Palladium-catalyzed cross-coupling of aryldiazonium salts with tetramethyltin in aqueous medium

1990 ◽  
Vol 39 (11) ◽  
pp. 2419-2419 ◽  
Author(s):  
N. A. Bumagin ◽  
L. I. Sukhomlinova ◽  
T. P. Tolstaya ◽  
A. N. Vanchikov ◽  
I. P. Beletskaya
Keyword(s):  
Aqueous Medium ◽  
Cross Coupling ◽  
Palladium Catalyzed

ChemInform Abstract: Palladium-Catalyzed Cross-Coupling of Aryldiazonium Salts with Tetramethyltin in an Aqueous Medium.

ChemInform ◽  
2010 ◽  
Vol 23 (28) ◽  
pp. no-no
Author(s):  
N. A. BUMAGIN ◽  
L. I. SUKHOMLINOVA ◽  
T. P. TOLSTAYA ◽  
A. N. VANCHIKOV ◽  
I. P. BELETSKAYA
Keyword(s):  
Aqueous Medium ◽  
Cross Coupling ◽  
Palladium Catalyzed

Palladium-Catalyzed Cross-Coupling Reactions in a Homogeneous Aqueous Medium

Synlett ◽  
1992 ◽  
Vol 1992 (09) ◽  
pp. 715-717 ◽  
Author(s):  
Jean Pierre Genet ◽  
Errol Blart ◽  
Monique Savignac
Keyword(s):  
Aqueous Medium ◽  
Cross Coupling ◽  
Coupling Reactions ◽  
Cross Coupling Reactions ◽  
Palladium Catalyzed

Functionalization of sulfophthalocyanines in aqueous medium by palladium-catalyzed cross-coupling reactions

2006 ◽  
Vol 47 (47) ◽  
pp. 8275-8278 ◽  
Author(s):  
Hasrat Ali ◽  
Olivier St-Jean ◽  
Jean-Philip Tremblay-Morin ◽  
Johan E. van Lier
Keyword(s):  
Aqueous Medium ◽  
Cross Coupling ◽  
Coupling Reactions ◽  
Cross Coupling Reactions ◽  
Palladium Catalyzed

Suzuki–Miyaura cross-coupling for chemoproteomic applications

2020 ◽  
Author(s):  
Jian Cao ◽  
Ernest Armenta ◽  
Lisa Boatner ◽  
Heta Desai ◽  
Neil Chan ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Cross Coupling ◽  
Protein Profiling ◽  
Protein Labeling ◽  
Caspase 8 ◽  
Complex Cell ◽  
Bioorthogonal Chemistry ◽  
Reaction Conditions ◽  
Target Deconvolution ◽  
Palladium Catalyzed

Bioorthogonal chemistry is a mainstay of chemoproteomic sample preparation workflows. While numerous transformations are now available, chemoproteomic studies still rely overwhelmingly on copper-catalyzed azide –alkyne cycloaddition (CuAAC) or 'click' chemistry. Here we demonstrate that gel-based activity-based protein profiling (ABPP) and mass-spectrometry-based chemoproteomic profiling can be conducted using Suzuki–Miyaura cross-coupling. We identify reaction conditions that proceed in complex cell lysates and find that Suzuki –Miyaura cross-coupling and CuAAC yield comparable chemoproteomic coverage. Importantly, Suzuki–Miyaura is also compatible with chemoproteomic target deconvolution, as demonstrated using structurally matched probes tailored to react with the cysteine protease caspase-8. Uniquely enabled by the observed orthogonality of palladium-catalyzed cross-coupling and CuAAC, we combine both reactions to achieve dual protein labeling.

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