Strain gauge plethysmography for blood flow measurements in the legs of children

1975 ◽  
Vol 3 (1) ◽  
pp. 29-33 ◽  
Author(s):  
Wigher Mortensson ◽  
Torgil Hallb��k ◽  
Nils-Rune Lundstr�m
1983 ◽  
Vol 22 (04) ◽  
pp. 204-209
Author(s):  
P. Gizdulich ◽  
M. Mlchelutti

Strain gauge venous occlusion plethysmography continues to be employed for peripheral muscular blood flow measurements, even though its reliability is dubious.We have already studied reproducibility for short-term (several minutes) and for long-term (one or two days) measurements. Our present aim is to analyze medium-term (several hours) reproducibility, keeping in mind the application of this technique in pharmacological experimentation.We used an analysis of variance with repeated measurements over 4 hours in 24 healthy subjects, considering the following variation factors: venous occlusion pressure (vop); muscular activity; the sampling interval. Two levels were assigned to each factor: 30 or 50 mmHg for the vop, yes or no for the muscular activity and 5 or 20 minutes for the sampling interval.We verified (p <.01) a mean decreasing trend. After an initial 15% increase, values decreased to 85% of the initial value. The trend appears to be modified only by vop. As for the mean value, independently from the trend, we verified that it is significantly (p < .05) modified by muscular activity—as expected—and by the sampling time interval. The statistical analysis excludes trend shape dependence on different metabolic requirements due to the duration of the experiment.


1990 ◽  
Vol 79 (1) ◽  
pp. 81-87 ◽  
Author(s):  
Lennart Jorfeldt ◽  
Hans Rutberg

1. In eight healthy volunteers we compared leg blood flow, as determined in a calf segment by strain-gauge plethysmography, with the flow measured by a constant-rate infusion of Indocyanine Green dye into the femoral artery. The representativeness of the calf segment was evaluated by complementary measurements with additional strain gauges attached around the proximal and distal crural and the distal thigh segments (n = 6). Furthermore, we investigated the influence of the catheterization procedure and a simulated vascular puncture, as well as repeated venous occlusions, on blood flow and on arterial and femoral venous substrate concentrations and blood gases (n = 8). 2. The leg blood flow measured by dye dilution was 0.31 ± 0.03 litre/min (mean ± sem). The blood flow in the calf segments was 14.8 ± 1.6 ml min−1 litre−1 and no difference between the legs was observed. Extended to the whole leg the plethysmographic blood flow was 0.17 ± 0.01 litre/min and thus lower (43 ± 7%, P < 0.001) than the flow determined by the indicator-dilution method. Blood flow in the legs was not influenced by catheterization or sham punctures of the vessels or by repeated venous occlusions. 3. The concentrations of glucose, lactate and glycerol, as well as blood gas variables, in arterial and femoral venous blood did not change during the study or decreased so slightly (pH and lactate) that the arteriovenous difference was not influenced. 4. We conclude that the blood flow of the total leg cannot be satisfactorily estimated from strain-gauge plethysmography of a single calf segment. Strain-gauge plethysmography can therefore not be recommended for quantitative studies of substrate turnover in the leg tissues applying the Fick principle. Catheterization of the femoral vessels, or manipulations close to them with a thin cannula or repeated venous occlusions, has no significant effect on leg blood flow and substrate exchange.


Neurosurgery ◽  
2002 ◽  
Vol 50 (5) ◽  
pp. 996-1005 ◽  
Author(s):  
Randolph S. Marshall ◽  
Ronald M. Lazar ◽  
William L. Young ◽  
Robert A. Solomon ◽  
Shailendra Joshi ◽  
...  

1975 ◽  
Vol 49 (3) ◽  
pp. 17P-17P
Author(s):  
Maurice R. Cross ◽  
Clive Weller ◽  
E. B. Raftery

Sign in / Sign up

Export Citation Format

Share Document