Conversion and binding of tetraiodothyronine in developing rat brain

1981 ◽  
Vol 6 (7) ◽  
pp. 743-753 ◽  
Author(s):  
T. Valcana
Keyword(s):  
Rat Brain ◽  
Developing Rat

Regulation of tubulin by triiodothyronine in hypothyroid rat brain

1985 ◽  
Vol 5 (8) ◽  
pp. 643-648 ◽  
Author(s):  
Anjana Mazumder ◽  
Kamal Das ◽  
Pranab K. Sarkar
Keyword(s):  
Protein Synthesis ◽  
Rat Brain ◽  
Brain Maturation ◽  
Normal Brain ◽  
Neonatal Brain ◽  
Organ Cultures ◽  
Postnatal Brain ◽  
Enhanced Sensitivity ◽  
Brain Exposure ◽  
Developing Rat

The effect of T3 (triiodothyronine) on the induction of tubulin in hypothyroid developing rat brain has been examined using organ cultures of brains from late fetal, neonatal and postnatalrats. The neonatal brain displayed maximum sensitivity to T3. Hypothyroidism resulted in a 26% decline in the level of tubulin in the neonatal brain as opposed to a 5–15% decline in the fetal or postnatal brain. Exposure of the hypothyroi d neonatal brain to T3 for 2 h in culture led to a 61% rise in the level of tubulin in contrast to a 41% increase seen in the case of normal brain. Total protein synthesis was not significantly affected. The preferential decline of tubulin in the neonatal hypothyroid brain, its enhanced sensitivity to T3 compared to normal brain, and the coincidence of the period of sensitivity to that of brain maturation indicate that the regulation of the level of tubulin by T3 in the developing brain is a natural ontogenic phenomenon.

scholarly journals Effect of Hypoxic-Ischemic Injury on Serine Palmitoyltransferase Activity in the Developing Rat Brain

Pathobiology ◽  
2008 ◽  
Vol 75 (6) ◽  
pp. 330-334 ◽  
Author(s):  
Masaki Daigo ◽  
Yasuhiro Arai ◽  
Kyoichi Oshida ◽  
Yohei Kitamura ◽  
Masaharu Hayashi ◽  
...  
Keyword(s):  
Rat Brain ◽  
Ischemic Injury ◽  
Serine Palmitoyltransferase ◽  
Developing Rat ◽  
Hypoxic Ischemic Injury

scholarly journals Differential patterns of semaphorin expression in the developing rat brain

1998 ◽  
Vol 10 (4) ◽  
pp. 1215-1229 ◽  
Author(s):  
Irini Skaliora ◽  
Wolf Singer ◽  
Heinrich Betz ◽  
Andreas W. Püschel
Keyword(s):  
Rat Brain ◽  
Developing Rat

The metabolism of d- and l-3-hydroxybutyrate in developing rat brain

1984 ◽  
Vol 31 (3) ◽  
pp. 332-346 ◽  
Author(s):  
Kenneth R. Swiatek ◽  
George J. Dombrowski ◽  
Kuen-Lan Chao
Keyword(s):  
Rat Brain ◽  
Developing Rat
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