ACTH-induced inhibition of endogenous rat brain protein phosphorylation in vitro: Structure activity

1978 ◽  
Vol 3 (4) ◽  
pp. 455-463 ◽  
Author(s):  
Henk Zwiers ◽  
Victor Marius Wiegant ◽  
Peter Schotman ◽  
Willem Hendrik Gispen
Keyword(s):  
Protein Phosphorylation ◽  
Rat Brain ◽  
Brain Protein ◽  
Structure Activity

scholarly journals STUDIES ON A NEW METABOLITE AND ITS OXIDATION IN THE PRESENCE OF ASCORBIC ACID

1947 ◽  
Vol 31 (2) ◽  
pp. 195-201 ◽  
Author(s):  
Frederick Bernheim ◽  
Karl M. Wilbur ◽  
Dorothea B. Fitzgerald
Keyword(s):  
Ascorbic Acid ◽  
Acid Solution ◽  
Rat Brain ◽  
Aminobenzoic Acid ◽  
Brain Protein ◽  
Yellow Color ◽  
Liver And Kidney ◽  
Hydroxy Compounds

1. A number of tissues, in particular, brain, liver, and kidney, incubated aerobically in vitro as slices or ground suspensions produce a compound which combines with p-aminobenzoic acid in acid solution to form a yellow color. 2. A study of this reaction in rat brain has shown that this compound can be produced when washed boiled brain protein is incubated aerobically with ascorbic acid. The latter acts as a catalyst to break the linkage between the protein and the compound. Oxygen is taken up in the process. 3. A number of aromatic hydroxy compounds such as epinephrine and catechol inhibit the reaction. Cyanide has little or no effect. No reaction occurs anaerobically. 4. The occurrence of the reaction in some animals has been described.

scholarly journals ACTH, cyclic nucleotides, and brain protein phosphorylation in vitro

1976 ◽  
Vol 1 (6) ◽  
pp. 669-677 ◽  
Author(s):  
H. Zwiers ◽  
H. D. Veldhuis ◽  
P. Schotman ◽  
W. H. Gispen
Keyword(s):  
Protein Phosphorylation ◽  
Cyclic Nucleotides ◽  
Brain Protein

Human brain protein phosphorylation in vitro: Cyclic AMP stimulation of electrophoretically-separated substrates

1981 ◽  
Vol 222 (2) ◽  
pp. 323-333 ◽  
Author(s):  
Aryeh Routtenberg ◽  
David G. Morgan ◽  
Richard G. Conway ◽  
Michael J. Schmidt ◽  
Bernardino Ghetti
Keyword(s):  
Cyclic Amp ◽  
Human Brain ◽  
Protein Phosphorylation ◽  
Brain Protein ◽  
Stimulation Of

scholarly journals Pre-incubation of subcellular fractions from rat cerebral cortex inactivates protein phosphorylation

1981 ◽  
Vol 199 (1) ◽  
pp. 269-272 ◽  
Author(s):  
P R Dunkley ◽  
P J Robinson
Keyword(s):  
Cerebral Cortex ◽  
Cyclic Amp ◽  
Protein Phosphorylation ◽  
Rat Brain ◽  
Subcellular Fractions ◽  
Rat Cerebral Cortex ◽  
Substrate Availability ◽  
Physiological Relevance

Pre-incubation of various subcellular fractions from rat brain caused a significant decrease in the phosphorylation of individual polypeptides. The rate and extent of this loss of labelling was not uniform and polypeptides whose phosphorylation was independent of cyclic AMP were primarily affected, whereas substrate availability remained unaltered. It is recommended that pre-incubation effects must be carefully monitored if valid conclusions are to be made about the physiological relevance of changes in protein phosphorylation observed in vitro.

In vitro inhibition of rat brain protein kinase C by rhodamine 6G

1987 ◽  
Vol 36 (8) ◽  
pp. 1231-1235 ◽  
Author(s):  
Catherine A. O'Brian ◽  
I.Bernard Weinstein
Keyword(s):  
Protein Kinase C ◽  
Protein Kinase ◽  
Rat Brain ◽  
Rhodamine 6G ◽  
Brain Protein ◽  
Kinase C ◽  
In Vitro Inhibition

Changes in sensitivity of in vitro rat brain protein synthesis to the acute action of ethanol and isopropanol as a consequence of the long-term ingestion of isopropanol

1991 ◽  
Vol 65 (6) ◽  
pp. 500-504
Author(s):  
Raquel Muñoz ◽  
Rosario Iglesias ◽  
José Miguel Ferreras ◽  
Maria Angeles Rojo ◽  
Francisco Javier Arias ◽  
...  
Keyword(s):  
Protein Synthesis ◽  
Rat Brain ◽  
Brain Protein ◽  
Brain Protein Synthesis

Oral aluminum alters in vitro protein phosphorylation and kinase activities in rat brain

1990 ◽  
Vol 11 (3) ◽  
pp. 209-216 ◽  
Author(s):  
Gail V.W. Johnson ◽  
Keith W. Cogdill ◽  
Richard S. Jope
Keyword(s):  
Protein Phosphorylation ◽  
Rat Brain ◽  
Vitro Protein

Adaptation of in vitro rat brain protein synthesis to long-term ingestion of n-butanol

1990 ◽  
Vol 517 (1-2) ◽  
pp. 330-332 ◽  
Author(s):  
R. Mun˜oz ◽  
J.M. Ferreras ◽  
R. Iglesias ◽  
M.J. Merino ◽  
T. Girbés
Keyword(s):  
Protein Synthesis ◽  
Rat Brain ◽  
Brain Protein ◽  
Brain Protein Synthesis

In Vitro Activation of Rat Brain Protein Kinase C by Polyenoic Very-Long-Chain Fatty Acids

2008 ◽  
Vol 62 (4) ◽  
pp. 1546-1551 ◽  
Author(s):  
Stephen J. Hardy ◽  
Antonio Ferrante ◽  
Brenton S. Robinson ◽  
David W. Johnson ◽  
Alf Poulos ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Protein Kinase C ◽  
Protein Kinase ◽  
Rat Brain ◽  
Long Chain Fatty Acids ◽  
Brain Protein ◽  
Kinase C ◽  
In Vitro Activation ◽  
Long Chain
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