Exercise gated planar myocardial perfusion imaging using technetium-99m sestamibi for the diagnosis of coronary artery disease: an alternative to exercise tomographic imaging

1995 ◽  
Vol 22 (1) ◽  
pp. 40-48 ◽  
Author(s):  
François Jamar ◽  
Rifat Topcuoglu ◽  
Francisca Cauwe ◽  
Patrick De Coster ◽  
Véronique Roelants ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Myocardial Perfusion Imaging ◽  
Myocardial Perfusion ◽  
Perfusion Imaging ◽  
Tomographic Imaging ◽  
Technetium 99M Sestamibi ◽  
Technetium 99M ◽  
Artery Disease

Myocardial perfusion imaging with technetium-99m sestamibi SPECT in the evaluation of coronary artery disease

1990 ◽  
Vol 66 (13) ◽  
pp. E55-E62 ◽  
Author(s):  
Jamshid Maddahi ◽  
Hosen Kiat ◽  
Kenneth F. Van Train ◽  
Florence Prigent ◽  
John Friedman ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Myocardial Perfusion Imaging ◽  
Myocardial Perfusion ◽  
Perfusion Imaging ◽  
Technetium 99M Sestamibi ◽  
Technetium 99M ◽  
Artery Disease

scholarly journals Comparison of99mTc-N-DBODC5 and99mTc-MIBI of Myocardial Perfusion Imaging for Diagnosis of Coronary Artery Disease

2013 ◽  
Vol 2013 ◽  
pp. 1-10 ◽  
Author(s):  
Haiyan Ma ◽  
Sijin Li ◽  
Zhifang Wu ◽  
Jianzhong Liu ◽  
Haiyan Liu ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Myocardial Perfusion Imaging ◽  
Myocardial Perfusion ◽  
Perfusion Imaging ◽  
Photon Emission ◽  
The United States ◽  
Emission Computed Tomography ◽  
Technetium 99M ◽  
Artery Disease

Despite recent advances in therapeutic and diagnostic approaches, coronary artery disease (CAD) and its related cardiac disorders represent the most common cause of death in the United States. Nuclear myocardial perfusion imaging (MPI) technologies play a pivotal role in the diagnosis and treatment design for CAD. Recently, in order to develop improved MPI agents for diagnosis of CAD,99mTc-[bis(dimethoxypropylphosphinoethyl)-ethoxyethyl-amine(PNP5)]-[bis(N-ethoxyethyl)dithiocarbamato(DBODC)]nitride(N-DBODC5)(99mTc-N-DBODC5) with a faster liver clearance than conventional single-photon emission computed tomography (SPECT) imaging agents (technetium 99m sestamibi (99mTc-MIBI) or technetium 99m tetrofosmin) has been introduced. In preclinical and phase I studies,99mTc-N-DBODC5 has shown characteristics of an essentially ideal MPI tracer. Importantly, however, there is no data to support the use of99mTc-N-DBODC5 to evaluate myocardial ischemia in patients with suspected CAD. The present study was designed to assess the clinical value of this agent; the findings of stress and rest MPI after the administration of this agent were compared to those of stress and rest99mTc-MIBI, as well as those of coronary angiography, with respect to the detection of CAD. Our findings indicated the usefulness of99mTc-N-DBODC5 as a promising MPI agent.

Sign in / Sign up

Export Citation Format

Share Document