Z.B. Tekebayeva ◽  
A.B. Shevtsov ◽  
X.K. Rakhymzhan ◽  
K.A. Aituganov ◽  
G.A. Babayeva ◽  
...  
Keyword(s):  
Nucleotide Sequence ◽  
18S Rrna ◽  
Genetic Identification

FOCAL EPILEPSY CASE WITH A VARIANT OF THE NUCLEOTIDE SEQUENCE IN CACNA1H GENE

2019 ◽  
Vol 98 (6) ◽  
pp. 255-259
Author(s):  
T.V. Kozhanova ◽  
◽  
S.S. Zhilina ◽  
T.I. Mescheryakova ◽  
E.S. Bolshakova ◽  
...  
Keyword(s):  
Nucleotide Sequence ◽  
Focal Epilepsy

Cancer of the vulva: genetic aspects of pathogenesis

GYNECOLOGY ◽  
2018 ◽  
Vol 20 (4) ◽  
pp. 9-11 ◽  
Author(s):  
V V Sobolev ◽  
Z A Nevozinskaya ◽  
A G Soboleva ◽  
I M Korsunskaya
Keyword(s):  
Squamous Cell Carcinoma ◽  
Nucleotide Sequence ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Somatic Mutations ◽  
Genetic Research ◽  
Tp53 Gene ◽  
Gene Activity ◽  
Genetic Changes ◽  
Methylation Of Dna

The review is devoted to genetic research in cancer of the vulva. In genetic changes, the mutation irreversibly changes the nucleotide sequence of DNA, or the number of copies of chromosomes changes per cell. In epigenetics, the nucleotide sequence remains unchanged, but gene activity is regulated by methylation of DNA or modification of histones. Most of the studies analyzed are devoted to the study of mutations in the TP53 gene. Many studies indicate that somatic mutations are more common in HPV-negative than in HPV-positive patients. Epigenetic studies in the main devoted to hypermethylation. The gene CDKN2A is most often studied in epigenetic terms. For most of the studied genes, hypermethylation occurs more often in squamous cell carcinoma of the vulva than in the precursors.

Influence of two kinds of SV40 poly (A) signals on upstream gene expression

2010 ◽  
Vol 30 (6) ◽  
pp. 630-633
Author(s):  
Bing HOU ◽  
Hua-jun JIN ◽  
Wen-chao LIU ◽  
Qi-jun QIAN ◽  
Sai-qun LU
Keyword(s):  
Gene Expression ◽  
Upstream Gene
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